ID A0A2K6TMJ0_SAIBB Unreviewed; 691 AA.
AC A0A2K6TMJ0;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=Solute carrier organic anion transporter family member {ECO:0000256|RuleBase:RU362056};
GN Name=SLCO1B1 {ECO:0000313|Ensembl:ENSSBOP00000020881.1};
OS Saimiri boliviensis boliviensis (Bolivian squirrel monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Saimiriinae; Saimiri.
OX NCBI_TaxID=39432 {ECO:0000313|Ensembl:ENSSBOP00000020881.1, ECO:0000313|Proteomes:UP000233220};
RN [1] {ECO:0000313|Ensembl:ENSSBOP00000020881.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU362056};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU362056}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the organo anion transporter (TC 2.A.60) family.
CC {ECO:0000256|ARBA:ARBA00009657, ECO:0000256|RuleBase:RU362056}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU362056}.
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DR RefSeq; XP_003926604.1; XM_003926555.2.
DR AlphaFoldDB; A0A2K6TMJ0; -.
DR STRING; 39432.ENSSBOP00000020881; -.
DR Ensembl; ENSSBOT00000037715.1; ENSSBOP00000020881.1; ENSSBOG00000027016.1.
DR GeneID; 101037794; -.
DR KEGG; sbq:101037794; -.
DR GeneTree; ENSGT01080000257336; -.
DR OMA; KKTRYCN; -.
DR OrthoDB; 2874223at2759; -.
DR Proteomes; UP000233220; Unplaced.
DR GO; GO:0009925; C:basal plasma membrane; IEA:Ensembl.
DR GO; GO:0008514; F:organic anion transmembrane transporter activity; IEA:Ensembl.
DR GO; GO:0015132; F:prostaglandin transmembrane transporter activity; IEA:Ensembl.
DR GO; GO:0006811; P:monoatomic ion transport; IEA:UniProtKB-KW.
DR Gene3D; 3.30.60.30; -; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR002350; Kazal_dom.
DR InterPro; IPR036058; Kazal_dom_sf.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR004156; OATP.
DR NCBIfam; TIGR00805; oat; 1.
DR PANTHER; PTHR11388; ORGANIC ANION TRANSPORTER; 1.
DR PANTHER; PTHR11388:SF82; SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 1B1; 1.
DR Pfam; PF07648; Kazal_2; 1.
DR Pfam; PF03137; OATP; 1.
DR SUPFAM; SSF100895; Kazal-type serine protease inhibitors; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS51465; KAZAL_2; 1.
DR PROSITE; PS50850; MFS; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Ion transport {ECO:0000256|RuleBase:RU362056};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362056};
KW Reference proteome {ECO:0000313|Proteomes:UP000233220};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362056};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362056}; Transport {ECO:0000256|RuleBase:RU362056}.
FT TRANSMEM 29..48
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT TRANSMEM 68..89
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT TRANSMEM 96..117
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT TRANSMEM 207..230
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT TRANSMEM 257..279
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT TRANSMEM 337..363
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT TRANSMEM 375..397
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT TRANSMEM 409..428
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT TRANSMEM 534..560
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT TRANSMEM 572..595
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT TRANSMEM 615..646
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT DOMAIN 30..647
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
FT DOMAIN 453..508
FT /note="Kazal-like"
FT /evidence="ECO:0000259|PROSITE:PS51465"
SQ SEQUENCE 691 AA; 76308 MW; 121430DAED9D6B0C CRC64;
MDKNQHLIKT AEAQSSENKK TRYCNGFKMF LAALSLSFIA RTLGAVVMKS NTIHIERRFD
ISSSLVGLID GSFEIGNLFV IVFVSYFGSK LHRPKLIGIG CFIMGLGGVL TALPHFFMGY
YRYSKETNIN SSENLTSTLA TCLIKPILSL NRTSPEIVGK GCLKESGSYM WIFVLMGNML
RGIGETPIAP LGISYIDDFA TEGHSSLYLG MLNAIAVIGP VIGFAMGSVF SKMYVDIGYV
DLSRIRITPN DSRWVGAWWL GFLVSGLLSI ISSIPFFFLP QTPNKPQKER KASLSLHVLK
TNDENNQTAN LTNQGKNITK NVNGFLQSFK SILTNPFYVI FVLLTLLQVS SYIGSFTFIF
KYVEQQYGQS ASKANISLGM IILPVFATGM FLGGYIIKKF KLNPVGIAKF SFFTAVMSFF
FHLLYFSMLC ENKSVAGLTM TYDGNSSMTS HIDGPVSYCN SDCNCDERQW EPVCGSNGIT
YISPCLAGCK SSSGNEKPIV FYNCSCLEVT GIQNRNYSAH LGECPREDAC TRKFYPFVAI
QVFNLFFSAL GGTSFIMLIV KIVQPELKSL ALGFQSMVIR ALGGILAPIY FGALIDRTCM
KWSTSSCGTH GSCRIYNSTL FAIVFLGLSS ILRVSSFVLY IVLIYAMKKK YEEKDINASE
NASVMDEANL ESLNNNQHLV PSAGADSKTH Y
//
