ID   A0A2K6T546_SAIBB        Unreviewed;       553 AA.
AC   A0A2K6T546;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   24-JAN-2024, entry version 20.
DE   SubName: Full=Isthmin 2 {ECO:0000313|Ensembl:ENSSBOP00000014756.1};
GN   Name=ISM2 {ECO:0000313|Ensembl:ENSSBOP00000014756.1};
OS   Saimiri boliviensis boliviensis (Bolivian squirrel monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC   Saimiriinae; Saimiri.
OX   NCBI_TaxID=39432 {ECO:0000313|Ensembl:ENSSBOP00000014756.1, ECO:0000313|Proteomes:UP000233220};
RN   [1] {ECO:0000313|Ensembl:ENSSBOP00000014756.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the isthmin family.
CC       {ECO:0000256|ARBA:ARBA00010198}.
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DR   AlphaFoldDB; A0A2K6T546; -.
DR   STRING; 39432.ENSSBOP00000014756; -.
DR   Ensembl; ENSSBOT00000031554.1; ENSSBOP00000014756.1; ENSSBOG00000024120.1.
DR   GeneTree; ENSGT00940000162809; -.
DR   Proteomes; UP000233220; Unplaced.
DR   Gene3D; 2.20.100.10; Thrombospondin type-1 (TSP1) repeat; 1.
DR   InterPro; IPR005533; AMOP_dom.
DR   InterPro; IPR000884; TSP1_rpt.
DR   InterPro; IPR036383; TSP1_rpt_sf.
DR   PANTHER; PTHR10239; ISTHMIN-2; 1.
DR   PANTHER; PTHR10239:SF28; ISTHMIN-2; 1.
DR   Pfam; PF03782; AMOP; 1.
DR   Pfam; PF00090; TSP_1; 1.
DR   SMART; SM00723; AMOP; 1.
DR   SMART; SM00209; TSP1; 1.
DR   SUPFAM; SSF82895; TSP-1 type 1 repeat; 1.
DR   PROSITE; PS50856; AMOP; 1.
DR   PROSITE; PS50092; TSP1; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000233220};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..25
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           26..553
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5014402152"
FT   DOMAIN          377..541
FT                   /note="AMOP"
FT                   /evidence="ECO:0000259|PROSITE:PS50856"
FT   REGION          41..61
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          204..284
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        229..264
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        265..281
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   553 AA;  62208 MW;  AFB8723B624EB569 CRC64;
     IRTTQTASMC VPCLVIILGM RKLTAGPITN PGLVCGEPGS PLSFASASPD PKSPKEEEEG
     PLLPRTHLQA EPHQQERWTL TEPAALTLGH ATPPRTPEVT PLLLELQKLP GLVNTALSTP
     NPDIQVRELQ KGQQPLRHPE RRGLRGWTQD SLHLGLCGRW GFCVGSEDRL PCSLSGVAGR
     QGCVSTSEWE MLCGLQGIPG IWGGFPEKTR GSNPHPDPTP YLASLGEEEG GTHLKDRAPG
     EQEEKREEKE EDKDYSVEEI KDLDQEDKKE DDDEEEELWF NGTTDNWDQG RLFPRAWVLK
     EFNIKDHETQ EEWSPWSPCS GNCSAGKQQR TRSCGYSCTS IESRSCELPF CSDTEDKNIS
     GPLSEEWQLL NKSATDLFGQ DVDSCEKWLT CKNDFLTNYV SQMQRDLPSC PCVYPRGAIE
     RTVSMRDNQR QGRRYRWRDA SGHSERLDIY HPTARYCLRS LLSEESSTLG AQHCCYDNHR
     RLLTRGKGAG APNLISPQLS PQLHFKVDTL PWILCKGDWS RLHAVRPPNN DRACPDNPPL
     EEYLAQLQEA KEY
//