ID A0A2K6SWA5_SAIBB Unreviewed; 1277 AA.
AC A0A2K6SWA5;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Activating transcription factor 7 interacting protein {ECO:0000313|Ensembl:ENSSBOP00000011655.1};
GN Name=ATF7IP {ECO:0000313|Ensembl:ENSSBOP00000011655.1};
OS Saimiri boliviensis boliviensis (Bolivian squirrel monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Saimiriinae; Saimiri.
OX NCBI_TaxID=39432 {ECO:0000313|Ensembl:ENSSBOP00000011655.1, ECO:0000313|Proteomes:UP000233220};
RN [1] {ECO:0000313|Ensembl:ENSSBOP00000011655.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the MCAF family.
CC {ECO:0000256|ARBA:ARBA00010344}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A2K6SWA5; -.
DR STRING; 39432.ENSSBOP00000011655; -.
DR Ensembl; ENSSBOT00000028441.1; ENSSBOP00000011655.1; ENSSBOG00000022603.1.
DR GeneTree; ENSGT00530000063707; -.
DR OMA; QETIHEP; -.
DR Proteomes; UP000233220; Unplaced.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0016604; C:nuclear body; IEA:Ensembl.
DR GO; GO:0005667; C:transcription regulator complex; IEA:Ensembl.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:Ensembl.
DR GO; GO:0003714; F:transcription corepressor activity; IEA:Ensembl.
DR GO; GO:0006306; P:DNA methylation; IEA:Ensembl.
DR GO; GO:0000122; P:negative regulation of transcription by RNA polymerase II; IEA:Ensembl.
DR GO; GO:0090309; P:positive regulation of DNA methylation-dependent heterochromatin formation; IEA:Ensembl.
DR GO; GO:0045893; P:positive regulation of DNA-templated transcription; IEA:Ensembl.
DR GO; GO:0050821; P:protein stabilization; IEA:Ensembl.
DR GO; GO:0045898; P:regulation of RNA polymerase II transcription preinitiation complex assembly; IEA:Ensembl.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR026085; ATF7-int.
DR InterPro; IPR031870; ATF7IP_BD.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR PANTHER; PTHR23210; ACTIVATING TRANSCRIPTION FACTOR 7 INTERACTING PROTEIN; 1.
DR PANTHER; PTHR23210:SF22; ACTIVATING TRANSCRIPTION FACTOR 7-INTERACTING PROTEIN 1; 1.
DR Pfam; PF16788; ATF7IP_BD; 1.
DR Pfam; PF16794; fn3_4; 1.
DR SUPFAM; SSF49265; Fibronectin type III; 1.
DR PROSITE; PS50853; FN3; 1.
PE 3: Inferred from homology;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW Reference proteome {ECO:0000313|Proteomes:UP000233220};
KW Repressor {ECO:0000256|ARBA:ARBA00022491};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 1167..1277
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 108..234
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 255..381
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 401..436
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 465..576
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 665..728
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 829..869
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 893..1033
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1122..1167
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 108..130
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 157..185
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 196..214
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 315..354
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 363..381
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 419..433
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 548..576
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 682..728
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 829..843
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 893..973
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 989..1009
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1010..1024
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1139..1157
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1277 AA; 137349 MW; 60C43BF656673E45 CRC64;
MHEDQRFKME SLEEPQKKVF KARKTMRVSD RQQLEAVYKV KEELLKTDVK LLNGNHENGD
LDPTSPLENV DYIKDKEEVN GIEEICFDPE ESKTEWKETP CILSVNVKNK QDDDLNSEPL
SPNNVTLEPE SKLTAEPVSG DPAPGDLDAG DPASGVLASG DSTSDDPASG DPTSSDPSSS
DAASGDAPSD DVPSGDATSA DATSDLSSGA PTSSDPLPGE PVSVAPISGD CASDDIASSE
ITSVDLASGA QASIDPASDD LASGELSSSE LASDDLATGE LASDELTSES AFDRTFEPSS
VPVCEPVPEI DNIEPSSNKD GDFLEKNGDD EKLEQIQSKD SLDEKNKADS NIDTNEETLE
TDDTTICSDR PPENEKKVEE DTITELALGE DAISSSMEID QVEKNEDENS ADLVGSISEN
VTEDDKSENI LENTDSMETD EIIPILEKLA PSEDELTCFS KASLLPIDET NPDLEEKMES
SFGSPSKQES SESLPKEAFL VLSDEEDISG EKDESEVISQ NETCSPAEVE SNEKDNKPEE
EEQVTHEDDE RPSEKNEFSR RKRSKSEDMD NIQSKRRRYM EEEYEAEFQV KITAKGDINQ
KLQKVIQWLL EEKLCALQCA VFDKTLAELK TRVEKIECNK RHKTVLTELQ AKIARLTKRF
EAAKEDLKKR QEHPPNPPVS PGKTVNDVNS NNNMPYRNAG TVRQMLESKR NVSESAPPSF
QTPVNTVSST NLVTPPTVVS SQPKLQTPVT SGSLTATSVL PAPNTAAVVA TTQVPSGNPQ
PTISLQSLPV ILHVPVAVSS QPQLLQSHPG TLVTNQPSGN VEFISVQSPP TVSGLTKNPV
SLPSLPNPTK PNNVPSVPSP SIQRNPTASA APLGTTLAVQ AVPTAHSIVQ ATRTSLPTVG
PSGLYSPSNN RGPIQMKIPI SAFSTSSPAE QNSTTTARIE NQTNKTIDVS VNKKAADSTS
QSGKATGSDS SGVIDLTMDD EESGASQDSK KLNHTPVSTM SSSQPVSRPL QPIQPAPPLQ
PSGVPTSGPS QTTIHLLPTA PTTVNVTHRP VTQVTTRLPV PRAPANHQVV YTTLPAPPAQ
APLRGTVMQA PAVRQVNPQN SVTVRVPQTT TYVVNNGLTL GSTGPQLTVH HRPPQVHTEP
PRPVHPAPLP EAPQPQRLPP EAASTSLPQK PHLKLARVQS QNGIVLSWSV LEVDRSCATV
DSYHLYAYHE EPSATVPSQW KKIGEVKALP LPMACTLTQF VSGSKYYFAV RAKDIYGRFG
PFCDPQSTDV ISSTQSS
//
