ID A0A2K6RQ98_RHIRO Unreviewed; 354 AA.
AC A0A2K6RQ98;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Signal regulatory protein gamma {ECO:0000313|Ensembl:ENSRROP00000043209.1};
GN Name=SIRPG {ECO:0000313|Ensembl:ENSRROP00000043209.1};
OS Rhinopithecus roxellana (Golden snub-nosed monkey) (Pygathrix roxellana).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Colobinae; Rhinopithecus.
OX NCBI_TaxID=61622 {ECO:0000313|Ensembl:ENSRROP00000043209.1, ECO:0000313|Proteomes:UP000233200};
RN [1] {ECO:0000313|Ensembl:ENSRROP00000043209.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A2K6RQ98; -.
DR STRING; 61622.ENSRROP00000043209; -.
DR Ensembl; ENSRROT00000067720.1; ENSRROP00000043209.1; ENSRROG00000044676.1.
DR GeneTree; ENSGT00960000186656; -.
DR OMA; CITRNES; -.
DR Proteomes; UP000233200; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0051716; P:cellular response to stimulus; IEA:UniProt.
DR GO; GO:0008284; P:positive regulation of cell population proliferation; IEA:Ensembl.
DR GO; GO:0050870; P:positive regulation of T cell activation; IEA:Ensembl.
DR CDD; cd05772; IgC1_SIRP_domain_2; 1.
DR CDD; cd16085; IgC1_SIRP_domain_3; 1.
DR CDD; cd16097; IgV_SIRP; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003597; Ig_C1-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR013106; Ig_V-set.
DR PANTHER; PTHR19971; SIGNAL-REGULATORY PROTEIN BETA; 1.
DR PANTHER; PTHR19971:SF6; SIGNAL-REGULATORY PROTEIN GAMMA; 1.
DR Pfam; PF07654; C1-set; 2.
DR Pfam; PF07686; V-set; 1.
DR SMART; SM00409; IG; 2.
DR SMART; SM00407; IGc1; 2.
DR SMART; SM00406; IGv; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 3.
DR PROSITE; PS50835; IG_LIKE; 3.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000233200};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 330..350
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..86
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 113..212
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 219..313
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
SQ SEQUENCE 354 AA; 38904 MW; 98C9634E9BF62AE7 CRC64;
MIQPENLLLV AVGETATLRC TVTSLLPVGP VLWFKGAGPG RELIYNQKEG HFPRVTTVSD
LTKRNNMDFS IRISSITPAD AGTYYCVKFR KGSPENVEFK SGPGTEMALR AKPSAPVVSG
PAARATPEHT VSFTCESHGF SPRDITLKWF KNGKELSDFQ TNVDPAGQSV AYSIRSTIRV
VLAPWDVRSQ VTCEVAHVTL KGDPLRGTAN LSEAIRVPPT LEVTQQPMRA GNQVNITCQV
RNFYPQRLQL TWLENGNVCR TEMASTLTEN KDGTYNWTSW LLVDTSDQRD DVVLTCQVKH
DGQLAVNKSL VLEVSAHQKD QSSDATHGPA SSLTVLLLIA VLLGPIYVPW KQKT
//
