ID   A0A2K6SAR3_SAIBB        Unreviewed;       588 AA.
AC   A0A2K6SAR3;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   SubName: Full=NACC family member 2 {ECO:0000313|Ensembl:ENSSBOP00000004475.1};
GN   Name=NACC2 {ECO:0000313|Ensembl:ENSSBOP00000004475.1};
OS   Saimiri boliviensis boliviensis (Bolivian squirrel monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC   Saimiriinae; Saimiri.
OX   NCBI_TaxID=39432 {ECO:0000313|Ensembl:ENSSBOP00000004475.1, ECO:0000313|Proteomes:UP000233220};
RN   [1] {ECO:0000313|Ensembl:ENSSBOP00000004475.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   RefSeq; XP_010350488.1; XM_010352186.1.
DR   AlphaFoldDB; A0A2K6SAR3; -.
DR   STRING; 39432.ENSSBOP00000004475; -.
DR   Ensembl; ENSSBOT00000020914.1; ENSSBOP00000004475.1; ENSSBOG00000018782.1.
DR   KEGG; sbq:101041193; -.
DR   GeneTree; ENSGT00940000159244; -.
DR   OMA; GMEMYRS; -.
DR   OrthoDB; 5342883at2759; -.
DR   Proteomes; UP000233220; Unplaced.
DR   GO; GO:0000785; C:chromatin; IEA:Ensembl.
DR   GO; GO:0005739; C:mitochondrion; IEA:Ensembl.
DR   GO; GO:0005730; C:nucleolus; IEA:Ensembl.
DR   GO; GO:0001227; F:DNA-binding transcription repressor activity, RNA polymerase II-specific; IEA:Ensembl.
DR   GO; GO:0042826; F:histone deacetylase binding; IEA:Ensembl.
DR   GO; GO:0042803; F:protein homodimerization activity; IEA:Ensembl.
DR   GO; GO:0044877; F:protein-containing complex binding; IEA:Ensembl.
DR   GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell population proliferation; IEA:Ensembl.
DR   GO; GO:1902231; P:positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage; IEA:Ensembl.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:Ensembl.
DR   GO; GO:0031503; P:protein-containing complex localization; IEA:Ensembl.
DR   CDD; cd18289; BTB_POZ_BTBD14A_NAC2; 1.
DR   Gene3D; 1.10.10.2590; BEN domain; 1.
DR   InterPro; IPR018379; BEN_domain.
DR   InterPro; IPR000210; BTB/POZ_dom.
DR   InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR   PANTHER; PTHR46105; AGAP004733-PA; 1.
DR   PANTHER; PTHR46105:SF2; NUCLEUS ACCUMBENS-ASSOCIATED PROTEIN 2; 1.
DR   Pfam; PF10523; BEN; 1.
DR   Pfam; PF00651; BTB; 1.
DR   SMART; SM01025; BEN; 1.
DR   SMART; SM00225; BTB; 1.
DR   SUPFAM; SSF54695; POZ domain; 1.
DR   PROSITE; PS51457; BEN; 1.
DR   PROSITE; PS50097; BTB; 1.
PE   4: Predicted;
KW   Isopeptide bond {ECO:0000256|ARBA:ARBA00022499};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233220};
KW   Ubl conjugation {ECO:0000256|ARBA:ARBA00022843}.
FT   DOMAIN          30..94
FT                   /note="BTB"
FT                   /evidence="ECO:0000259|PROSITE:PS50097"
FT   DOMAIN          351..448
FT                   /note="BEN"
FT                   /evidence="ECO:0000259|PROSITE:PS51457"
FT   REGION          240..272
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          544..588
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        241..261
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        555..569
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   588 AA;  62943 MW;  42D9132647CFD654 CRC64;
     MSQMLHIEIP NFGNTVLGCL NEQRLLGLYC DVSIVVKGQA FKAHRAVLAA SSLYFRDLFS
     GNSKSAFELP GSVPPACFQQ ILSFCYTGRL TMTASEQLVV MYTAGFLQIQ HIVERGTDLM
     FKVSSPHCDS QTAVIEDAGS EPQSPCNQLQ PAAAAAPYVV SPSVPIPLLT RVKHEAMELP
     PAAGPGLAPK RPLETGPPDG VAVASGAAVA AGAAPLKLPR VSYYGVPSLA TLIPGIQQVP
     YPQGERTSPG ASSLPTTDSP TSYHNEDEEE DDEAYDTMVE EQYGQMYIKA SGSYAVQEKP
     EPVPLESRSC VLIRRDLVAL PASLISQIGY RCHPKLYSEG DPGEKLELVA GSGVYITRGQ
     LMNCHLCAGV KHKVLLRRLL ATFFDRNTLA NSCGTGIRSS TSDPSRKPLD SRVLNAVKLY
     CQNFAPSFKE SEMNVIAADM CTNARRVRKR WLPKIKSMLP EGVEMYRTVM GSSATSAPLD
     PEFPPATAAQ VFEQRIYAER RGDAATIVAL RTDAVNVDLS TATNPAFDAG EEVDGAGSVI
     QEVAAPEPLS AGVQSPPQPF EQGGGSPSRP QTPAAVARRP EGTYAGTL
//