ID A0A2K6TMU1_SAIBB Unreviewed; 1591 AA.
AC A0A2K6TMU1;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Eukaryotic translation initiation factor 4 gamma 3 {ECO:0000313|Ensembl:ENSSBOP00000020971.1};
GN Name=EIF4G3 {ECO:0000313|Ensembl:ENSSBOP00000020971.1};
OS Saimiri boliviensis boliviensis (Bolivian squirrel monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Saimiriinae; Saimiri.
OX NCBI_TaxID=39432 {ECO:0000313|Ensembl:ENSSBOP00000020971.1, ECO:0000313|Proteomes:UP000233220};
RN [1] {ECO:0000313|Ensembl:ENSSBOP00000020971.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the eukaryotic initiation factor 4G family.
CC {ECO:0000256|ARBA:ARBA00005775}.
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DR Ensembl; ENSSBOT00000037805.1; ENSSBOP00000020971.1; ENSSBOG00000026901.1.
DR GeneTree; ENSGT00940000156454; -.
DR Proteomes; UP000233220; Unplaced.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR CDD; cd11559; W2_eIF4G1_like; 1.
DR Gene3D; 1.25.40.180; -; 3.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR045208; IF4G.
DR InterPro; IPR003891; Initiation_fac_eIF4g_MI.
DR InterPro; IPR003890; MIF4G-like_typ-3.
DR InterPro; IPR003307; W2_domain.
DR PANTHER; PTHR23253; EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA; 1.
DR PANTHER; PTHR23253:SF23; EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA 3; 1.
DR Pfam; PF02847; MA3; 1.
DR Pfam; PF02854; MIF4G; 1.
DR Pfam; PF02020; W2; 1.
DR SMART; SM00515; eIF5C; 1.
DR SMART; SM00544; MA3; 1.
DR SMART; SM00543; MIF4G; 1.
DR SUPFAM; SSF48371; ARM repeat; 3.
DR PROSITE; PS51366; MI; 1.
DR PROSITE; PS51363; W2; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000233220}.
FT DOMAIN 1227..1349
FT /note="MI"
FT /evidence="ECO:0000259|PROSITE:PS51366"
FT DOMAIN 1422..1591
FT /note="W2"
FT /evidence="ECO:0000259|PROSITE:PS51363"
FT REGION 1..43
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 135..197
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 214..238
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 311..338
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 478..501
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 573..626
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 694..717
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 735..755
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 866..886
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1023..1048
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1078..1226
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 23..43
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 143..159
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 176..194
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 314..332
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 595..609
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1092..1133
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1194..1208
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1591 AA; 177110 MW; 1B8582D2940BBF3E CRC64;
MNSQPQTRSP GGFRPIQFFQ RPQIQPPRAT IPNSSPSIRP GAQTPTAVYQ ANQHIMMVNH
LPMPYPVPQG PQYCIPQYRH SGPPYVGPPQ QYPVQPPGPG PFYPGPGPGD FPNAYGTPFY
PSQPVYQSAP IIVPTQQQPP PAKREKKTIR IRDPNQGGKD ITEEIMSGGG SRNPTPPIGR
PTPTPTPPQL PSQVPEHSPV VYGTVESAHL AASTPVTAAS DQKQEEKPKP DPVLKSPSPV
LRLVLSGEKK EQEGQTSEAA AIVSIPELPL PPLPTTVSSI ARSTIASSAS SAVSSQPIFT
TAIDDRCELS SSREDTVPIP SLTSCTETSD PLPTGENDDD ICKKPCSVAP NDIPLISSTN
LINEINGVNE KLPATESMAE VAKQEVLPLT LEFEILENPP EEMKLERIPA PITPSTIPSF
PSTPPTPPAS PPPIPVIVPA ATTTVSSPSA AITVQRVLEE DESIRTCLSE DAKEIQNKTE
VEADGQTEDI LDSQNLNSRK SPVPAQIAIT VPKTWKKPKD RTRTTEEMLE AELELKAEEE
LSVDKVLESE QDKMSQGFHP ERDPSDLKKV KAVEENGEEA EPVRNGAESV SEGEGIDANS
GSTDSSGDGV TFPFKPESWK PTDTEGKKQY DREFLLDFQF MPACIQKPEG LPPISDVVLD
KINQPKLPMR TLDPRILPRG PDFTPAFADF GRQAPGGRGV PLLNVGPRRS QPGQRREPRK
IITVSVKEDV HLKKAENAWK PSQKRDSQAD DPENIKTQEL FRKVRSILNK LTPQMFNQLM
KQVSGLTVDT EERLKGVIDL VFEKAIDEPS FSVAYANMCR CLVTLKVPMA DKPGNTVNFR
KLLLNRCQKE FEKDKADDDV FEKKQKELEA ASAPEERTRL HDELEEAKDK ARRRSIGNIK
FIGELFKLKM LTEAIMHDCV VKLLKNHDEE SLECLCRLLT TIGKDLDFEK AKPRMDQYFN
QMEKIVKERK TSSRIRFMLQ DVIDLRLCNW VSRRADQGPK TIEQIHKEAK IEEQEEQRKV
QQLMTKEKRR PGVQRVDEGG WNTVQGAKNS RVLDPSKFLK ITKPTIDEKI QLVPKAQLGS
WGKGSSGGAK ASETDALRSS ASSLNRFSAL QPPAPSGSTP STPVEFDSRR TLTSRGSMGR
EKNDKPLPSA TARPNTFMRG GSSKDLLDNQ SQEEQRREML ETVKQLTGGV DVERNSTEAE
RNKTRESAKP EISTVSAPDK PALSEEEMER KSKSIIDEFL HINDFKEAMQ CVEELNAQGL
LHVFVRVGVE STLERSQITR DHMGQLLYQL VQSEKLSKQD FFKGFSETLE LADDMAIDIP
HIWLYLAELV TPMLKEGGIS MRELTIEFSK PLLPVGRAGV LLSEILHLLC KQMSHKKVGA
LWREADLSWK DFLPEGEDVH NFLLEQNLDF IESDSPSSSE TLSKKELSAE ELNKRLEKLI
IEDKANDEQI FDWVEANLDE SQMSSPTFLR ALMTAVCKAA IIADCSTFRV DTAVIKQRVP
ILLKYLDSDT EKELQALYAL QASVVKLDQP ANLLRMFFDC LYDEEVISED AFYKWESSKD
PAEQNGKGVA LKSVTAFFTW LREAEEESED N
//
