ID A0A2K6T4X7_SAIBB Unreviewed; 1215 AA.
AC A0A2K6T4X7;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Immunoglobulin superfamily member 3 {ECO:0000313|Ensembl:ENSSBOP00000014695.1};
GN Name=IGSF3 {ECO:0000313|Ensembl:ENSSBOP00000014695.1};
OS Saimiri boliviensis boliviensis (Bolivian squirrel monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Saimiriinae; Saimiri.
OX NCBI_TaxID=39432 {ECO:0000313|Ensembl:ENSSBOP00000014695.1, ECO:0000313|Proteomes:UP000233220};
RN [1] {ECO:0000313|Ensembl:ENSSBOP00000014695.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
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DR RefSeq; XP_003933568.1; XM_003933519.2.
DR AlphaFoldDB; A0A2K6T4X7; -.
DR STRING; 39432.ENSSBOP00000014695; -.
DR Ensembl; ENSSBOT00000031493.1; ENSSBOP00000014695.1; ENSSBOG00000024073.1.
DR GeneTree; ENSGT00940000155177; -.
DR OrthoDB; 5347942at2759; -.
DR Proteomes; UP000233220; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0032808; P:lacrimal gland development; IEA:Ensembl.
DR CDD; cd00099; IgV; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 8.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR013106; Ig_V-set.
DR PANTHER; PTHR12207:SF21; IMMUNOGLOBULIN SUPERFAMILY MEMBER 3; 1.
DR PANTHER; PTHR12207; V-SET AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF07686; V-set; 4.
DR SMART; SM00409; IG; 8.
DR SMART; SM00408; IGc2; 4.
DR SMART; SM00406; IGv; 4.
DR SUPFAM; SSF48726; Immunoglobulin; 7.
DR PROSITE; PS50835; IG_LIKE; 8.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000233220};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..1215
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014377021"
FT TRANSMEM 1145..1168
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 6..138
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 159..248
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 276..386
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 416..534
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 579..668
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 696..823
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 833..965
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 969..1118
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 1019..1050
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1028..1048
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1215 AA; 137527 MW; 8E683A90EAE56548 CRC64;
MKCFFPVLSC LAVLGVVSAQ RQVSVQEGPL YRTEGSHITI WCNVSGYQGP SEQNFQWSIY
LPSAPEREVQ IVSTVDSSFP YAIYTQRVRG GKIFIERVQG NSALLHITDL QARDAGEYEC
HTPNTDDRYF GSYSAKMNLV VILDSLQTTA MPQTLHRVEQ DPLELTCEVS SETVQHSHLS
VAWLRQKGGE KPVEVISLSR DFVLQSSSEY AQRQSLGEVR LDKLGKTTFR LTIFHLQPSD
QGEFYCEAAE WIQDPDGSWY AMTRKRSEGA VVNVQPTDKE FTVRLETEKR LHTVGEPVEF
RCILEAQNVP DRYFAVSWAF NSSLIATMGP NAVPALNSEF AHREARGQLK VAKESDSVFV
LKIYHLRQED SGKYNCRVTE REKTVTGEFI DKESKRPKNI PIIVLPLTDN WVVKVPQHHQ
ILSQGHLESS ISVEVASNAS VILEGEDLHF SCSVRTAGRP QGRFSVIWQL VDRQNRRSNI
MWLDRDGTMQ PGSSYWERSS FGGVQMEQVQ PNSFSLGIFN SRKEDEGQYE CHVTEWVRAV
DGEWQIVGER RASTLISITA LEMGFAVTAI SRTPGVTYSD SFDLQCIIKP HYPARVPVSV
TWRFQPVGTV EFHDLVTFTR DGGVQWGDRS SSFRTRTAIE KAEFSNNVRL SISRASDTEA
GKYQCVAELW RKNYNNTWTR LAERASNLLE IRVLQPVTKL QVSKSKRTLT LVENRPIQLN
CSVKSQTSQN SHFAVLWYVH KPSDADGKLI LKTTHNSAFE YGTYAEEEGL RARLQFERHV
SGGLFSLTVQ RAEVSDSGSY YCHVEEWLLS PNYAWYKLAE EVSGRTEVTV KQPDSRLRLS
QAQGNLSVLE TWQVQLECVV LNRTSMASQL MVEWFVWKPN HPEQETVARL SREATFHYGE
QAAKNNLKGR LHLESPSPGV YRLFIQNVAV QDSGTYSCRV EEWLPSPSGV WYKRAEDTAG
QTALTVMRPD AALQVDTVVP NATVSEKAAF QLDCSIVSRS SQDSRFAVAW YSLRTKAGAK
RSSPDVEEQE EEMEEEEEEE EEEDSDDATE RTALLSVGPD AVFGPEGSPW EGRLRFQRLS
PVLYRLTVLQ ASPQDTGNYS CRVEEWLPSP QKEWYRLTEE ESAPIGIHVL DTSPTLQSII
CSNDALFYFV FFYPFPIFGI LIITILLVRF KSRNSSKNSD GKNGVPLLWI KEPHLNYSPT
CLEPPVLSIH PGAID
//
