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Database: UniProt
Entry: A0A2K6T823_SAIBB
LinkDB: A0A2K6T823_SAIBB
Original site: A0A2K6T823_SAIBB 
ID   A0A2K6T823_SAIBB        Unreviewed;      3115 AA.
AC   A0A2K6T823;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   10-FEB-2021, entry version 15.
DE   SubName: Full=Centromere protein F {ECO:0000313|Ensembl:ENSSBOP00000015785};
GN   Name=CENPF {ECO:0000313|Ensembl:ENSSBOP00000015785};
OS   Saimiri boliviensis boliviensis (Bolivian squirrel monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC   Saimiriinae; Saimiri.
OX   NCBI_TaxID=39432 {ECO:0000313|Ensembl:ENSSBOP00000015785, ECO:0000313|Proteomes:UP000233220};
RN   [1] {ECO:0000313|Ensembl:ENSSBOP00000015785}
RP   NUCLEOTIDE SEQUENCE.
RA   Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA   MacCallum I., Young S., Walker B.J., Lindblad-Toh K.;
RT   "The Draft Genome of Saimiri boliviensis.";
RL   Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSSBOP00000015785}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2018) to UniProtKB.
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DR   RefSeq; XP_003930404.1; XM_003930355.2.
DR   Ensembl; ENSSBOT00000032588; ENSSBOP00000015785; ENSSBOG00000024619.
DR   GeneID; 101049170; -.
DR   KEGG; sbq:101049170; -.
DR   CTD; 1063; -.
DR   GeneTree; ENSGT00730000111187; -.
DR   OMA; YNAQLVQ; -.
DR   OrthoDB; 205405at2759; -.
DR   Proteomes; UP000233220; Unplaced.
DR   GO; GO:0005930; C:axoneme; IEA:Ensembl.
DR   GO; GO:0005813; C:centrosome; IEA:Ensembl.
DR   GO; GO:0036064; C:ciliary basal body; IEA:Ensembl.
DR   GO; GO:0097539; C:ciliary transition fiber; IEA:Ensembl.
DR   GO; GO:0000940; C:condensed chromosome outer kinetochore; IEA:Ensembl.
DR   GO; GO:0030496; C:midbody; IEA:Ensembl.
DR   GO; GO:0005635; C:nuclear envelope; IEA:Ensembl.
DR   GO; GO:0016363; C:nuclear matrix; IEA:Ensembl.
DR   GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR   GO; GO:0045120; C:pronucleus; IEA:Ensembl.
DR   GO; GO:0000922; C:spindle pole; IEA:Ensembl.
DR   GO; GO:0070840; F:dynein complex binding; IEA:Ensembl.
DR   GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR   GO; GO:0008022; F:protein C-terminus binding; IEA:Ensembl.
DR   GO; GO:0042803; F:protein homodimerization activity; IEA:Ensembl.
DR   GO; GO:0008134; F:transcription factor binding; IEA:Ensembl.
DR   GO; GO:0001822; P:kidney development; IEA:Ensembl.
DR   GO; GO:0051310; P:metaphase plate congression; IEA:Ensembl.
DR   GO; GO:0000278; P:mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0015031; P:protein transport; IEA:Ensembl.
DR   GO; GO:0010389; P:regulation of G2/M transition of mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0016202; P:regulation of striated muscle tissue development; IEA:Ensembl.
DR   GO; GO:0021591; P:ventricular system development; IEA:Ensembl.
DR   InterPro; IPR043513; Cenp-F.
DR   InterPro; IPR018302; CenpF/LEK1_Rb-prot-bd.
DR   InterPro; IPR019513; Centromere_CenpF_leu-rich_rpt.
DR   InterPro; IPR018463; Centromere_CenpF_N.
DR   PANTHER; PTHR18874; PTHR18874; 2.
DR   Pfam; PF10490; CENP-F_C_Rb_bdg; 1.
DR   Pfam; PF10473; CENP-F_leu_zip; 2.
DR   Pfam; PF10481; CENP-F_N; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233220}.
FT   DOMAIN          1..307
FT                   /note="CENP-F_N"
FT                   /evidence="ECO:0000259|Pfam:PF10481"
FT   DOMAIN          2132..2271
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   DOMAIN          2314..2453
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   DOMAIN          2970..3014
FT                   /note="CENP-F_C_Rb_bdg"
FT                   /evidence="ECO:0000259|Pfam:PF10490"
FT   REGION          125..161
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          192..261
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1661..1693
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1719..1741
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          2892..2961
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          2988..3115
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          164..191
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          280..384
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          386..413
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          418..466
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          477..497
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          523..615
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          623..720
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          832..873
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          899..989
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1029..1056
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1082..1120
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1132..1159
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1196..1244
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1293..1313
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1397..1417
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1549..1612
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1624..1646
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1792..1861
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1899..1968
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2003..2079
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2108..2135
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2143..2198
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2206..2279
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2297..2317
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2325..2359
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2367..2468
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2476..2555
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2563..2604
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2619..2685
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2690..2717
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2719..2739
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2754..2830
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2837..2864
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2872..2892
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        130..161
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1665..1693
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2917..2956
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        3000..3014
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        3030..3077
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   3115 AA;  357659 MW;  3C4251D8423EFC7C CRC64;
     MSWALEEWKE GLPTRALQKI QELEGQLDKL KKEKQQRQFQ LDSLEAALQK QKQKVENEKT
     EGTNLKRENQ RLIEICESLE KTKQKISHEL QVKESQVNFQ EGQLNSGKKQ IEKLEQELKR
     CKSELERSQR AAQSADGSLN PCNTPQQIST TPLTPSQYYS GSKYEDLKEK YNKEVEERKR
     LEAEVKAFQA KKANQTLPQT SMNHRDIARH QASSSVFSWQ QDKTPSRLSS SSQKTPIRRD
     TSASYFSGEQ EMTPSQSTLQ IGKRDANSSF FDNSNSPHLL DQLKVQNQEL RSKINELELR
     LQGQEKEMKS QVNKFQELQL QLEKAKVELI EKEKVLNKCR DELVRTTAQY DQASTKCTAL
     EQKLKKLTED LSCQRQNAES ARCSLEQKIK EKEKEFQEEL SRQQRSFQTL DQESIQMKAK
     LTQELQQAKN MHNVLQAELD KVTSVKQQLE KNVEEFKQKL CRAEQAFQAS EVKESELRRS
     TEEMKKENSL LKSQSEQTAR EVCHLEAELK KVKQCLNQSQ NFAEEMKVKN TSQETMLRDL
     QEKINQQENC LTLEKLKLAV ADLEKQRDCS QDLLKKREHH IEQLNDKLNK TEKESKALLS
     ALELKKKEYE ELKEEKTLFS CWKSENEKLL TQMESEKESL QSKINHLETC LKTQQIKSHE
     YNERVRTLEM ERENLSVEIR NLHNVIDSKS VEVETQKQAY EELQQKAEFS DQKHQKEIEN
     MCLKTFQLTG QVEDLEHKLQ LLSNEIMDKD RCYQDLHTEY ESLRDLLKSK DASLVTNEVH
     QRSLLAFDQL LAMHNSFANI IGEQGSMPSE RSECHLDANQ SPKNSAILQN RVDSLEFSLE
     SQKQMNSDLQ KQCEELVQIK GEIEENLMRA EQMHQSFVAE TSQRINKLQE DTSAHQNVVA
     ETLSALENKE KELQLLNGKL ETEQAEIQEL KKSNHLLEDS LKELQLLSET LSMEKKEMSS
     IISLNKREIE ELTQENGSLK EINASLNQEK MNLIQKSESF ANCINEREKS ISELSDQYNQ
     EKLILLQRCE ETGNAYEDLS QKYKAAQEKN FKLESLLNEC TTLCEHRKND LEQLKEAFAK
     EHQEFLTKLA FAEERNQNLI LELETVQQDL RSEMTDIQNN SKNEADGLKP EIMTLKEEQN
     KMQKEVNDLL QENEQLMKLM KTEHECQNLA LEPIRNSMKE RESERNQCNF KLQMNLEVKE
     ISLDSYNAQL VQLEAMLRNM ELKLKESEKE KECLQNELQT IRGKLETRNL QDMQSQEISG
     LKDCEIDAEE KHISVLRELS TTQNDNGHLQ CSLETAVNKL NELEKMCEKL QTDKCELVSE
     LNESRSGCIT ATRKMAEEVG KLVNEVKILN DDSGLLHGEL MEGIPGGEFG EQSNEQHPVS
     LATLDDSNFC EHLALSNKEV QMHFAELQEK FSSLQSEHKI LHDQHCQMSS KMLELQTYVD
     SLKAENLVLS TNLRNFQGDL VKEMQPGLKE GLVPSLSSSC LPVSPSLSSL GDCSFYKALL
     EQTGEMSLLN NLEGNVSANQ SSVDEVFCNS LEEENLTKKE IPLAPMKSVE ELESLCQVYQ
     QSLEKLEEKM ESQEIMKNKE IQELEQLLSS ERQELDCLRK RYLSENEQWQ QKLTSVTLEM
     ESKLAAEKKQ TEQLSLELEV ARLQLQGLDL SSRSLLGIDT EDAIQGRNES GDIKESKEHT
     SETTEGTPKH DAHHMCDKDV QQDLSLDIEK ITETGAVKLT GECSGEQSPD TSYETPREDK
     TQGYSECISE LSFSGTNALV PVGFPGNQEN TQNLQLQVKE ISNENLRLLH VIEDRDRKVE
     SLLNEMNELD SKLHLQEVQL MTKIEACIEL EKIVEELKKE NTDLSEKLES ISCDNQELLQ
     RVETSEGLNS NLEMCADKSS HEDIEDNAAK VNYSWKERFL DVENELSRIR SEKARIEHQA
     LSLEAALERV QIEKLCLEKD NENKQKVIVC LEEDLSVVTR ERDQLRGELD STSKKTLKLD
     QLSEKMEKTQ ELESHQSECL RCLQVAEAEV KEKTELLQTL SSDVSELLKE KTHLQEKLQS
     LEKDSQALSL AKCELENQIA QLNEEKELLV KESESLQARL SESDYEKLNV SKALEAALVE
     KGEFALRLSS TQEEVHQLRR GIEKLRVRIE ADEKKQLHVA EKLKEREREN DSLKDKVENL
     ERELQMSEEN QELVILDAEN SKAEVETLKT QLEETARSLK VFELDHVMLR SEKENLAKQL
     QEKQGQVSEL DKLLSSFKSL LEEKEQAEIQ VKEESKTAAE MLQNQLKELN DAVAALCGDQ
     ETVKATEQSL DSPVEEVHQL RNSIEKLRVH LEADEKKQLC VLEQLKESEH EADLLKGRME
     NLERELELSR KNQEHAVLEA ENSKGEVDTL KAKIEGMTQS LRDLELDLVT IRSEKENLTN
     ALQKEQERIS ELEIINSSFE NILQEKEQEK VQMKEKSNTA VEMLQTQLRE LNERVAALHN
     DQETCKAKEQ NLSSQVDCLE LEKAQLLQGL EEAKNNYIVL QSSVNGLIQE VEDGKQKLEK
     KDEEISRLKN QIQDQEQLIS KLSEVEGEHQ LLKKQNLELV NLTVELEQKI QVLQSKNASL
     QDTLEVLQSS YKSLENELEL TKMDKMSFVE KVNTMTAKET ELQREMHEMA QKTAELQEEL
     NGEKNRLTGE LQLLLEEIKS SKDQLKELTL ENSELKKSLD CMHEDQVEKE GKVREEIAEY
     QLRLHEAEKK HQAVLLDTNK QYEIEIQTYQ EKLSSKEECL TSQKLEMDLL KSSKEELSNS
     LKATTQVLEE LKKTKMDHLK YVNQLKKENE HAQGKIKLLM KSCKQLEEEK ETLQKELSQL
     EAAQERQKTG AILDAKVDEF MTEIKELKET LEEKTKEADE YLDKYCSLLI RHEKLEKAKE
     MLETQVAHLC SQQSKQDFRG SPLLDGAVPE PSPMPSATEK RLSSGPNKAS GKRQRSSGIW
     ENGRGPTPST PETFSKKSKK AVMRGIHPAK DTEDTEFEPE GLPEVVKKGF ADIPTGKTSP
     YILRRTTMAT RTSPRLAAQK LALSPLSLGK ENLAESSKPT AGGSRSQKVK VAQQSPVDSG
     TVLQEPTTKS LLVNNLPERS PADSPKEGLR AKRGRLTPSP KAGVEPKGSE NCKVQ
//
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