ID   A0A2K6RRJ9_RHIRO        Unreviewed;       680 AA.
AC   A0A2K6RRJ9;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   24-JAN-2024, entry version 32.
DE   SubName: Full=Forkhead box P1 {ECO:0000313|Ensembl:ENSRROP00000043659.1};
GN   Name=FOXP1 {ECO:0000313|Ensembl:ENSRROP00000043659.1};
OS   Rhinopithecus roxellana (Golden snub-nosed monkey) (Pygathrix roxellana).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Colobinae; Rhinopithecus.
OX   NCBI_TaxID=61622 {ECO:0000313|Ensembl:ENSRROP00000043659.1, ECO:0000313|Proteomes:UP000233200};
RN   [1] {ECO:0000313|Ensembl:ENSRROP00000043659.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC       ECO:0000256|PROSITE-ProRule:PRU00089}.
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DR   RefSeq; XP_010384288.1; XM_010385986.1.
DR   AlphaFoldDB; A0A2K6RRJ9; -.
DR   Ensembl; ENSRROT00000068170.1; ENSRROP00000043659.1; ENSRROG00000044844.1.
DR   GeneID; 104680155; -.
DR   KEGG; rro:104680155; -.
DR   CTD; 27086; -.
DR   GeneTree; ENSGT00940000159892; -.
DR   OrthoDB; 5385885at2759; -.
DR   Proteomes; UP000233200; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   CDD; cd20065; FH_FOXP2; 1.
DR   Gene3D; 1.20.5.340; -; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR047412; FH_FOXP1_P2.
DR   InterPro; IPR001766; Fork_head_dom.
DR   InterPro; IPR032354; FOXP-CC.
DR   InterPro; IPR030456; TF_fork_head_CS_2.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR45796; FORKHEAD BOX P, ISOFORM C; 1.
DR   PANTHER; PTHR45796:SF3; FORKHEAD BOX PROTEIN P1; 1.
DR   Pfam; PF00250; Forkhead; 1.
DR   Pfam; PF16159; FOXP-CC; 1.
DR   PRINTS; PR00053; FORKHEAD.
DR   SMART; SM00339; FH; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS00658; FORK_HEAD_2; 1.
DR   PROSITE; PS50039; FORK_HEAD_3; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW   ProRule:PRU00089}; Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Nucleus {ECO:0000256|PROSITE-ProRule:PRU00089};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233200};
KW   Repressor {ECO:0000256|ARBA:ARBA00022491};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT   DOMAIN          468..541
FT                   /note="Fork-head"
FT                   /evidence="ECO:0000259|PROSITE:PS50039"
FT   DNA_BIND        468..541
FT                   /note="Fork-head"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00089"
FT   REGION          272..301
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          393..430
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          614..680
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        272..289
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        393..408
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        415..430
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        614..628
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   680 AA;  76442 MW;  6565C5E4A696986A CRC64;
     MFQCVFSSSV LQPHSTSCLF KHLFYHSATP ASQKQPEPIY SKKTEIQRQT VRAPFAKLFI
     FSALQVARQL LLQQQQQQQQ VSGLKSPKRN DKQPALQVPV SVAMMTPQVI TPQQMQQILQ
     QQVLSPQQLQ VLLQQQQALM LQQQQLQEFY KKQQEQLQLQ LLQQQHAGKQ PKEQQQVATQ
     QLAFQQQLLQ MQQLQQQHLL SLQRQGLLTI QPGQPALPLQ PLAQGMIPTE LQQLWKEVTS
     AHTAEETTGN NHSSLDLTTT CVSSSAPSKT SLIMNPHAST NGQLSVHTPK RESLSHEEHP
     HSHPLYGHGV CKWPGCEAVC EDFQSFLKHL NSEHALDDRS TAQCRVQMQV VQQLELQLAK
     DKERLQAMMT HLHVKSTEPK AAPQPLNLVS SVTLSKSASE ASPQSLPHTP TTPTAPLTPV
     TQGPSVITTT SMHTVGPIRR RYSDKYNVPI SSADIAQNQE FYKNAEVRPP FTYASLIRQA
     ILESPEKQLT LNEIYNWFTR MFAYFRRNAA TWKNAVRHNL SLHKCFVRVE NVKGAVWTVD
     EVEFQKRRPQ KISGNPSLIK NMQSSHAYCT PLNAALQASM AENSIPLYTT ASMGNPTLGN
     LASAIREELN GAMEHTNSNE SDSSPGRSPM QAVHPVHVKE EPLDPEEAEG PLSLVTTANH
     SPDFDHDRDY EDEPVNEDME
//