ID   A0A2K6TAS6_SAIBB        Unreviewed;       211 AA.
AC   A0A2K6TAS6;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   RecName: Full=Apolipoprotein D {ECO:0000256|ARBA:ARBA00019890, ECO:0000256|PIRNR:PIRNR036893};
DE            Short=Apo-D {ECO:0000256|PIRNR:PIRNR036893};
GN   Name=APOD {ECO:0000313|Ensembl:ENSSBOP00000016751.1};
OS   Saimiri boliviensis boliviensis (Bolivian squirrel monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC   Saimiriinae; Saimiri.
OX   NCBI_TaxID=39432 {ECO:0000313|Ensembl:ENSSBOP00000016751.1, ECO:0000313|Proteomes:UP000233220};
RN   [1] {ECO:0000313|Ensembl:ENSSBOP00000016751.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBUNIT: Homodimer. {ECO:0000256|PIRNR:PIRNR036893}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC   -!- SIMILARITY: Belongs to the calycin superfamily. Lipocalin family.
CC       {ECO:0000256|ARBA:ARBA00006889, ECO:0000256|PIRNR:PIRNR036893,
CC       ECO:0000256|RuleBase:RU003695}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; A0A2K6TAS6; -.
DR   STRING; 39432.ENSSBOP00000016751; -.
DR   Ensembl; ENSSBOT00000033557.1; ENSSBOP00000016751.1; ENSSBOG00000025056.1.
DR   GeneTree; ENSGT00510000046981; -.
DR   Proteomes; UP000233220; Unplaced.
DR   GO; GO:0005615; C:extracellular space; IEA:Ensembl.
DR   GO; GO:0048471; C:perinuclear region of cytoplasm; IEA:Ensembl.
DR   GO; GO:0015485; F:cholesterol binding; IEA:Ensembl.
DR   GO; GO:0007420; P:brain development; IEA:InterPro.
DR   GO; GO:0006006; P:glucose metabolic process; IEA:Ensembl.
DR   GO; GO:0006629; P:lipid metabolic process; IEA:Ensembl.
DR   GO; GO:0006869; P:lipid transport; IEA:InterPro.
DR   GO; GO:1900016; P:negative regulation of cytokine production involved in inflammatory response; IEA:Ensembl.
DR   GO; GO:0051895; P:negative regulation of focal adhesion assembly; IEA:Ensembl.
DR   GO; GO:0060588; P:negative regulation of lipoprotein lipid oxidation; IEA:Ensembl.
DR   GO; GO:0071638; P:negative regulation of monocyte chemotactic protein-1 production; IEA:Ensembl.
DR   GO; GO:0010642; P:negative regulation of platelet-derived growth factor receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0042308; P:negative regulation of protein import into nucleus; IEA:Ensembl.
DR   GO; GO:0048662; P:negative regulation of smooth muscle cell proliferation; IEA:Ensembl.
DR   GO; GO:2000098; P:negative regulation of smooth muscle cell-matrix adhesion; IEA:Ensembl.
DR   GO; GO:2000405; P:negative regulation of T cell migration; IEA:Ensembl.
DR   GO; GO:0000302; P:response to reactive oxygen species; IEA:Ensembl.
DR   GO; GO:0042246; P:tissue regeneration; IEA:InterPro.
DR   CDD; cd19437; lipocalin_apoD-like; 1.
DR   Gene3D; 2.40.128.20; -; 1.
DR   InterPro; IPR026222; ApoD_vertbrte.
DR   InterPro; IPR002969; ApolipopD.
DR   InterPro; IPR012674; Calycin.
DR   InterPro; IPR022271; Lipocalin_ApoD.
DR   InterPro; IPR022272; Lipocalin_CS.
DR   InterPro; IPR000566; Lipocln_cytosolic_FA-bd_dom.
DR   PANTHER; PTHR10612; APOLIPOPROTEIN D; 1.
DR   PANTHER; PTHR10612:SF34; APOLIPOPROTEIN D; 1.
DR   Pfam; PF00061; Lipocalin; 1.
DR   PIRSF; PIRSF036893; Lipocalin_ApoD; 1.
DR   PRINTS; PR02058; APODVERTBRTE.
DR   PRINTS; PR01219; APOLIPOPROTD.
DR   PRINTS; PR00179; LIPOCALIN.
DR   SUPFAM; SSF50814; Lipocalins; 1.
DR   PROSITE; PS00213; LIPOCALIN; 1.
PE   3: Inferred from homology;
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Lipid-binding {ECO:0000256|ARBA:ARBA00023121};
KW   Pyrrolidone carboxylic acid {ECO:0000256|ARBA:ARBA00023283};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233220};
KW   Secreted {ECO:0000256|ARBA:ARBA00022525};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW   Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   SIGNAL          1..44
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           45..211
FT                   /note="Apolipoprotein D"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5014377028"
FT   DOMAIN          68..207
FT                   /note="Lipocalin/cytosolic fatty-acid binding"
FT                   /evidence="ECO:0000259|Pfam:PF00061"
SQ   SEQUENCE   211 AA;  23935 MW;  7E507DB5417510ED CRC64;
     GILLHDCVAL ESSERSLLQP PSPKMMMPLL LLFALAGLFG AAEGQTFHLG KCPMPPVQEN
     FDVNKYLGRW YEIEKIPTTF EKGRCIQANY SLMDNGNIKV LNRELRYDGT VNQIEGEATQ
     VNLTEPAKLA VKFFWLMPSA PYWVLATDYE NYALVYSCTD FIQLFHVDFA WILGRNSYLP
     PETVDSLKNI LTSNNIPVDK MTVTDQMNCP E
//