ID   A0A2K6S9L6_SAIBB        Unreviewed;       386 AA.
AC   A0A2K6S9L6;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=Carboxypeptidase B2 {ECO:0000313|Ensembl:ENSSBOP00000004068.1};
GN   Name=CPB2 {ECO:0000313|Ensembl:ENSSBOP00000004068.1};
OS   Saimiri boliviensis boliviensis (Bolivian squirrel monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC   Saimiriinae; Saimiri.
OX   NCBI_TaxID=39432 {ECO:0000313|Ensembl:ENSSBOP00000004068.1, ECO:0000313|Proteomes:UP000233220};
RN   [1] {ECO:0000313|Ensembl:ENSSBOP00000004068.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- SIMILARITY: Belongs to the peptidase M14 family.
CC       {ECO:0000256|ARBA:ARBA00005988}.
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DR   AlphaFoldDB; A0A2K6S9L6; -.
DR   Ensembl; ENSSBOT00000020214.1; ENSSBOP00000004068.1; ENSSBOG00000018312.1.
DR   GeneTree; ENSGT00940000159160; -.
DR   Proteomes; UP000233220; Unplaced.
DR   GO; GO:0004181; F:metallocarboxypeptidase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0042730; P:fibrinolysis; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   CDD; cd06246; M14_CPB2; 1.
DR   Gene3D; 3.30.70.340; Metallocarboxypeptidase-like; 1.
DR   Gene3D; 3.40.630.10; Zn peptidases; 2.
DR   InterPro; IPR033849; CPB2.
DR   InterPro; IPR036990; M14A-like_propep.
DR   InterPro; IPR003146; M14A_act_pep.
DR   InterPro; IPR000834; Peptidase_M14.
DR   PANTHER; PTHR11705:SF17; CARBOXYPEPTIDASE B2; 1.
DR   PANTHER; PTHR11705; PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B; 1.
DR   Pfam; PF00246; Peptidase_M14; 2.
DR   Pfam; PF02244; Propep_M14; 1.
DR   PRINTS; PR00765; CRBOXYPTASEA.
DR   SMART; SM00631; Zn_pept; 1.
DR   SUPFAM; SSF54897; Protease propeptides/inhibitors; 1.
DR   SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
PE   3: Inferred from homology;
KW   Carboxypeptidase {ECO:0000256|ARBA:ARBA00022645};
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Metalloprotease {ECO:0000256|ARBA:ARBA00023049};
KW   Protease {ECO:0000256|ARBA:ARBA00022670};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233220};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           23..386
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5014364207"
FT   DOMAIN          123..370
FT                   /note="Peptidase M14 carboxypeptidase A"
FT                   /evidence="ECO:0000259|SMART:SM00631"
SQ   SEQUENCE   386 AA;  44221 MW;  80F3DA6A88D9553E CRC64;
     MKLCSLAVLV AVVLFCERHV FAFQSGQVLS ALPRTSRQVQ VLRNLTTTYE IVLWQPVTAE
     LIEKKHQVHF FVNASDVDNV KTHLNESGIP SSVLLADVKD LIQQQISNDT VSPRASSSYY
     EQYHSLNEIY SWIELITERH PDMLKKIHIG SSYEKHPLYV LKVSGKEQTA KNAIWIDCGI
     HAREWISPAF CLWFIAHNRM WRKNRSYYAN NRCIGTDLNR NFASKHWCEE GASSFSCSEV
     YCGLYPESEP EVKAVASFLR RNINRIKAYI SMHSYAQHIV FPYSYNRSKT KDHEELSLVA
     SEAVRAIAKT SKNTMYTHGS GSETLYLAPG GADDWLYDLG IKYSFTIELR DTGKYGFLLP
     ERYIKPTCRE AFAAVSKIAW HVIRNV
//