ID A0A2K6S863_SAIBB Unreviewed; 652 AA.
AC A0A2K6S863;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE RecName: Full=Regulator of G-protein signaling 9 {ECO:0000256|ARBA:ARBA00034540};
GN Name=RGS9 {ECO:0000313|Ensembl:ENSSBOP00000003575.1};
OS Saimiri boliviensis boliviensis (Bolivian squirrel monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Saimiriinae; Saimiri.
OX NCBI_TaxID=39432 {ECO:0000313|Ensembl:ENSSBOP00000003575.1, ECO:0000313|Proteomes:UP000233220};
RN [1] {ECO:0000313|Ensembl:ENSSBOP00000003575.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004170};
CC Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004170}.
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DR AlphaFoldDB; A0A2K6S863; -.
DR Ensembl; ENSSBOT00000018805.1; ENSSBOP00000003575.1; ENSSBOG00000015723.1.
DR GeneTree; ENSGT00940000156505; -.
DR Proteomes; UP000233220; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0007186; P:G protein-coupled receptor signaling pathway; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR GO; GO:0009968; P:negative regulation of signal transduction; IEA:UniProtKB-KW.
DR GO; GO:0008277; P:regulation of G protein-coupled receptor signaling pathway; IEA:InterPro.
DR GO; GO:0007601; P:visual perception; IEA:UniProtKB-KW.
DR CDD; cd04450; DEP_RGS7-like; 1.
DR CDD; cd00068; GGL; 1.
DR CDD; cd08739; RGS_RGS9; 1.
DR Gene3D; 1.10.1240.60; -; 1.
DR Gene3D; 1.10.167.10; Regulator of G-protein Signalling 4, domain 2; 1.
DR Gene3D; 4.10.260.10; Transducin (heterotrimeric G protein), gamma chain; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000591; DEP_dom.
DR InterPro; IPR015898; G-protein_gamma-like_dom.
DR InterPro; IPR036284; GGL_sf.
DR InterPro; IPR016137; RGS.
DR InterPro; IPR047016; RGS6/7/9/11.
DR InterPro; IPR047017; RGS6/7/9/11_DHEX_sf.
DR InterPro; IPR047077; RGS9_RGS.
DR InterPro; IPR040759; RGS_DHEX.
DR InterPro; IPR036305; RGS_sf.
DR InterPro; IPR044926; RGS_subdomain_2.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR45746; LP21163P; 1.
DR PANTHER; PTHR45746:SF1; REGULATOR OF G-PROTEIN SIGNALING 9; 1.
DR Pfam; PF00610; DEP; 1.
DR Pfam; PF00631; G-gamma; 1.
DR Pfam; PF00615; RGS; 1.
DR Pfam; PF18148; RGS_DHEX; 1.
DR PRINTS; PR01301; RGSPROTEIN.
DR SMART; SM00049; DEP; 1.
DR SMART; SM01224; G_gamma; 1.
DR SMART; SM00224; GGL; 1.
DR SMART; SM00315; RGS; 1.
DR SUPFAM; SSF48097; Regulator of G-protein signaling, RGS; 1.
DR SUPFAM; SSF48670; Transducin (heterotrimeric G protein), gamma chain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50186; DEP; 1.
DR PROSITE; PS50132; RGS; 1.
PE 4: Predicted;
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW Reference proteome {ECO:0000313|Proteomes:UP000233220};
KW Sensory transduction {ECO:0000256|ARBA:ARBA00022606};
KW Signal transduction inhibitor {ECO:0000256|ARBA:ARBA00022700};
KW Vision {ECO:0000256|ARBA:ARBA00023305}.
FT DOMAIN 18..93
FT /note="DEP"
FT /evidence="ECO:0000259|PROSITE:PS50186"
FT DOMAIN 274..389
FT /note="RGS"
FT /evidence="ECO:0000259|PROSITE:PS50132"
FT REGION 465..492
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 504..548
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 507..535
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 652 AA; 73784 MW; 4A27A19736BD3579 CRC64;
SFVQDPTVNT LVKDMQNPET GVRMQSQRVL VTSVPHAMTG SDVLQWIVQR LWISNLEAQN
LGTFIVRYGY IYPLQDPKNL ILKPDGSLYR FQTPYFWPTQ QWPAEDTDYG KYSSPNYENY
NFLNQKMNYK WDFVIMQAKE QYRAGKERNK ADRYALDCQE KAYWLVHRCP PGMDNVLDYG
LDRVTNPNEV KVNQVCLYCI IMYYQQALMR STVKSSVSLG GIVKYSEQFS SNDAIMSGCL
PSNPWITDDT QFWDLNAKLV EIPTKMRVER WAFNFSELIR DPKGRQSFQY FLKKEFSGEN
LGFWEACEDL KYGDQSKVKE KAEEIYKLFL APGARRWINI DGKTMDITVK GLKHPHRYVL
DAAQTHIYML MKKDSYARYL KSPIYKEMLA KAIEPQETTK KSSTLPFMRR HLRSSPSPVI
LRQLEEEAKA REAANTVDIT QPGQHMAPSP HLTVYTGTCV PPSPSSPFSS SCRSPRKPFA
SPSRFIRRPS STICPSPIRV ALESSSGLEQ KGESSGSTAP CGSSVTESSE ASLDASWPRS
RPRAPPKARM ALSFSRFLRR GCLASPVFAR LSPKCPAVSH GRVQPLGDVG QQLPRLKSKR
VPNFFQIKMD VPTGSGTCLV DSEDAGTGES GDRATEKEVI CPWESLAEGK AG
//
