ID A0A2K6TE89_SAIBB Unreviewed; 199 AA.
AC A0A2K6TE89;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE SubName: Full=Interleukin 11 {ECO:0000313|Ensembl:ENSSBOP00000017962.1};
GN Name=IL11 {ECO:0000313|Ensembl:ENSSBOP00000017962.1};
OS Saimiri boliviensis boliviensis (Bolivian squirrel monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Saimiriinae; Saimiri.
OX NCBI_TaxID=39432 {ECO:0000313|Ensembl:ENSSBOP00000017962.1, ECO:0000313|Proteomes:UP000233220};
RN [1] {ECO:0000313|Ensembl:ENSSBOP00000017962.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR RefSeq; XP_003944728.1; XM_003944679.2.
DR AlphaFoldDB; A0A2K6TE89; -.
DR STRING; 39432.ENSSBOP00000017962; -.
DR Ensembl; ENSSBOT00000034778.1; ENSSBOP00000017962.1; ENSSBOG00000025620.1.
DR GeneID; 101048956; -.
DR KEGG; sbq:101048956; -.
DR CTD; 3589; -.
DR GeneTree; ENSGT00390000007165; -.
DR OMA; WAYRAFI; -.
DR OrthoDB; 4636833at2759; -.
DR Proteomes; UP000233220; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:Ensembl.
DR GO; GO:0005615; C:extracellular space; IEA:Ensembl.
DR GO; GO:0005125; F:cytokine activity; IEA:Ensembl.
DR GO; GO:0008083; F:growth factor activity; IEA:Ensembl.
DR GO; GO:0005142; F:interleukin-11 receptor binding; IEA:Ensembl.
DR GO; GO:0008283; P:cell population proliferation; IEA:Ensembl.
DR GO; GO:0038154; P:interleukin-11-mediated signaling pathway; IEA:Ensembl.
DR GO; GO:0046888; P:negative regulation of hormone secretion; IEA:Ensembl.
DR GO; GO:0008284; P:positive regulation of cell population proliferation; IEA:Ensembl.
DR GO; GO:0043410; P:positive regulation of MAPK cascade; IEA:Ensembl.
DR GO; GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IEA:Ensembl.
DR GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IEA:Ensembl.
DR GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IEA:Ensembl.
DR Gene3D; 1.20.1250.10; -; 1.
DR InterPro; IPR009079; 4_helix_cytokine-like_core.
DR InterPro; IPR020438; IL-11.
DR InterPro; IPR020412; IL-11_mml.
DR PANTHER; PTHR16922; INTERLEUKIN 11; 1.
DR PANTHER; PTHR16922:SF0; INTERLEUKIN-11; 1.
DR Pfam; PF07400; IL11; 1.
DR PRINTS; PR01943; INTLKN11MAML.
DR PRINTS; PR01927; INTRLEUKIN11.
DR SUPFAM; SSF47266; 4-helical cytokines; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000233220};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..199
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014402145"
SQ SEQUENCE 199 AA; 21446 MW; 19614328A8BC0761 CRC64;
MNWVCHLVLV VLSLWPDTAV APGPPPGPPR ASPDPRAELD STVLLTRSLL ADTRQLAAQL
RDKFPADGDH NLDSLPTLAM SAGALGALQL PGVLTRLRAD LLSYLRHVQW LRRAGGSSLK
TLEPELGTLQ ARLDRLLRRL QLLMSHLALP QPPPDPPAPP LAPPSSAWGG IRAAHAILGG
LHLTLDWAVR GLLLLKTRL
//
