ID A0A2K6QRN2_RHIRO Unreviewed; 430 AA.
AC A0A2K6QRN2;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=Tektin {ECO:0000256|RuleBase:RU367040};
GN Name=TEKT2 {ECO:0000313|Ensembl:ENSRROP00000031431.1};
OS Rhinopithecus roxellana (Golden snub-nosed monkey) (Pygathrix roxellana).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Colobinae; Rhinopithecus.
OX NCBI_TaxID=61622 {ECO:0000313|Ensembl:ENSRROP00000031431.1, ECO:0000313|Proteomes:UP000233200};
RN [1] {ECO:0000313|Ensembl:ENSRROP00000031431.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- FUNCTION: Microtubule inner protein (MIP) part of the dynein-decorated
CC doublet microtubules (DMTs) in cilia and flagellar axoneme. Forms
CC filamentous polymers in the walls of ciliary and flagellar
CC microtubules. Required for normal sperm mobility.
CC {ECO:0000256|RuleBase:RU367040}.
CC -!- SUBCELLULAR LOCATION: Cell projection, cilium, flagellum
CC {ECO:0000256|RuleBase:RU367040}. Cytoplasm, cytoskeleton, cilium
CC axoneme {ECO:0000256|ARBA:ARBA00004430}. Cytoplasm, cytoskeleton,
CC microtubule organizing center {ECO:0000256|ARBA:ARBA00004267}.
CC -!- SIMILARITY: Belongs to the tektin family.
CC {ECO:0000256|ARBA:ARBA00007209, ECO:0000256|RuleBase:RU367040}.
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DR RefSeq; XP_010358715.1; XM_010360413.1.
DR RefSeq; XP_010358717.1; XM_010360415.1.
DR AlphaFoldDB; A0A2K6QRN2; -.
DR STRING; 61622.ENSRROP00000031431; -.
DR Ensembl; ENSRROT00000055846.1; ENSRROP00000031431.1; ENSRROG00000039414.1.
DR GeneID; 104660149; -.
DR KEGG; rro:104660149; -.
DR CTD; 27285; -.
DR GeneTree; ENSGT00950000182894; -.
DR OMA; FDHRGKM; -.
DR OrthoDB; 3788977at2759; -.
DR Proteomes; UP000233200; Unplaced.
DR GO; GO:0005879; C:axonemal microtubule; IEA:Ensembl.
DR GO; GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
DR GO; GO:0031514; C:motile cilium; IEA:UniProtKB-SubCell.
DR GO; GO:0030317; P:flagellated sperm motility; IEA:UniProtKB-UniRule.
DR GO; GO:0036159; P:inner dynein arm assembly; IEA:Ensembl.
DR InterPro; IPR048256; Tektin-like.
DR InterPro; IPR000435; Tektins.
DR PANTHER; PTHR19960; TEKTIN; 1.
DR PANTHER; PTHR19960:SF7; TEKTIN-2; 1.
DR Pfam; PF03148; Tektin; 1.
DR PRINTS; PR00511; TEKTIN.
PE 3: Inferred from homology;
KW Cell projection {ECO:0000256|RuleBase:RU367040};
KW Cilium {ECO:0000256|ARBA:ARBA00023069, ECO:0000256|RuleBase:RU367040};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Flagellum {ECO:0000256|RuleBase:RU367040};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Reference proteome {ECO:0000313|Proteomes:UP000233200}.
FT COILED 134..161
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 276..310
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 342..376
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 430 AA; 49690 MW; 28E63773782A8521 CRC64;
MATLSVKPSQ RFQLPDWHTN SYLLSTNAQL QRDASHQIRQ EARVLRNETN NQTIWDEHDN
RTRLVERIDT VNRWKEMLDK CLTDLDAEID ALTQMKDSAE QNLQAKNLPL DVAIECLTLR
ESRRDIDVVK DPVEDELHKE VEVIEATKKA LQQKVSQAFE QLCLLQEVRQ QLNSDHRGKM
ETLEIDRGCL SLNLRSPNIS LKVDPTRVPD GSTTLQQWDD FSQFNKDRGE AEMKAATELR
EAIALTIAET NNELEAQRVA TEFAFRKRLR EMEKVYSELK WQEKNTLEEI AELQEDIRHL
EEDLRTKFLS LKLSHTRLDA RTYRPNVELC RDQAQYGLTD EVHQLEATIA ALKQKLAQAQ
DALDALYKHL ARLQADIACK ANSMLLDTKC MDTRRKLTVP AEKFVPEVDT FTRTTDSTLS
PLKSCHLELA
//
