ID A0A2K6TEN5_SAIBB Unreviewed; 541 AA.
AC A0A2K6TEN5;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Tripartite motif containing 46 {ECO:0000313|Ensembl:ENSSBOP00000018108.1};
GN Name=TRIM46 {ECO:0000313|Ensembl:ENSSBOP00000018108.1};
OS Saimiri boliviensis boliviensis (Bolivian squirrel monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Saimiriinae; Saimiri.
OX NCBI_TaxID=39432 {ECO:0000313|Ensembl:ENSSBOP00000018108.1, ECO:0000313|Proteomes:UP000233220};
RN [1] {ECO:0000313|Ensembl:ENSSBOP00000018108.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}.
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DR AlphaFoldDB; A0A2K6TEN5; -.
DR Ensembl; ENSSBOT00000034923.1; ENSSBOP00000018108.1; ENSSBOG00000025545.1.
DR GeneTree; ENSGT00940000158021; -.
DR OMA; XIARATE; -.
DR Proteomes; UP000233220; Unplaced.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd19849; Bbox1_TRIM46_C-I; 1.
DR CDD; cd19786; Bbox2_TRIM46_C-I; 1.
DR CDD; cd00063; FN3; 1.
DR CDD; cd16757; RING-HC_TRIM46_C-I; 1.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 4.10.830.40; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR017903; COS_domain.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR040859; Midline-1_COS.
DR InterPro; IPR027370; Znf-RING_euk.
DR InterPro; IPR000315; Znf_B-box.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR24099; E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED; 1.
DR PANTHER; PTHR24099:SF20; TRIPARTITE MOTIF-CONTAINING PROTEIN 46; 1.
DR Pfam; PF18568; COS; 1.
DR Pfam; PF00643; zf-B_box; 1.
DR Pfam; PF13445; zf-RING_UBOX; 1.
DR SMART; SM00336; BBOX; 1.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF57845; B-box zinc-binding domain; 1.
DR SUPFAM; SSF49265; Fibronectin type III; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS51262; COS; 1.
DR PROSITE; PS50853; FN3; 1.
DR PROSITE; PS50119; ZF_BBOX; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00023212};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000233220};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00024}.
FT DOMAIN 209..250
FT /note="B box-type"
FT /evidence="ECO:0000259|PROSITE:PS50119"
FT DOMAIN 357..414
FT /note="COS"
FT /evidence="ECO:0000259|PROSITE:PS51262"
FT DOMAIN 416..515
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 54..86
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 62..79
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 541 AA; 60703 MW; A4BBFF8A54A62C56 CRC64;
MAAKRGTKTS MKNMEKELLC PVCQEMYKQP LVLPCTHNVC QACAREVLGQ QGYIGHGGDP
SSEPTSPAST PSTRSPRLSR RTLPKPDRLD RLLKSGFGTY PGRKRGALHP QVIMFPCPAC
QGDVELGERG LAGLFRNLTL ERVVERYRQS VSVGGAILCQ LCKPPPLEAT KGCTECRATF
CNECFKLFHP WGTQKAQHEP TLPTLSFRPK GLMCPDHKEE VTHYCKTCQR LVCQLCRVRR
THSGHKITPV LSAYQALKDK LTKSLTYILG NQDTVQTQIC ELEEAVRHTE VSGQQAKEEV
SQLVRGLGAV LEEKRASLLQ AIEECQQERL ARLSAQIQEH RSLLDGSGLV GYAQEVLKET
DQPCFVQAAK QLHNRIARAT EALQTFRPAA SSSFRHCQLD VGREMKLLTE LNFLRAPEAP
VIDTQRTFAY DQIFLCWRLP PHSPPAWHYT VEFRRTDVPA QPGPARWQRR EEVRGTSALL
ENPDTGSVYV LRVRGWNKAG YGEYSEDVHL HTPPAPGTTR TAGTTAVLRM PPWRRRRPSL
S
//
