ID A0A2K6S0E1_SAIBB Unreviewed; 221 AA.
AC A0A2K6S0E1;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE RecName: Full=Interleukin-1 {ECO:0000256|RuleBase:RU003753};
GN Name=IL37 {ECO:0000313|Ensembl:ENSSBOP00000000846.1};
OS Saimiri boliviensis boliviensis (Bolivian squirrel monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Saimiriinae; Saimiri.
OX NCBI_TaxID=39432 {ECO:0000313|Ensembl:ENSSBOP00000000846.1, ECO:0000313|Proteomes:UP000233220};
RN [1] {ECO:0000313|Ensembl:ENSSBOP00000000846.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613,
CC ECO:0000256|RuleBase:RU003753}.
CC -!- SIMILARITY: Belongs to the IL-1 family. {ECO:0000256|ARBA:ARBA00010448,
CC ECO:0000256|RuleBase:RU003753}.
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DR RefSeq; XP_003942551.1; XM_003942502.2.
DR AlphaFoldDB; A0A2K6S0E1; -.
DR STRING; 39432.ENSSBOP00000000846; -.
DR Ensembl; ENSSBOT00000004245.1; ENSSBOP00000000846.1; ENSSBOG00000003781.1.
DR GeneID; 101033983; -.
DR KEGG; sbq:101033983; -.
DR CTD; 27178; -.
DR GeneTree; ENSGT00950000182943; -.
DR OrthoDB; 5087445at2759; -.
DR Proteomes; UP000233220; Unplaced.
DR GO; GO:0005615; C:extracellular space; IEA:InterPro.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0005125; F:cytokine activity; IEA:UniProtKB-UniRule.
DR GO; GO:0005149; F:interleukin-1 receptor binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006955; P:immune response; IEA:InterPro.
DR GO; GO:0006954; P:inflammatory response; IEA:InterPro.
DR GO; GO:0032715; P:negative regulation of interleukin-6 production; IEA:Ensembl.
DR GO; GO:0032720; P:negative regulation of tumor necrosis factor production; IEA:Ensembl.
DR GO; GO:0050727; P:regulation of inflammatory response; IEA:Ensembl.
DR Gene3D; 2.80.10.50; -; 1.
DR InterPro; IPR000975; IL-1_fam.
DR InterPro; IPR008996; IL1/FGF.
DR PANTHER; PTHR10078; INTERLEUKIN-1 FAMILY MEMBER; 1.
DR PANTHER; PTHR10078:SF31; INTERLEUKIN-37; 1.
DR Pfam; PF00340; IL1; 1.
DR PRINTS; PR00264; INTERLEUKIN1.
DR PRINTS; PR01357; INTRLEUKN1AB.
DR SMART; SM00125; IL1; 1.
DR SUPFAM; SSF50353; Cytokine; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000233220};
KW Secreted {ECO:0000256|RuleBase:RU003753}.
FT REGION 1..51
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 14..28
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 221 AA; 24617 MW; F464577A305B9B55 CRC64;
MLKMSFVEEN SGVKMGSEDL ERDEPQCCSE DPAGSPLEPD PSLPSTSFVH SSPKLKNLNP
KKFSIHDQDH KVLVLDSGNL IAVPDKSYIR PEIFFILPTS LSSASAEKGS PILLGVSKGE
FCLYCNKDKG QSRPSLQLKK KKLMKLADQK ESARRPFIFY RTQVGSQNLL ESVAHPGWFV
CTSCNCNEPV GVTEKHDHKK HIEFSFHPVC KPEMIPSEVS D
//
