ID A0A2K6T823_SAIBB Unreviewed; 3115 AA.
AC A0A2K6T823;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 10-FEB-2021, entry version 15.
DE SubName: Full=Centromere protein F {ECO:0000313|Ensembl:ENSSBOP00000015785};
GN Name=CENPF {ECO:0000313|Ensembl:ENSSBOP00000015785};
OS Saimiri boliviensis boliviensis (Bolivian squirrel monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Saimiriinae; Saimiri.
OX NCBI_TaxID=39432 {ECO:0000313|Ensembl:ENSSBOP00000015785, ECO:0000313|Proteomes:UP000233220};
RN [1] {ECO:0000313|Ensembl:ENSSBOP00000015785}
RP NUCLEOTIDE SEQUENCE.
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lindblad-Toh K.;
RT "The Draft Genome of Saimiri boliviensis.";
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSBOP00000015785}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (FEB-2018) to UniProtKB.
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DR RefSeq; XP_003930404.1; XM_003930355.2.
DR Ensembl; ENSSBOT00000032588; ENSSBOP00000015785; ENSSBOG00000024619.
DR GeneID; 101049170; -.
DR KEGG; sbq:101049170; -.
DR CTD; 1063; -.
DR GeneTree; ENSGT00730000111187; -.
DR OMA; YNAQLVQ; -.
DR OrthoDB; 205405at2759; -.
DR Proteomes; UP000233220; Unplaced.
DR GO; GO:0005930; C:axoneme; IEA:Ensembl.
DR GO; GO:0005813; C:centrosome; IEA:Ensembl.
DR GO; GO:0036064; C:ciliary basal body; IEA:Ensembl.
DR GO; GO:0097539; C:ciliary transition fiber; IEA:Ensembl.
DR GO; GO:0000940; C:condensed chromosome outer kinetochore; IEA:Ensembl.
DR GO; GO:0030496; C:midbody; IEA:Ensembl.
DR GO; GO:0005635; C:nuclear envelope; IEA:Ensembl.
DR GO; GO:0016363; C:nuclear matrix; IEA:Ensembl.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0045120; C:pronucleus; IEA:Ensembl.
DR GO; GO:0000922; C:spindle pole; IEA:Ensembl.
DR GO; GO:0070840; F:dynein complex binding; IEA:Ensembl.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0008022; F:protein C-terminus binding; IEA:Ensembl.
DR GO; GO:0042803; F:protein homodimerization activity; IEA:Ensembl.
DR GO; GO:0008134; F:transcription factor binding; IEA:Ensembl.
DR GO; GO:0001822; P:kidney development; IEA:Ensembl.
DR GO; GO:0051310; P:metaphase plate congression; IEA:Ensembl.
DR GO; GO:0000278; P:mitotic cell cycle; IEA:Ensembl.
DR GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:Ensembl.
DR GO; GO:0015031; P:protein transport; IEA:Ensembl.
DR GO; GO:0010389; P:regulation of G2/M transition of mitotic cell cycle; IEA:Ensembl.
DR GO; GO:0016202; P:regulation of striated muscle tissue development; IEA:Ensembl.
DR GO; GO:0021591; P:ventricular system development; IEA:Ensembl.
DR InterPro; IPR043513; Cenp-F.
DR InterPro; IPR018302; CenpF/LEK1_Rb-prot-bd.
DR InterPro; IPR019513; Centromere_CenpF_leu-rich_rpt.
DR InterPro; IPR018463; Centromere_CenpF_N.
DR PANTHER; PTHR18874; PTHR18874; 2.
DR Pfam; PF10490; CENP-F_C_Rb_bdg; 1.
DR Pfam; PF10473; CENP-F_leu_zip; 2.
DR Pfam; PF10481; CENP-F_N; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000233220}.
FT DOMAIN 1..307
FT /note="CENP-F_N"
FT /evidence="ECO:0000259|Pfam:PF10481"
FT DOMAIN 2132..2271
FT /note="CENP-F_leu_zip"
FT /evidence="ECO:0000259|Pfam:PF10473"
FT DOMAIN 2314..2453
FT /note="CENP-F_leu_zip"
FT /evidence="ECO:0000259|Pfam:PF10473"
FT DOMAIN 2970..3014
FT /note="CENP-F_C_Rb_bdg"
FT /evidence="ECO:0000259|Pfam:PF10490"
FT REGION 125..161
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 192..261
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1661..1693
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1719..1741
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2892..2961
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2988..3115
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 164..191
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 280..384
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 386..413
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 418..466
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 477..497
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 523..615
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 623..720
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 832..873
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 899..989
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1029..1056
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1082..1120
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1132..1159
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1196..1244
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1293..1313
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1397..1417
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1549..1612
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1624..1646
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1792..1861
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1899..1968
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2003..2079
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2108..2135
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2143..2198
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2206..2279
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2297..2317
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2325..2359
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2367..2468
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2476..2555
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2563..2604
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2619..2685
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2690..2717
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2719..2739
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2754..2830
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2837..2864
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2872..2892
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 130..161
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1665..1693
FT /note="Polyampholyte"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2917..2956
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3000..3014
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3030..3077
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 3115 AA; 357659 MW; 3C4251D8423EFC7C CRC64;
MSWALEEWKE GLPTRALQKI QELEGQLDKL KKEKQQRQFQ LDSLEAALQK QKQKVENEKT
EGTNLKRENQ RLIEICESLE KTKQKISHEL QVKESQVNFQ EGQLNSGKKQ IEKLEQELKR
CKSELERSQR AAQSADGSLN PCNTPQQIST TPLTPSQYYS GSKYEDLKEK YNKEVEERKR
LEAEVKAFQA KKANQTLPQT SMNHRDIARH QASSSVFSWQ QDKTPSRLSS SSQKTPIRRD
TSASYFSGEQ EMTPSQSTLQ IGKRDANSSF FDNSNSPHLL DQLKVQNQEL RSKINELELR
LQGQEKEMKS QVNKFQELQL QLEKAKVELI EKEKVLNKCR DELVRTTAQY DQASTKCTAL
EQKLKKLTED LSCQRQNAES ARCSLEQKIK EKEKEFQEEL SRQQRSFQTL DQESIQMKAK
LTQELQQAKN MHNVLQAELD KVTSVKQQLE KNVEEFKQKL CRAEQAFQAS EVKESELRRS
TEEMKKENSL LKSQSEQTAR EVCHLEAELK KVKQCLNQSQ NFAEEMKVKN TSQETMLRDL
QEKINQQENC LTLEKLKLAV ADLEKQRDCS QDLLKKREHH IEQLNDKLNK TEKESKALLS
ALELKKKEYE ELKEEKTLFS CWKSENEKLL TQMESEKESL QSKINHLETC LKTQQIKSHE
YNERVRTLEM ERENLSVEIR NLHNVIDSKS VEVETQKQAY EELQQKAEFS DQKHQKEIEN
MCLKTFQLTG QVEDLEHKLQ LLSNEIMDKD RCYQDLHTEY ESLRDLLKSK DASLVTNEVH
QRSLLAFDQL LAMHNSFANI IGEQGSMPSE RSECHLDANQ SPKNSAILQN RVDSLEFSLE
SQKQMNSDLQ KQCEELVQIK GEIEENLMRA EQMHQSFVAE TSQRINKLQE DTSAHQNVVA
ETLSALENKE KELQLLNGKL ETEQAEIQEL KKSNHLLEDS LKELQLLSET LSMEKKEMSS
IISLNKREIE ELTQENGSLK EINASLNQEK MNLIQKSESF ANCINEREKS ISELSDQYNQ
EKLILLQRCE ETGNAYEDLS QKYKAAQEKN FKLESLLNEC TTLCEHRKND LEQLKEAFAK
EHQEFLTKLA FAEERNQNLI LELETVQQDL RSEMTDIQNN SKNEADGLKP EIMTLKEEQN
KMQKEVNDLL QENEQLMKLM KTEHECQNLA LEPIRNSMKE RESERNQCNF KLQMNLEVKE
ISLDSYNAQL VQLEAMLRNM ELKLKESEKE KECLQNELQT IRGKLETRNL QDMQSQEISG
LKDCEIDAEE KHISVLRELS TTQNDNGHLQ CSLETAVNKL NELEKMCEKL QTDKCELVSE
LNESRSGCIT ATRKMAEEVG KLVNEVKILN DDSGLLHGEL MEGIPGGEFG EQSNEQHPVS
LATLDDSNFC EHLALSNKEV QMHFAELQEK FSSLQSEHKI LHDQHCQMSS KMLELQTYVD
SLKAENLVLS TNLRNFQGDL VKEMQPGLKE GLVPSLSSSC LPVSPSLSSL GDCSFYKALL
EQTGEMSLLN NLEGNVSANQ SSVDEVFCNS LEEENLTKKE IPLAPMKSVE ELESLCQVYQ
QSLEKLEEKM ESQEIMKNKE IQELEQLLSS ERQELDCLRK RYLSENEQWQ QKLTSVTLEM
ESKLAAEKKQ TEQLSLELEV ARLQLQGLDL SSRSLLGIDT EDAIQGRNES GDIKESKEHT
SETTEGTPKH DAHHMCDKDV QQDLSLDIEK ITETGAVKLT GECSGEQSPD TSYETPREDK
TQGYSECISE LSFSGTNALV PVGFPGNQEN TQNLQLQVKE ISNENLRLLH VIEDRDRKVE
SLLNEMNELD SKLHLQEVQL MTKIEACIEL EKIVEELKKE NTDLSEKLES ISCDNQELLQ
RVETSEGLNS NLEMCADKSS HEDIEDNAAK VNYSWKERFL DVENELSRIR SEKARIEHQA
LSLEAALERV QIEKLCLEKD NENKQKVIVC LEEDLSVVTR ERDQLRGELD STSKKTLKLD
QLSEKMEKTQ ELESHQSECL RCLQVAEAEV KEKTELLQTL SSDVSELLKE KTHLQEKLQS
LEKDSQALSL AKCELENQIA QLNEEKELLV KESESLQARL SESDYEKLNV SKALEAALVE
KGEFALRLSS TQEEVHQLRR GIEKLRVRIE ADEKKQLHVA EKLKEREREN DSLKDKVENL
ERELQMSEEN QELVILDAEN SKAEVETLKT QLEETARSLK VFELDHVMLR SEKENLAKQL
QEKQGQVSEL DKLLSSFKSL LEEKEQAEIQ VKEESKTAAE MLQNQLKELN DAVAALCGDQ
ETVKATEQSL DSPVEEVHQL RNSIEKLRVH LEADEKKQLC VLEQLKESEH EADLLKGRME
NLERELELSR KNQEHAVLEA ENSKGEVDTL KAKIEGMTQS LRDLELDLVT IRSEKENLTN
ALQKEQERIS ELEIINSSFE NILQEKEQEK VQMKEKSNTA VEMLQTQLRE LNERVAALHN
DQETCKAKEQ NLSSQVDCLE LEKAQLLQGL EEAKNNYIVL QSSVNGLIQE VEDGKQKLEK
KDEEISRLKN QIQDQEQLIS KLSEVEGEHQ LLKKQNLELV NLTVELEQKI QVLQSKNASL
QDTLEVLQSS YKSLENELEL TKMDKMSFVE KVNTMTAKET ELQREMHEMA QKTAELQEEL
NGEKNRLTGE LQLLLEEIKS SKDQLKELTL ENSELKKSLD CMHEDQVEKE GKVREEIAEY
QLRLHEAEKK HQAVLLDTNK QYEIEIQTYQ EKLSSKEECL TSQKLEMDLL KSSKEELSNS
LKATTQVLEE LKKTKMDHLK YVNQLKKENE HAQGKIKLLM KSCKQLEEEK ETLQKELSQL
EAAQERQKTG AILDAKVDEF MTEIKELKET LEEKTKEADE YLDKYCSLLI RHEKLEKAKE
MLETQVAHLC SQQSKQDFRG SPLLDGAVPE PSPMPSATEK RLSSGPNKAS GKRQRSSGIW
ENGRGPTPST PETFSKKSKK AVMRGIHPAK DTEDTEFEPE GLPEVVKKGF ADIPTGKTSP
YILRRTTMAT RTSPRLAAQK LALSPLSLGK ENLAESSKPT AGGSRSQKVK VAQQSPVDSG
TVLQEPTTKS LLVNNLPERS PADSPKEGLR AKRGRLTPSP KAGVEPKGSE NCKVQ
//
