ID   A0A2K6RJB8_RHIRO        Unreviewed;       621 AA.
AC   A0A2K6RJB8;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   24-JAN-2024, entry version 26.
DE   SubName: Full=LON peptidase N-terminal domain and ring finger 1 {ECO:0000313|Ensembl:ENSRROP00000041136.1};
GN   Name=LONRF1 {ECO:0000313|Ensembl:ENSRROP00000041136.1};
OS   Rhinopithecus roxellana (Golden snub-nosed monkey) (Pygathrix roxellana).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Colobinae; Rhinopithecus.
OX   NCBI_TaxID=61622 {ECO:0000313|Ensembl:ENSRROP00000041136.1, ECO:0000313|Proteomes:UP000233200};
RN   [1] {ECO:0000313|Ensembl:ENSRROP00000041136.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A2K6RJB8; -.
DR   STRING; 61622.ENSRROP00000041136; -.
DR   Ensembl; ENSRROT00000065631.1; ENSRROP00000041136.1; ENSRROG00000043780.1.
DR   GeneTree; ENSGT00440000033329; -.
DR   OMA; KYKKQGV; -.
DR   Proteomes; UP000233200; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   CDD; cd16514; RING-HC_LONFs_rpt2; 1.
DR   Gene3D; 2.30.130.40; LON domain-like; 1.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR   Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR   InterPro; IPR003111; Lon_prtase_N.
DR   InterPro; IPR046336; Lon_prtase_N_sf.
DR   InterPro; IPR015947; PUA-like_sf.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR019734; TPR_repeat.
DR   InterPro; IPR001841; Znf_RING.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   InterPro; IPR017907; Znf_RING_CS.
DR   PANTHER; PTHR23327:SF4; LON PEPTIDASE N-TERMINAL DOMAIN AND RING FINGER PROTEIN 1; 1.
DR   PANTHER; PTHR23327; RING FINGER PROTEIN 127; 1.
DR   Pfam; PF02190; LON_substr_bdg; 1.
DR   Pfam; PF13923; zf-C3HC4_2; 1.
DR   SMART; SM00464; LON; 1.
DR   SMART; SM00184; RING; 1.
DR   SMART; SM00028; TPR; 3.
DR   SUPFAM; SSF88697; PUA domain-like; 1.
DR   SUPFAM; SSF57850; RING/U-box; 1.
DR   SUPFAM; SSF48452; TPR-like; 1.
DR   PROSITE; PS51787; LON_N; 1.
DR   PROSITE; PS50005; TPR; 1.
DR   PROSITE; PS00518; ZF_RING_1; 1.
DR   PROSITE; PS50089; ZF_RING_2; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233200};
KW   TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW   ProRule:PRU00339}; Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00175}.
FT   REPEAT          127..160
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT   DOMAIN          327..365
FT                   /note="RING-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50089"
FT   DOMAIN          413..614
FT                   /note="Lon N-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51787"
FT   REGION          201..249
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        204..223
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        232..249
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   621 AA;  70617 MW;  1C561AFDC4E90527 CRC64;
     ARCRLCRDRL PPATASATDA EGTAPRPPPL AAAIAASDFR TSVVLNHLAE KWFPGQRERA
     RAAGRLGELL HQGRYREALA AACEALRAEP SDLIVKIYRA ESYAGLQEFK AAIEDLNAVL
     FQLPDWPEVY FRKGKVLYDA GVLGDALQLF LQCLALDEDF APAKLQVQKI LCDLLLPENL
     KEGLKESSWS SLPCTKNRPF DFPSVMEESQ SPSEPSPKQS EEIPEVTSEP VKGSLNRAQS
     AQSINSAETP AREDCLKRVF SEPVLSVQEK GVLLKRKLSL LEQDMIVNED GRNKLKKQGE
     TPNEVCMFSL AYGDIPEELI DVSDFECSLC MRLFFEPVTT PCGHSFCKNC LERCLDHAPY
     CPLCKESLKE YLADRRYCVT QLLEELIVKY LPDELSERKK IYDEETAELS HLTKNVPIFV
     CTMAYPTVPC PLHVFEPRYR LMIRRSIQTG TKQFGMCVSD TQNSFADYGC MLQIRNVHFL
     PDGRSVVDTV GGKRFRVLKR GMKDGYCTAD IEYLEDVKVE DEDEIKNLRE LHDLVYSQAC
     SWFQNLRDRF RSQILQHFGS MPEREENIQA TPNGPAWCWW LLAVLPVDPR YQLSVLSMKS
     LKERLTKIQH ILTYFSRDQS K
//