ID A0A2K6T5K0_SAIBB Unreviewed; 624 AA.
AC A0A2K6T5K0;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Autophagy related 16 like 1 {ECO:0000313|Ensembl:ENSSBOP00000014916.1};
GN Name=ATG16L1 {ECO:0000313|Ensembl:ENSSBOP00000014916.1};
OS Saimiri boliviensis boliviensis (Bolivian squirrel monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Saimiriinae; Saimiri.
OX NCBI_TaxID=39432 {ECO:0000313|Ensembl:ENSSBOP00000014916.1, ECO:0000313|Proteomes:UP000233220};
RN [1] {ECO:0000313|Ensembl:ENSSBOP00000014916.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the WD repeat ATG16 family.
CC {ECO:0000256|ARBA:ARBA00009271}.
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DR RefSeq; XP_010345511.1; XM_010347209.1.
DR AlphaFoldDB; A0A2K6T5K0; -.
DR STRING; 39432.ENSSBOP00000014916; -.
DR Ensembl; ENSSBOT00000031714.1; ENSSBOP00000014916.1; ENSSBOG00000024084.1.
DR GeneID; 101052514; -.
DR CTD; 55054; -.
DR GeneTree; ENSGT00940000153936; -.
DR OrthoDB; 458014at2759; -.
DR Proteomes; UP000233220; Unplaced.
DR GO; GO:0034274; C:Atg12-Atg5-Atg16 complex; IEA:Ensembl.
DR GO; GO:0000421; C:autophagosome membrane; IEA:Ensembl.
DR GO; GO:0005930; C:axoneme; IEA:Ensembl.
DR GO; GO:0036020; C:endolysosome membrane; IEA:Ensembl.
DR GO; GO:0034045; C:phagophore assembly site membrane; IEA:Ensembl.
DR GO; GO:0097225; C:sperm midpiece; IEA:Ensembl.
DR GO; GO:0120095; C:vacuole-isolation membrane contact site; IEA:Ensembl.
DR GO; GO:0051020; F:GTPase binding; IEA:Ensembl.
DR GO; GO:0042802; F:identical protein binding; IEA:Ensembl.
DR GO; GO:0043495; F:protein-membrane adaptor activity; IEA:Ensembl.
DR GO; GO:0022038; P:corpus callosum development; IEA:Ensembl.
DR GO; GO:0051607; P:defense response to virus; IEA:Ensembl.
DR GO; GO:0021766; P:hippocampus development; IEA:Ensembl.
DR GO; GO:0016237; P:microautophagy; IEA:Ensembl.
DR GO; GO:0039689; P:negative stranded viral RNA replication; IEA:Ensembl.
DR GO; GO:0010508; P:positive regulation of autophagy; IEA:Ensembl.
DR GO; GO:0034497; P:protein localization to phagophore assembly site; IEA:Ensembl.
DR GO; GO:0098792; P:xenophagy; IEA:Ensembl.
DR CDD; cd22887; Atg16_CCD; 1.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR045160; ATG16.
DR InterPro; IPR013923; Autophagy-rel_prot_16_dom.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR19878; AUTOPHAGY PROTEIN 16-LIKE; 1.
DR PANTHER; PTHR19878:SF6; AUTOPHAGY-RELATED PROTEIN 16-1; 1.
DR Pfam; PF08614; ATG16; 1.
DR Pfam; PF00400; WD40; 5.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00320; WD40; 7.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 2.
DR PROSITE; PS50082; WD_REPEATS_2; 6.
DR PROSITE; PS50294; WD_REPEATS_REGION; 4.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000233220};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT DOMAIN 16..206
FT /note="Autophagy-related protein 16"
FT /evidence="ECO:0000259|Pfam:PF08614"
FT REPEAT 335..368
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 379..420
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 421..462
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 479..501
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 557..588
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 590..624
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 292..323
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 82..230
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 624 AA; 70043 MW; 89BFE8BD804637FD CRC64;
MSSGLRASDF PRWKRHISEE LRRRDRLQRQ AFEEIILQYN KLLEKSDLHS VLAQKLQAEK
HDVPNRHEIS PGHDGTWNDS QLQEMAQLRI KHQEELTELH KKRGELAQLV IDLNNQMQQK
DREMQMNEAK IAECLQTISD LETECLDLRT KLQDLEIANQ TLKDEYDALQ ITFTALEEKL
RKTTEENQEL VTRWMAEKAQ EANRLNAENE KDSRRRQARL QKELAEAAKE PLPVEQDDDI
EVIVDETSDH TEETSPVRAI SRAATKRLSQ PAGGLLDSIT NIFGLSESPL LGHHSSSDAA
RRRSVSSFPV PQDNVDTHPG SGKEVRVPTT ALCVFDAHDG EVNAVQFSPG SRLLATGGMD
RRVKLWEVFG EKCEFKGSLS GSNAGITSIE FDSAGSYLLA ASNDFASRIW TVDDYRLRHT
LTGHSGKVLS AKFLLDNARI VSGSHDRTLK LWDLRSKVCI KTVFAGSSCN DIVCTEQCVM
SGHFDKKIRF WDIRSESIVR EMELLGKITA LDLNPERTEL LSCSRDDLLK VIDLRTNAVK
QTFSAPGFKC GSDWTRVVFS PDGSYVAAGS AEGSLYIWSV LTGKVEKVLS KQHSSSINAV
AWSPSGSHVV SVDKGCKAVL WAQY
//
