ID   A0A2K6S3U0_SAIBB        Unreviewed;       835 AA.
AC   A0A2K6S3U0;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=Desmocollin 2 {ECO:0000313|Ensembl:ENSSBOP00000002050.1};
GN   Name=DSC2 {ECO:0000313|Ensembl:ENSSBOP00000002050.1};
OS   Saimiri boliviensis boliviensis (Bolivian squirrel monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC   Saimiriinae; Saimiri.
OX   NCBI_TaxID=39432 {ECO:0000313|Ensembl:ENSSBOP00000002050.1, ECO:0000313|Proteomes:UP000233220};
RN   [1] {ECO:0000313|Ensembl:ENSSBOP00000002050.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; A0A2K6S3U0; -.
DR   Ensembl; ENSSBOT00000011907.1; ENSSBOP00000002050.1; ENSSBOG00000010604.1.
DR   GeneTree; ENSGT01030000234624; -.
DR   Proteomes; UP000233220; Unplaced.
DR   GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR   GO; GO:0005509; F:calcium ion binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0007156; P:homophilic cell adhesion via plasma membrane adhesion molecules; IEA:InterPro.
DR   CDD; cd11304; Cadherin_repeat; 4.
DR   Gene3D; 2.60.40.60; Cadherins; 6.
DR   InterPro; IPR039808; Cadherin.
DR   InterPro; IPR002126; Cadherin-like_dom.
DR   InterPro; IPR015919; Cadherin-like_sf.
DR   InterPro; IPR020894; Cadherin_CS.
DR   InterPro; IPR014868; Cadherin_pro_dom.
DR   PANTHER; PTHR24027:SF80; CADHERIN-13; 1.
DR   PANTHER; PTHR24027; CADHERIN-23; 1.
DR   Pfam; PF00028; Cadherin; 4.
DR   Pfam; PF08758; Cadherin_pro; 1.
DR   PRINTS; PR00205; CADHERIN.
DR   PRINTS; PR01820; DESMOCOLLIN.
DR   SMART; SM00112; CA; 5.
DR   SMART; SM01055; Cadherin_pro; 1.
DR   SUPFAM; SSF49313; Cadherin-like; 6.
DR   PROSITE; PS00232; CADHERIN_1; 3.
DR   PROSITE; PS50268; CADHERIN_2; 5.
PE   4: Predicted;
KW   Calcium {ECO:0000256|ARBA:ARBA00022837, ECO:0000256|PROSITE-
KW   ProRule:PRU00043}; Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW   Cleavage on pair of basic residues {ECO:0000256|ARBA:ARBA00022685};
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233220};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        687..708
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          128..235
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
FT   DOMAIN          236..347
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
FT   DOMAIN          348..467
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
FT   DOMAIN          464..569
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
FT   DOMAIN          586..677
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
SQ   SEQUENCE   835 AA;  92344 MW;  CA7814E89D2927DD CRC64;
     MCAPLRLSAG PGHAKILIIA SEACKNVTLN VPSKLDAKKL VGRVNLKECF KSANLIHSSD
     PDFHILEDGS VYTTNTILLS LEKRSFTILL SNTENQEEKK ILVFLEHQTK VLKKRHTKEK
     VLRRAKRRWA PIPCSMLENS LGPFPLFLQQ VQSDTAQNYT IYYSIRGPGV DQEPRNLFYV
     ERDTGNLYCT RPVDREQYES FELVAFATTP DGYTPELPLP LLIKIEDEND NYPIFTEETY
     TFTILENSRV GSTVGQVCAT DKDEPDTMHT RLKYSIIGQV PPSPTLFFMH PSTGVITTTS
     SQLDRELIDK YQLKIKVQDM DGQYFGLQTT STCIINIGDV NDHLPTFTRT SYVTSVKENT
     VDVEILRVSV EDKDLVNTAN WRANYTILKG NENGNFKIVT DPKTNEGILC VVKPLNYEEK
     QQVIVQIGVV NEAPFSREAS SRSAMSTATV TVNVEDQDEG PECNPPIQTV RMKENAAVGT
     TSNGYKAYDP ETRSSSGIRY KKLTDPTGWV TVDENTGSIK VFRSLDREAE TIRNGIYNIT
     ILASDQKGRT CTGTLGIILQ DVNDNGPFIR KQQVTICKPT MSSAEIVAVD PDEPINGPPF
     DFSLESSTSE VQRMWRLEKI NDTAARLSYQ NDPAFGIYVV PITVRDRFGL SSVSSLDVTL
     CDCITENDCA FRVDPSTGGG GIQLGKWAIL AILLGIALLF CILFTLVCGA SRTSKPLKVI
     PDDLAQQNLI VSNTEAPGDD KVYSVNGFTT QTVGASAQGI CGTVGSGVNN GGQTIEMVKG
     GHQTLESCQR AGHHHTLDSC RGGRVEVDNS RCTYSEWHSF TQPRLGEESI RGHTG
//