ID A0A2K6QUC1_RHIRO Unreviewed; 3196 AA.
AC A0A2K6QUC1;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Dachsous cadherin-related 1 {ECO:0000313|Ensembl:ENSRROP00000032365.1};
GN Name=DCHS1 {ECO:0000313|Ensembl:ENSRROP00000032365.1};
OS Rhinopithecus roxellana (Golden snub-nosed monkey) (Pygathrix roxellana).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Colobinae; Rhinopithecus.
OX NCBI_TaxID=61622 {ECO:0000313|Ensembl:ENSRROP00000032365.1, ECO:0000313|Proteomes:UP000233200};
RN [1] {ECO:0000313|Ensembl:ENSRROP00000032365.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR Ensembl; ENSRROT00000056793.1; ENSRROP00000032365.1; ENSRROG00000039837.1.
DR GeneTree; ENSGT00940000161822; -.
DR Proteomes; UP000233200; Unplaced.
DR GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR GO; GO:0005509; F:calcium ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0007156; P:homophilic cell adhesion via plasma membrane adhesion molecules; IEA:InterPro.
DR CDD; cd11304; Cadherin_repeat; 26.
DR Gene3D; 2.60.40.60; Cadherins; 26.
DR InterPro; IPR002126; Cadherin-like_dom.
DR InterPro; IPR015919; Cadherin-like_sf.
DR InterPro; IPR020894; Cadherin_CS.
DR PANTHER; PTHR24028; CADHERIN-87A; 1.
DR PANTHER; PTHR24028:SF310; STARRY NIGHT; 1.
DR Pfam; PF00028; Cadherin; 22.
DR PRINTS; PR00205; CADHERIN.
DR SMART; SM00112; CA; 26.
DR SUPFAM; SSF49313; Cadherin-like; 26.
DR PROSITE; PS00232; CADHERIN_1; 10.
DR PROSITE; PS50268; CADHERIN_2; 26.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837, ECO:0000256|PROSITE-
KW ProRule:PRU00043}; Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000233200};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..39
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 40..3196
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014364208"
FT TRANSMEM 2833..2859
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 40..140
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 141..252
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 253..359
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 371..469
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 479..575
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 576..682
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 683..787
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 788..891
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 892..997
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 998..1108
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 1103..1163
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 1232..1335
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 1336..1445
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 1445..1548
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 1549..1650
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 1651..1754
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 1755..1859
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 1882..1967
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 1968..2069
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 2070..2175
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 2175..2274
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 2275..2380
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 2381..2500
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 2501..2604
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 2605..2711
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 2712..2831
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT REGION 2866..2938
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2959..2985
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3131..3196
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3137..3160
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 3196 AA; 335492 MW; 9834A3572DB6C8E9 CRC64;
MQKEPGIVPS CPGRKSPRPR HLLPLLLLLL GAGVPGAWAQ AGSLDLQIDE EQPAGTLIGD
ISAGLPAGTA APLMYFISAQ EGSGVGTDLA IDEHSGVVRT ARVLDREQRD RYRFTAVTPD
GATVEVTVRV ADINDHAPAF PQARAALQVP EHTAFGTCYP LEPARDADAG HLGTQGYALS
GDGAGETFRL ETRPGPDGAP VPELVVTGEL DRENRSHYML QLEAYDGGSP PRRAQTLLDV
TLLDINDHAP AFNQSRYHAV VSESLAPGSP VLQVFASDAD AGANGAVTYE INRRQSEGDG
PFSIDAHTGL LQLERPLDFE QRRVHELVVQ ARDGGAHPEL GSAFVTVHVR DANDNQPSMT
VIFLSADGSP QVSEAAPPGQ LVARISVSDP DDGDFAHVNV SLEGGEGHFA LSTQDSVIYL
VCVARRLDRE ERDAYNLRVT ATDSGSPPLR AEAAFVLHVT DVNDNAPAFD HQFYQPEPLP
EVALPGSFVV RVTARDPDQG TNGQVTYSLA PGAHTHWFSI DPTSGIITTA ASLDYELEPQ
PQLTVVATDG GLPPLASSAT VNVALQDVND NEPQFQRTFY NASLPEGTQP GTCFLQVTAT
DADSGLFGLL SYSLGAGLGS FGSPPFRIDA HSGDVCTTRT LDRDQGPSSF DFTVTAVDGG
GLKSMVYVKV FLSDENDNPP QFYPREYAAS ISAQSPPGTA VLRVRAHDPD QGSHGRLTYH
ILAGNSPPLF ALDEQSGLLT VAWPLARRAN SVVQLEIGAQ DGGGLQTEPS ARVNISIVPG
TPTPPIFEQL QYVFSVPEDV APGTSVGIVQ AHNPPGRLAP VTLSLSGGDP RGLFSLDVIS
GLLQTLRPLD RELLGPVLEL EVRAGSGVPP AFAVARVRVL LDDVNDNSPA FPAPEDTVLL
PPNTAPGTPI YTLRALDPDS GVNSRVTFTL LAGGGGAFTV DPTTGHVRLM RPLGPSGGPA
HELELEARDG GSPPRTSHFR LRVVVQDVGT RGLAPQFDSP TYRVDLPSGT TPGTQVLQVQ
AQAPDGGPVT YHLAAEGASS PFGLEPQSGW LWVRAALDRE AQELYILKVM AVSGSKAELG
QQTGTATVRV SILNQNEHSP RLSEDPTFLA VAENQPPGTS VGRVFATDRD SGPNGRLTYS
LQQLSEDSKA FRIHPQTGTL VTTLQARDPD EGENGTILYT LTGMGVERRE LVGDVAPASW
ESLGSSSSKV LPSARLAEPP PDLAELDPAA PVPVVLTVTA AEGLRPGSLL GSVAPPEPAG
LGALTYTLVG GADPEGTFAL DAASGRLYLA RPLDFEAGPP WRALTVRAEG PGGAGARLLR
VQVRVQDENE HAPAFARDPL ALALPENPEP GAALYTFRAS DADGPGPNSD VRYRLLRQEP
PVPALRLDAR TGALSAPRGL DRETTPALLL LVEAIDRPAN ASRRRAARVS ARVFVTDEND
NAPVFASPSR VRLPEDQPPG PAALHVVARD PDLGEAARVS YRLASGGDGH FRLHSSTGAL
SVVQPLDREQ RAEHVLTVVA SDHGSPPRSA TQVLTVSVAD VNDEAPTFQQ QEYSVLLREN
SPPGTSLLTL RATDPDLGAN GQVTYGGVSS GSFSLDPDTG VLTTLRALDR EEQEEINLTV
YAQDRGSPPQ LTHATVRVAV EDENDHAPTF GSTHLSLEVP EGQDPQTLTM LRASDPDVGA
NGQLQYRILD GDPSGAFVLD LASGEFGTMR PLDREVEPAF QLRIEARDGG QPALSATLLL
TVTVLDANDH APAFPVPAYS VEVPEDVPAG TLLLQLQAHD PDAGANGRVT YYLGAGTAGA
FLLEPSSGEL RTAAALDREQ CPSYTFAVSA VDGAAAGPLS TTVSVTIMVR DVNDHAPTFP
TSPLRLRLPR PGPSFSTPTL ALATLRAEDR DAGANASILY RLAGTPPPGT TVDSYTGEIR
VARSPVVLGP RDRVLFIVAT DLGRPARSAT GVIIVGLQGE AEHGPRFPRT SSEAMIRENA
PPGTPIVSPR AVHAGGTNGP ITYRTFSIQP STGSRASKGS AITVLSAEGL DFEVSPRLRL
VLQAESGGAF AFTVLTLTLQ DANDNAPRFL RPHYVAFLPE SRPLEGPLLQ VEADDLDQGS
GGQISYSLAA SQLARGLFHV DPATGTITTT AILDREIWAE TRLVLMATDR GSPALVGSAT
LTVMVIDTND NRPTIPQPWE LRVSEDALLG SEIAQVTGND VDSGPVLWYV LSPSGPQDPF
SVGRYGGRVS LTGPLDFEQC DRYQLQLLAH DGPHEGRANL TVLVEDVNDN APAFSQSLYQ
VMLLEHTPPG SAILSVSATD RDSGANGHIS YHLASPADGF SVDPNNGTLF TIVGTVALGH
DGSGAVDVVL EARDHGTPGR AARATVHVQL QDQNDHAPSF TLPHYRVAVT EDLPPGSTLL
TLEATDADGS RTHAAVDYSI ISGNWGRVFQ LEPRLAEAGE SAGPGPQALG CLVLLEPLDF
ESLTQYNLTV AAADRGQPPQ SSVVPVTVTV LDVNDNPPVF TRASYRVAVP EDTPVGAELL
HVEASDADPG PHGLVRFTVS SGDPSGLFEL DESSGTLRLA HALDCETQAQ HQLVVQAADP
AGAHFALAPV TIEVQDVNDH GPAFPLNLLS TSLAENQPPG TLVTTLHAID GDAGAFGKLR
YSLLEAGPGP EGREAFALNS STGELRARVP FDYEHTESFR LLVGAADAGN LSASVTVSVL
VTGEDEYDPV FLAPTFHFQV PEGARRGHSL GHVQATDEDG GADGLVLYSL ATSSPYFGIN
QTTGALYLRV DSRAPGSGTA TTGGGGRTRR EAPRELRLEV IARGPLPGSR SATVPVTVDI
THTALGLAPD LNLLLVGAVA ASLGVVVVLA LAALVLGLVR ARSRKAEAAP GPMSQAAPLA
SGSLHKVGRE PPSPPPSEHL YHQTLPSYGG PGAGGPYPRG GSLDPSHSSG RGSAEAAEDD
EIRMINEFPR VASVASSLAA RGPDSGIQQD ADGLSDTSCE PPAPDTWYKG RKAGLLLPGA
GATLYREEGP PATATAFLGG CGLSPAPTGD YGFPADGKPC VAGALTAIVA GEEELRGSYN
WDYLLSWCPQ FQPLASVFTE IARLKDEARP CPPAPRIDPP PLITAVAHPG AKSVPPKPAN
TAAARAIFPP ASHRSPISHE GSLSSAAMSP SFSPSLSPLA ARSPVVSPFG VAQGPSASAL
STESGLEPPD DTELHI
//
