ID A0A2K6REF2_RHIRO Unreviewed; 241 AA.
AC A0A2K6REF2;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE SubName: Full=Megakaryocyte and platelet inhibitory receptor G6b {ECO:0000313|Ensembl:ENSRROP00000039427.1};
GN Name=MPIG6B {ECO:0000313|Ensembl:ENSRROP00000039427.1};
OS Rhinopithecus roxellana (Golden snub-nosed monkey) (Pygathrix roxellana).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Colobinae; Rhinopithecus.
OX NCBI_TaxID=61622 {ECO:0000313|Ensembl:ENSRROP00000039427.1, ECO:0000313|Proteomes:UP000233200};
RN [1] {ECO:0000313|Ensembl:ENSRROP00000039427.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR RefSeq; XP_010381657.1; XM_010383355.1.
DR AlphaFoldDB; A0A2K6REF2; -.
DR STRING; 61622.ENSRROP00000039427; -.
DR Ensembl; ENSRROT00000063910.1; ENSRROP00000039427.1; ENSRROG00000043021.1.
DR GeneID; 104678141; -.
DR KEGG; rro:104678141; -.
DR CTD; 80739; -.
DR GeneTree; ENSGT00390000017793; -.
DR OMA; FICRGRQ; -.
DR OrthoDB; 4640612at2759; -.
DR Proteomes; UP000233200; Unplaced.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0005783; C:endoplasmic reticulum; IEA:Ensembl.
DR GO; GO:0005794; C:Golgi apparatus; IEA:Ensembl.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0005886; C:plasma membrane; IEA:Ensembl.
DR GO; GO:0007596; P:blood coagulation; IEA:Ensembl.
DR GO; GO:0030218; P:erythrocyte differentiation; IEA:Ensembl.
DR GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:Ensembl.
DR GO; GO:0035855; P:megakaryocyte development; IEA:Ensembl.
DR GO; GO:0009968; P:negative regulation of signal transduction; IEA:Ensembl.
DR GO; GO:0030220; P:platelet formation; IEA:Ensembl.
DR InterPro; IPR028070; G6B.
DR InterPro; IPR048308; G6B_V-set.
DR InterPro; IPR007110; Ig-like_dom.
DR PANTHER; PTHR37347; MEGAKARYOCYTE AND PLATELET INHIBITORY RECEPTOR G6B; 1.
DR PANTHER; PTHR37347:SF1; MEGAKARYOCYTE AND PLATELET INHIBITORY RECEPTOR G6B; 1.
DR Pfam; PF15096; G6B; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000233200};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 18..241
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014457786"
FT TRANSMEM 143..165
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 9..120
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
SQ SEQUENCE 241 AA; 26324 MW; 4D7AF56A2B0C49D4 CRC64;
MAVFLQLLPL LLSRAQGNQG ASLDGRPGDR VNLSCVGVSH PIRWVWAPSF PACKGLSKGR
RPILWASSSG TPTVPPLQPF VGRLRSLDSG IRRLELLLSA GDSGTFFCKG RHEDESRTVL
HVLGDRTYCK APGPSHGSLY PQLLIPLLGA GLVLGLGALG LVWWLHRRLP RQPIRPLPRF
APLVKTEPQR PVKEEEPKIP GDLDQEPSLL YADLDHLALS RPRRLSTVDP ADASTIYAVV
V
//
