ID   A0A2K6RN20_RHIRO        Unreviewed;       201 AA.
AC   A0A2K6RN20;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   24-JAN-2024, entry version 26.
DE   RecName: Full=Syndecan {ECO:0000256|RuleBase:RU000649};
GN   Name=SDC4 {ECO:0000313|Ensembl:ENSRROP00000042411.1};
OS   Rhinopithecus roxellana (Golden snub-nosed monkey) (Pygathrix roxellana).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Colobinae; Rhinopithecus.
OX   NCBI_TaxID=61622 {ECO:0000313|Ensembl:ENSRROP00000042411.1, ECO:0000313|Proteomes:UP000233200};
RN   [1] {ECO:0000313|Ensembl:ENSRROP00000042411.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- FUNCTION: Cell surface proteoglycan. {ECO:0000256|RuleBase:RU000649}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479,
CC       ECO:0000256|RuleBase:RU000649}; Single-pass type I membrane protein
CC       {ECO:0000256|ARBA:ARBA00004479, ECO:0000256|RuleBase:RU000649}.
CC   -!- SIMILARITY: Belongs to the syndecan proteoglycan family.
CC       {ECO:0000256|ARBA:ARBA00005343, ECO:0000256|RuleBase:RU000649}.
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DR   RefSeq; XP_010382540.1; XM_010384238.1.
DR   AlphaFoldDB; A0A2K6RN20; -.
DR   STRING; 61622.ENSRROP00000042411; -.
DR   Ensembl; ENSRROT00000066919.1; ENSRROP00000042411.1; ENSRROG00000044358.1.
DR   GeneID; 104678848; -.
DR   KEGG; rro:104678848; -.
DR   CTD; 6385; -.
DR   GeneTree; ENSGT00940000160663; -.
DR   OMA; WVPTEPK; -.
DR   OrthoDB; 4258425at2759; -.
DR   Proteomes; UP000233200; Unplaced.
DR   GO; GO:0009986; C:cell surface; IEA:Ensembl.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0042802; F:identical protein binding; IEA:Ensembl.
DR   GO; GO:0070053; F:thrombospondin receptor activity; IEA:Ensembl.
DR   GO; GO:0060122; P:inner ear receptor cell stereocilium organization; IEA:Ensembl.
DR   GO; GO:0042130; P:negative regulation of T cell proliferation; IEA:Ensembl.
DR   GO; GO:0001843; P:neural tube closure; IEA:Ensembl.
DR   GO; GO:1903543; P:positive regulation of exosomal secretion; IEA:Ensembl.
DR   GO; GO:1903553; P:positive regulation of extracellular exosome assembly; IEA:Ensembl.
DR   GO; GO:0010762; P:regulation of fibroblast migration; IEA:Ensembl.
DR   GO; GO:0042060; P:wound healing; IEA:Ensembl.
DR   InterPro; IPR003585; Neurexin-like.
DR   InterPro; IPR001050; Syndecan.
DR   InterPro; IPR027789; Syndecan/Neurexin_dom.
DR   InterPro; IPR030479; Syndecan_CS.
DR   PANTHER; PTHR10915; SYNDECAN; 1.
DR   PANTHER; PTHR10915:SF3; SYNDECAN-4; 1.
DR   Pfam; PF01034; Syndecan; 1.
DR   SMART; SM00294; 4.1m; 1.
DR   PROSITE; PS00964; SYNDECAN; 1.
PE   3: Inferred from homology;
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180,
KW   ECO:0000256|RuleBase:RU000649};
KW   Heparan sulfate {ECO:0000256|ARBA:ARBA00023207,
KW   ECO:0000256|RuleBase:RU000649};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Proteoglycan {ECO:0000256|ARBA:ARBA00022974,
KW   ECO:0000256|RuleBase:RU000649};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233200};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU000649};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           19..201
FT                   /note="Syndecan"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5014414695"
FT   TRANSMEM        149..173
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          172..190
FT                   /note="Neurexin/syndecan/glycophorin C"
FT                   /evidence="ECO:0000259|SMART:SM00294"
FT   REGION          40..74
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   201 AA;  21829 MW;  04598B20EABD04E6 CRC64;
     MAPARLFALL LLFVGGVAES IRETEVIDPQ DLLEGQYFSG ALPDDEDVVG PGQESDDFEL
     SGSGDLGTED DLEDSTISPE VIHPLVPLDN HIPEKAGSGS QVPTETKKLE ENEVIPKRIS
     PIETSEDVSN KVSMSSTVQG SNIFERTEVL AALIVGGVVG ILFAVFLILL LMYRMKKKDE
     GSYDLGKKPI YKKAPTNEFY A
//