ID   A0A2K6SNM8_SAIBB        Unreviewed;       424 AA.
AC   A0A2K6SNM8;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   RecName: Full=Septin {ECO:0000256|PIRNR:PIRNR006698};
GN   Name=SEPTIN8 {ECO:0000313|Ensembl:ENSSBOP00000008978.1};
OS   Saimiri boliviensis boliviensis (Bolivian squirrel monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC   Saimiriinae; Saimiri.
OX   NCBI_TaxID=39432 {ECO:0000313|Ensembl:ENSSBOP00000008978.1, ECO:0000313|Proteomes:UP000233220};
RN   [1] {ECO:0000313|Ensembl:ENSSBOP00000008978.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- FUNCTION: Filament-forming cytoskeletal GTPase.
CC       {ECO:0000256|PIRNR:PIRNR006698}.
CC   -!- SUBUNIT: Septins polymerize into heterooligomeric protein complexes
CC       that form filaments. {ECO:0000256|PIRNR:PIRNR006698}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasmic vesicle, secretory vesicle, synaptic
CC       vesicle membrane {ECO:0000256|ARBA:ARBA00004432}. Presynapse
CC       {ECO:0000256|ARBA:ARBA00034106}.
CC   -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like
CC       GTPase superfamily. Septin GTPase family.
CC       {ECO:0000256|PIRNR:PIRNR006698, ECO:0000256|RuleBase:RU004560}.
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DR   AlphaFoldDB; A0A2K6SNM8; -.
DR   Ensembl; ENSSBOT00000025740.1; ENSSBOP00000008978.1; ENSSBOG00000021236.1.
DR   GeneTree; ENSGT00940000156068; -.
DR   Proteomes; UP000233220; Unplaced.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-KW.
DR   GO; GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-UniRule.
DR   CDD; cd01850; CDC_Septin; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR030379; G_SEPTIN_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR016491; Septin.
DR   PANTHER; PTHR18884; SEPTIN; 1.
DR   PANTHER; PTHR18884:SF54; SEPTIN-8; 1.
DR   Pfam; PF00735; Septin; 1.
DR   PIRSF; PIRSF006698; Septin; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51719; G_SEPTIN; 1.
PE   3: Inferred from homology;
KW   Cytoplasm {ECO:0000256|PIRNR:PIRNR006698};
KW   Cytoskeleton {ECO:0000256|PIRNR:PIRNR006698};
KW   GTP-binding {ECO:0000256|ARBA:ARBA00023134, ECO:0000256|RuleBase:RU004560};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW   ECO:0000256|RuleBase:RU004560};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233220}.
FT   DOMAIN          36..302
FT                   /note="Septin-type G"
FT                   /evidence="ECO:0000259|PROSITE:PS51719"
FT   REGION          370..424
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        370..395
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   424 AA;  49252 MW;  F4503A43D1E71716 CRC64;
     MISFLNAEAE PRSLSLGGHV GFDSLPDQLV SKSVTQGFSF NILCVGETGI GKSTLMNTLF
     NTNFETEEAS HHEACVRLRP QTYDLQESNV QLKLTIVDAV GFGDQINKDE SYRPIVDYID
     AQFENYLQEE LKIRRSLFDY HDTRIHVCLY FITPTGHSLK SLDLVTMKKL DSKVNIIPII
     AKADTISKSE LHKFKIKIMG ELVSNGVQIY QFPTDDEAVA EINAVMNAHL PFAVVGSTEE
     VKVGNKLVRA RQYPWGVVQV ENENHCDFVK LREMLIRVNM EDLREQTHSR HYELYRRCKL
     EEMGFQDSDG DSQPFSLQET YEAKRKEFLS ELQRKEEEMR QMFVNKVKET ELELKEKERE
     LHEKFEHLKR VHQEEKRKVE EKRHELEEET NAFNRRKAAV EALQSQALHA TSQQPLRKDK
     DKKN
//