ID A0A2K6TCI6_SAIBB Unreviewed; 487 AA.
AC A0A2K6TCI6;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Calcium voltage-gated channel auxiliary subunit beta 4 {ECO:0000313|Ensembl:ENSSBOP00000017347.1};
GN Name=CACNB4 {ECO:0000313|Ensembl:ENSSBOP00000017347.1};
OS Saimiri boliviensis boliviensis (Bolivian squirrel monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Saimiriinae; Saimiri.
OX NCBI_TaxID=39432 {ECO:0000313|Ensembl:ENSSBOP00000017347.1, ECO:0000313|Proteomes:UP000233220};
RN [1] {ECO:0000313|Ensembl:ENSSBOP00000017347.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the calcium channel beta subunit family.
CC {ECO:0000256|ARBA:ARBA00010836}.
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DR AlphaFoldDB; A0A2K6TCI6; -.
DR Ensembl; ENSSBOT00000034159.1; ENSSBOP00000017347.1; ENSSBOG00000025206.1.
DR GeneTree; ENSGT00950000182837; -.
DR Proteomes; UP000233220; Unplaced.
DR GO; GO:0005891; C:voltage-gated calcium channel complex; IEA:InterPro.
DR GO; GO:0005245; F:voltage-gated calcium channel activity; IEA:InterPro.
DR CDD; cd12043; SH3_CACNB4; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR046937; CAB1-4_N_A-dom.
DR InterPro; IPR008145; GK/Ca_channel_bsu.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR000584; VDCC_L_bsu.
DR PANTHER; PTHR11824; VOLTAGE-DEPENDENT CALCIUM CHANNEL BETA SUBUNIT; 1.
DR PANTHER; PTHR11824:SF7; VOLTAGE-DEPENDENT L-TYPE CALCIUM CHANNEL SUBUNIT BETA-4; 1.
DR Pfam; PF00625; Guanylate_kin; 1.
DR Pfam; PF12052; VGCC_beta4Aa_N; 1.
DR PRINTS; PR01626; LCACHANNELB.
DR SMART; SM00072; GuKc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50002; SH3; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000233220};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 62..131
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 136..156
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 392..487
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 392..422
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 423..468
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 487 AA; 54864 MW; 143A8E5188CAE037 CRC64;
LQKSHRTTHH RKLFCFPFQG SADSYTSRPS DSDVSLEEDR EAIRQEREQQ AAIQLERAKS
KPVAFAVKTN VSYCGALDED VPVPSTAISF DAKDFLHIKE KYNNDWWIGR LVKEGCEIGF
IPSPLRLENI RIQQEQKRGR FHGGKSSGNS SSSLGEMVSG TFRATPTSTG ESLTEHIPPY
DVVPSMRPVV LVGPSLKGYE VTDMMQKALF DFLKHRFDGR ISITRVTADI SLAKRSVLNN
PSKRAIIERS NTRSSLAEVQ SEIERIFELA RSLQLVVLDA DTINHPAQLI KTSLAPIIVH
VKVSSPKVLQ RLIKSRGKSQ SKHLNVQLVA ADKLAQCPPE MFDVILDENQ LEDACEHLGE
YLEAYWRATH TTGSTPMTPL LGRNLGSTAL SPYPTAISGL QSQRMRHSNH STENSPIERR
SLMTSDENYH NERARKSRNR LSSSSQHSRD HYPLVEEDYP DSYPDTYKPH RNRGSPGGYS
HDSRHRL
//
