ID A0A2K6SPG1_SAIBB Unreviewed; 666 AA.
AC A0A2K6SPG1;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Zinc finger protein 180 {ECO:0000313|Ensembl:ENSSBOP00000009285.1};
GN Name=ZNF180 {ECO:0000313|Ensembl:ENSSBOP00000009285.1};
OS Saimiri boliviensis boliviensis (Bolivian squirrel monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Saimiriinae; Saimiri.
OX NCBI_TaxID=39432 {ECO:0000313|Ensembl:ENSSBOP00000009285.1, ECO:0000313|Proteomes:UP000233220};
RN [1] {ECO:0000313|Ensembl:ENSSBOP00000009285.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR AlphaFoldDB; A0A2K6SPG1; -.
DR Ensembl; ENSSBOT00000026048.1; ENSSBOP00000009285.1; ENSSBOG00000021514.1.
DR GeneTree; ENSGT00940000162315; -.
DR Proteomes; UP000233220; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd07765; KRAB_A-box; 1.
DR Gene3D; 6.10.140.140; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 12.
DR InterPro; IPR001909; KRAB.
DR InterPro; IPR036051; KRAB_dom_sf.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR23226:SF394; FI01424P-RELATED; 1.
DR PANTHER; PTHR23226; ZINC FINGER AND SCAN DOMAIN-CONTAINING; 1.
DR Pfam; PF01352; KRAB; 1.
DR Pfam; PF00096; zf-C2H2; 12.
DR SMART; SM00349; KRAB; 1.
DR SMART; SM00355; ZnF_C2H2; 12.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 7.
DR SUPFAM; SSF109640; KRAB domain (Kruppel-associated box); 1.
DR PROSITE; PS50805; KRAB; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 12.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 12.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000233220};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00042}.
FT DOMAIN 47..120
FT /note="KRAB"
FT /evidence="ECO:0000259|PROSITE:PS50805"
FT DOMAIN 327..354
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 355..382
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 383..410
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 411..438
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 439..466
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 467..494
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 495..522
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 523..550
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 551..578
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 579..606
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 607..634
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 635..662
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT COILED 130..157
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 666 AA; 75891 MW; 2364752EC735A4E8 CRC64;
MCACAGSRRE AGSGAQDFST LLCLEESMEE QDEKPPEPPK ACAQEGVNFK IVTVDFTQEE
QGTWKPAQRS LDGDIILESH RDLVSWDLPA VVGKEDSASK QNISDEEPAN GVKTECFTRN
DPWLSSYEEV GDYKDQLEEQ QEKHEIFLQE VAFTQRKAII HERVCKSDET GEKSGLNSSL
FSSPFIPIIN HFHNHVPHAK KWYLNSAVNS HQKIDDNETV RENNECGKPP QSIHLIQFTR
TQTKDKSCGL HDSVQSFCHG TPLQIHEKIH GGGKTFDFKE CGQVLNHNIS HNEQRIPVEE
SLYKCSKTSQ SSSLTQSMRN NSEEKPFECN QCGKSFSWSS HLVAHQRTHT GEKPYECSEC
GKSFSRSSHL VSHQRTHTGE KPYRCNQCGK SFSQSYVLVV HQRTHTGEKP YECNQCGKSF
RQSYKLIAHQ RTHTGEKPYE CNQCGKSFIQ SYKLIAHQRI HTGEKPYECN QCGKSFSQSY
KLVAHQRTHT GEKPFECNQC GKSFSWSSQL VAHQRTHTGE KPYECSECGK SFNRSSHLVM
HQRIHTGEKP YECSQCGKSF SQSYVLVVHQ RTHTGEKPYE CSHCGKSFRQ SSCLTQHQRT
HTGEKPFECN QCGKTFSLSA RLIVHQRTHT GEKPFTCIQC GKAFINSYKL IRHQATHTEE
KLYECN
//
