ID A0A2K6SDJ7_SAIBB Unreviewed; 2449 AA.
AC A0A2K6SDJ7;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Telomerase associated protein 1 {ECO:0000313|Ensembl:ENSSBOP00000005459.1};
GN Name=TEP1 {ECO:0000313|Ensembl:ENSSBOP00000005459.1};
OS Saimiri boliviensis boliviensis (Bolivian squirrel monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Saimiriinae; Saimiri.
OX NCBI_TaxID=39432 {ECO:0000313|Ensembl:ENSSBOP00000005459.1, ECO:0000313|Proteomes:UP000233220};
RN [1] {ECO:0000313|Ensembl:ENSSBOP00000005459.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR Ensembl; ENSSBOT00000022104.1; ENSSBOP00000005459.1; ENSSBOG00000019509.1.
DR GeneTree; ENSGT00940000161338; -.
DR Proteomes; UP000233220; Unplaced.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR CDD; cd00200; WD40; 2.
DR Gene3D; 1.25.40.370; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 5.
DR InterPro; IPR041452; APAF1_C.
DR InterPro; IPR025139; DUF4062.
DR InterPro; IPR045804; DUF5920.
DR InterPro; IPR007111; NACHT_NTPase.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR InterPro; IPR008850; TEP1_N.
DR InterPro; IPR008858; TROVE_dom.
DR InterPro; IPR037214; TROVE_dom_sf.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR44791:SF1; TELOMERASE PROTEIN COMPONENT 1; 1.
DR PANTHER; PTHR44791; TELOMERASE PROTEIN COMPONENT 1 TEP1; 1.
DR Pfam; PF17908; APAF1_C; 1.
DR Pfam; PF13271; DUF4062; 1.
DR Pfam; PF19334; DUF5920; 1.
DR Pfam; PF05729; NACHT; 1.
DR Pfam; PF05386; TEP1_N; 3.
DR Pfam; PF05731; TROVE; 2.
DR Pfam; PF00400; WD40; 9.
DR SMART; SM00320; WD40; 16.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50998; Quinoprotein alcohol dehydrogenase-like; 1.
DR SUPFAM; SSF140864; TROVE domain-like; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 2.
DR PROSITE; PS50837; NACHT; 1.
DR PROSITE; PS51226; TEP1_N; 3.
DR PROSITE; PS50988; TROVE; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 8.
DR PROSITE; PS50294; WD_REPEATS_REGION; 3.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000233220};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW WD repeat {ECO:0000256|PROSITE-ProRule:PRU00221}.
FT DOMAIN 361..540
FT /note="TROVE"
FT /evidence="ECO:0000259|PROSITE:PS50988"
FT DOMAIN 1026..1433
FT /note="NACHT"
FT /evidence="ECO:0000259|PROSITE:PS50837"
FT REPEAT 1619..1660
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1744..1776
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1872..1901
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1921..1962
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1967..2002
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 2062..2095
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 2104..2136
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 2373..2403
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 2334..2363
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2449 AA; 271711 MW; 92597A6D34407138 CRC64;
MEKLHGHVSA HSDILSLENR CLAMLPDLHP MEKLHEHISP HSDILSLENR CLAMLPDLKT
VEKPHGHVSA NPDILSLENR CLATLPSLKS TVSASPLLQN VQISYMMQAD LYWMNSSNCL
LSGPPSCRAQ HFSKGLGLSA CPMAPVSAAE TVQEATLGHW FYSEEKKPEE KKVAETQMPS
YSLSLGEEEV EDLAVKLTSG DCESHLEPTD QVLQEKKMAL MSLLCSTLVS EVNMKNAYNP
ILAEIFEVCS ELATLEPEFI LKRMEPPFSS RPFPRYIIFL RDEQRKFENA RDAEPEKKNP
PRFTLKKLVQ RLHIHEPAQH VQALLGYRYP SNLQLFSRSH LPGPWDSSRA GKRMKLSRPE
TWDRELSLRG NKASVWEELI ENEKLPFMAM LRNLCNLLRV GISTRHHELV LQRLQHARSV
IHSRQLPFRF LNAHDSIDAL EAQLRNQALP SPSNVTLMRQ IITRNEKNRP RRRFLCSLSR
QQLRTVMRIP VMYEQLKWEK LRVHKARQWK YDGEMLNRYR QALETAVNLS VKHSLPPLPG
RTILVYLTDA NADKLCPKSN PKGPPLNYVL LLIGMMITTA EQVDVVLCGG DTLKTAVLKP
EEGILKTAIK LQAQVQEFEE KNEWSLNTFG KYLLSLAGQR VPVDRVILFG QSMDYGMINV
AKQLYWQCVN SKCLFVGILL RRAQYLSTDS NPNDVTLSGC TDGILKFIAE HGASHLLEHV
GQMDKIFKIP PPPGKTGIQS LRPLEEDTPS PLAPVSQQGW RSIRLFISST FRDMHGERDL
LLRSVLPALQ ARAAPHHISL QGIDLRWGVT EEETRRNRQL EVCLGEVENA QLFVGILGSR
YGYVPPSYNL PDHPHFHWAQ QYPSGRSVTE MEVMQFLNRN QRQQPSAQAL MYFRDSSFLS
SVPDAWKSDF VSESEEAACR ISELKSYLSR QKGITCCRYP CEWGGVAAGR PYVGGLEEFG
QLVLQDVWNM IQKLYLQPGA LLEQPVSIPD DDLVQDTFQQ LQKPPSPARP RLLQDTVQQL
MLQHGRLSLV MGQSGQGKTA FLASLVSALQ AADGAKVAPL VFFHFSGARP DQGLALTLLR
RLCTYLHGQL KEPSALPNTY RSLVWELQQR LLPKSTESLQ HGQTLVLIID GADRLVDQNG
QLISDWIPKK LPRCVHLVLS VSSDGGLGET LEQSQGAHVV ALGPLEASAR ARLVREELAL
YGKRLEESPF NNQMRLLLVK RESGRPLYLR LVTDHLRLFT LYEQVSERLR SLPATVPLLL
QHILSTLEQE HGPDVLPQAL TTLEVTRSGL TVDQLHGVLS VWRTLPKGTN SWEEAVAAGH
SGDPYPMGPF AYLVQSLRSL LGEGPLERPG ARLYLPDGPL RTAAKRRYGK RPGLEDTAHI
LIAAQLWKTC DADASGTFRS CPPEALGDLP YHLLQSRNHG LLSKFLTSLH VVAAHLELGL
VSRLLEAHAL YASSVPKEER KLPEADVAVF RTFLRQQASI LSQYPRLLPQ QAANQPLDSP
VYRQAPLLSQ RWHLQHTLQW LNKPQTMKNH QSSSLSLAVS SSPTAVGFSA NGQRAAVGTA
NGTIYLLNLR TWQEEKSMVS GCDGISACLF LSDDTLFLTA FDGLLELWDL QHGCRVLQTK
AHQYQITGCC LSPDRRLLAT VCLGGCLKLW DTARGQLAFQ HTYPKSLNCV AFHPEGQIVA
TGSWAGSISF FQVDGLKVTK DLRAPGTSVR TLAFNVPGRV VAVGRLDSMV ELWAWREGAR
LAAFPAHHGF VAAALFLHAG CQLLTAGEDG KVQVWSGSLG RPRGYLGSLS LSPALSVALS
PDGDQVAVGY RADGIKIYKI SSGSQGAQGQ ELDVAVSALA WLSPKVLVSG AEDGSLQGWA
LKECYLQSLW LLSTHQKPVL GLAISQQLLA SASEDFTVWL WPRQLLTLPH KAEDFPCGTE
LRGHEGPVSC CSFSTDGGSL ATGGRDRGLL CWDVRTPKTP VLIRSFPACH RDWVTGCAWT
KDNLLEEHVV SVGRDGTLKV WDHQGVELTS IPAHSGPISH CAAALEPRAA GQPGSELLVV
TIGLDGATRL WHPLLVCQTH TLLGHSGPVR AAAVSETSGL LLTASEDGSV RLWQVPKEAD
DTCIPRSSAA ITAVAWAPDG SMAVSGNQAG KLILWQEAKA VATAQAPGHI GALIWSSTRT
FFVLSADEKI SEWQVKLRQG SAPGNFSLHL NRILQEDLGL LTSLGWAPDG HFLILAKADL
KLLCMKPGDA PSEIWSSYRE DPMILSTHKE YGIFVLQPKD PGVLSFLRQK ESGEFEESLN
FNINLENPSR TLISITQAKP ESESSFLCAS SDGMLWNLAK CNPEGEWTTG NIWQKKVNTP
ETQTPETDQS TRRESDASMD SETIPHLNTR QRRKIHSGSV TALHVLPELL VTASKDRDVK
IWERPSMQLL GLFQCEGSVS CLEPWLGANS TLQLAVGDMQ GNVYFLSWE
//
