ID A0A2K6RCG2_RHIRO Unreviewed; 336 AA.
AC A0A2K6RCG2;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Ankyrin repeat and SOCS box containing 1 {ECO:0000313|Ensembl:ENSRROP00000038706.1};
GN Name=ASB1 {ECO:0000313|Ensembl:ENSRROP00000038706.1};
OS Rhinopithecus roxellana (Golden snub-nosed monkey) (Pygathrix roxellana).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Colobinae; Rhinopithecus.
OX NCBI_TaxID=61622 {ECO:0000313|Ensembl:ENSRROP00000038706.1, ECO:0000313|Proteomes:UP000233200};
RN [1] {ECO:0000313|Ensembl:ENSRROP00000038706.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC -!- SIMILARITY: Belongs to the ankyrin SOCS box (ASB) family.
CC {ECO:0000256|ARBA:ARBA00005949}.
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DR AlphaFoldDB; A0A2K6RCG2; -.
DR STRING; 61622.ENSRROP00000038706; -.
DR Ensembl; ENSRROT00000063181.1; ENSRROP00000038706.1; ENSRROG00000042716.1.
DR GeneTree; ENSGT00940000153969; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000233200; Unplaced.
DR GO; GO:0000151; C:ubiquitin ligase complex; IEA:Ensembl.
DR GO; GO:0061630; F:ubiquitin protein ligase activity; IEA:Ensembl.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR CDD; cd03720; SOCS_ASB1; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR Gene3D; 1.10.750.20; SOCS box; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR037331; ASB1_SOCS.
DR InterPro; IPR001496; SOCS_box.
DR InterPro; IPR036036; SOCS_box-like_dom_sf.
DR PANTHER; PTHR24173:SF27; ANKYRIN REPEAT AND SOCS BOX PROTEIN 1; 1.
DR PANTHER; PTHR24173; ANKYRIN REPEAT CONTAINING; 1.
DR Pfam; PF00023; Ank; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF07525; SOCS_box; 1.
DR PRINTS; PR01415; ANKYRIN.
DR SMART; SM00248; ANK; 5.
DR SMART; SM00969; SOCS_box; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF158235; SOCS box-like; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 3.
DR PROSITE; PS50088; ANK_REPEAT; 3.
DR PROSITE; PS50225; SOCS; 1.
PE 3: Inferred from homology;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Reference proteome {ECO:0000313|Proteomes:UP000233200};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT REPEAT 81..110
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 111..143
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 144..176
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 294..336
FT /note="SOCS box"
FT /evidence="ECO:0000259|PROSITE:PS50225"
SQ SEQUENCE 336 AA; 37276 MW; 82AC278093AD5F83 CRC64;
VWGTGRPEGR EGAAGCAGRN LKEWLREQFC DHPLEHCEDT RLHDAAYVGD LQTLRSLLQE
ESYRSRINEK SVWCCGWLPC TPLRIAATAG HGNCVDFLIR KGAEVDLVDV KGQTALYVAV
VNGHLESTQI LLEAGADPNG SRHHRSTPVY HASRVGRADI LKALIRYGAD VDVNHHLTPD
VQPRFSRRLT SLVVCPLYIS AAYHNLQCFR LLLLAGANPD FNCNGPVNTQ GFYRGSPGCV
MDAVLRHGCE AAFVSLLVEF GANLNLVKWE SLGPESRGRR KVDPEALQVF KEARSVPRTL
LCLCRVAVRR ALGKNRLHLI PSLPLPDPIK KFLLHE
//
