ID A0A2K6R4F1_RHIRO Unreviewed; 97 AA.
AC A0A2K6R4F1;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 32.
DE RecName: Full=Protein S100-A10 {ECO:0000256|ARBA:ARBA00018065};
DE AltName: Full=Calpactin I light chain {ECO:0000256|ARBA:ARBA00033060};
DE AltName: Full=Calpactin-1 light chain {ECO:0000256|ARBA:ARBA00033448};
DE AltName: Full=S100 calcium-binding protein A10 {ECO:0000256|ARBA:ARBA00032653};
OS Rhinopithecus roxellana (Golden snub-nosed monkey) (Pygathrix roxellana).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Colobinae; Rhinopithecus.
OX NCBI_TaxID=61622 {ECO:0000313|Ensembl:ENSRROP00000035908.1, ECO:0000313|Proteomes:UP000233200};
RN [1] {ECO:0000313|Ensembl:ENSRROP00000035908.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- FUNCTION: Because S100A10 induces the dimerization of ANXA2/p36, it may
CC function as a regulator of protein phosphorylation in that the ANXA2
CC monomer is the preferred target (in vitro) of tyrosine-specific kinase.
CC {ECO:0000256|ARBA:ARBA00003539}.
CC -!- SIMILARITY: Belongs to the S-100 family.
CC {ECO:0000256|ARBA:ARBA00007323}.
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DR RefSeq; XP_010385429.1; XM_010387127.1.
DR AlphaFoldDB; A0A2K6R4F1; -.
DR SMR; A0A2K6R4F1; -.
DR STRING; 61622.ENSRROP00000035908; -.
DR Ensembl; ENSRROT00000060366.1; ENSRROP00000035908.1; ENSRROG00000041423.1.
DR GeneID; 104681025; -.
DR KEGG; rro:104681025; -.
DR CTD; 6281; -.
DR GeneTree; ENSGT00940000154197; -.
DR OMA; ENCAISE; -.
DR OrthoDB; 619060at2759; -.
DR Proteomes; UP000233200; Unplaced.
DR GO; GO:1990665; C:AnxA2-p11 complex; IEA:Ensembl.
DR GO; GO:0045121; C:membrane raft; IEA:Ensembl.
DR GO; GO:0098797; C:plasma membrane protein complex; IEA:Ensembl.
DR GO; GO:0042803; F:protein homodimerization activity; IEA:Ensembl.
DR GO; GO:0044325; F:transmembrane transporter binding; IEA:Ensembl.
DR GO; GO:0001765; P:membrane raft assembly; IEA:Ensembl.
DR GO; GO:0051894; P:positive regulation of focal adhesion assembly; IEA:Ensembl.
DR GO; GO:0010756; P:positive regulation of plasminogen activation; IEA:Ensembl.
DR GO; GO:0051496; P:positive regulation of stress fiber assembly; IEA:Ensembl.
DR GO; GO:1900026; P:positive regulation of substrate adhesion-dependent cell spreading; IEA:Ensembl.
DR GO; GO:0072659; P:protein localization to plasma membrane; IEA:Ensembl.
DR GO; GO:0006900; P:vesicle budding from membrane; IEA:Ensembl.
DR CDD; cd05024; S-100A10; 1.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR028476; S100-A10.
DR InterPro; IPR001751; S100/CaBP7/8-like_CS.
DR InterPro; IPR013787; S100_Ca-bd_sub.
DR PANTHER; PTHR11639:SF74; PROTEIN S100-A10; 1.
DR PANTHER; PTHR11639; S100 CALCIUM-BINDING PROTEIN; 1.
DR Pfam; PF01023; S_100; 1.
DR SMART; SM01394; S_100; 1.
DR SUPFAM; SSF47473; EF-hand; 1.
DR PROSITE; PS00303; S100_CABP; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000233200};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 67..89
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 5..44
FT /note="S100/CaBP-9k-type calcium binding subdomain"
FT /evidence="ECO:0000259|SMART:SM01394"
SQ SEQUENCE 97 AA; 11203 MW; 3E8E03A6E7DD7A8D CRC64;
MPSQMEHAME TMMFTFHKFA GDKGYLTKED LRVLMEKEFP GFLENQKDPL AVDKIMKDLD
QCRDGKVGFQ SFFSLIAGLT IACNDYFVVH MKQKGKK
//
