ID A0A2K6TMZ0_SAIBB Unreviewed; 1625 AA.
AC A0A2K6TMZ0;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Eukaryotic translation initiation factor 4 gamma 3 {ECO:0000313|Ensembl:ENSSBOP00000021023.1};
GN Name=EIF4G3 {ECO:0000313|Ensembl:ENSSBOP00000021023.1};
OS Saimiri boliviensis boliviensis (Bolivian squirrel monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Saimiriinae; Saimiri.
OX NCBI_TaxID=39432 {ECO:0000313|Ensembl:ENSSBOP00000021023.1, ECO:0000313|Proteomes:UP000233220};
RN [1] {ECO:0000313|Ensembl:ENSSBOP00000021023.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the eukaryotic initiation factor 4G family.
CC {ECO:0000256|ARBA:ARBA00005775}.
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DR Ensembl; ENSSBOT00000037857.1; ENSSBOP00000021023.1; ENSSBOG00000026901.1.
DR GeneTree; ENSGT00940000156454; -.
DR Proteomes; UP000233220; Unplaced.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR CDD; cd11559; W2_eIF4G1_like; 1.
DR Gene3D; 1.25.40.180; -; 3.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR045208; IF4G.
DR InterPro; IPR003891; Initiation_fac_eIF4g_MI.
DR InterPro; IPR003890; MIF4G-like_typ-3.
DR InterPro; IPR003307; W2_domain.
DR PANTHER; PTHR23253; EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA; 1.
DR PANTHER; PTHR23253:SF23; EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA 3; 1.
DR Pfam; PF02847; MA3; 1.
DR Pfam; PF02854; MIF4G; 1.
DR Pfam; PF02020; W2; 1.
DR SMART; SM00515; eIF5C; 1.
DR SMART; SM00544; MA3; 1.
DR SMART; SM00543; MIF4G; 1.
DR SUPFAM; SSF48371; ARM repeat; 3.
DR PROSITE; PS51366; MI; 1.
DR PROSITE; PS51363; W2; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000233220}.
FT DOMAIN 1261..1383
FT /note="MI"
FT /evidence="ECO:0000259|PROSITE:PS51366"
FT DOMAIN 1456..1625
FT /note="W2"
FT /evidence="ECO:0000259|PROSITE:PS51363"
FT REGION 20..39
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 131..193
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 211..235
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 308..335
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 475..498
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 570..623
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 767..788
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 900..920
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1057..1082
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1112..1260
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 22..39
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 139..155
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 172..190
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 311..329
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 592..606
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1126..1167
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1228..1242
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1625 AA; 180801 MW; 5A1FF179FC9224FE CRC64;
LNSQVKTCHS DFLFFQRPQI QPPRATIPNS SPSIRPGAQT PTAVYQANQH IMMVNHLPMP
YPVPQGPQYC IPQYRHSGPP YVGPPQQYPV QPPGPGPFYP GPGPGDFPNA YGTPFYPSQP
VYQSAPIIVP TQQQPPPAKR EKKTIRIRDP NQGGKDITEE IMSGGGSRNP TPPIGRPTPT
PTPPQQLPSQ VPEHSPVVYG TVESAHLAAS TPVTAASDQK QEEKPKPDPV LKSPSPVLRL
VLSGEKKEQE GQTSEAAAIV SIPELPLPPL PTTVSSIARS TIASSASSAV SSQPIFTTAI
DDRCELSSSR EDTVPIPSLT SCTETSDPLP TGENDDDICK KPCSVAPNDI PLISSTNLIN
EINGVNEKLP ATESMAEVAK QEVLPLTLEF EILENPPEEM KLERIPAPIT PSTIPSFPST
PPTPPASPPP IPVIVPAATT TVSSPSAAIT VQRVLEEDES IRTCLSEDAK EIQNKTEVEA
DGQTEDILDS QNLNSRKSPV PAQIAITVPK TWKKPKDRTR TTEEMLEAEL ELKAEEELSV
DKVLESEQDK MSQGFHPERD PSDLKKVKAV EENGEEAEPV RNGAESVSEG EGIDANSGST
DSSGDGVTFP FKPESWKPTD TEGKKQYDRE FLLDFQFMPA CIQKPEGLPP ISDVVLDKIN
QPKLPMRTLD PRILPRGPDF TPAFADFGRQ APGGRGVPIC KVQSRHGLPI LEQNKAPTCP
PLAMSHPPMK SLPLGLLNVG PRRSQPGQRR EPRKIITVSV KEDVHLKKAE NAWKPSQKRD
SQADDPENIK TQELFRKVRS ILNKLTPQMF NQLMKQVSGL TVDTEERLKG VIDLVFEKAI
DEPSFSVAYA NMCRCLVTLK VPMADKPGNT VNFRKLLLNR CQKEFEKDKA DDDVFEKKQK
ELEAASAPEE RTRLHDELEE AKDKARRRSI GNIKFIGELF KLKMLTEAIM HDCVVKLLKN
HDEESLECLC RLLTTIGKDL DFEKAKPRMD QYFNQMEKIV KERKTSSRIR FMLQDVIDLR
LCNWVSRRAD QGPKTIEQIH KEAKIEEQEE QRKVQQLMTK EKRRPGVQRV DEGGWNTVQG
AKNSRVLDPS KFLKITKPTI DEKIQLVPKA QLGSWGKGSS GGAKASETDA LRSSASSLNR
FSALQPPAPS GSTPSTPVEF DSRRTLTSRG SMGREKNDKP LPSATARPNT FMRGGSSKDL
LDNQSQEEQR REMLETVKQL TGGVDVERNS TEAERNKTRE SAKPEISTVS APDKPALSEE
EMERKSKSII DEFLHINDFK EAMQCVEELN AQGLLHVFVR VGVESTLERS QITRDHMGQL
LYQLVQSEKL SKQDFFKGFS ETLELADDMA IDIPHIWLYL AELVTPMLKE GGISMRELTI
EFSKPLLPVG RAGVLLSEIL HLLCKQMSHK KVGALWREAD LSWKDFLPEG EDVHNFLLEQ
NLDFIESDSP SSSETLSKKE LSAEELNKRL EKLIIEDKAN DEQIFDWVEA NLDESQMSSP
TFLRALMTAV CKAAIIADCS TFRVDTAVIK QRVPILLKYL DSDTEKELQA LYALQASVVK
LDQPANLLRM FFDCLYDEEV ISEDAFYKWE SSKDPAEQNG KGVALKSVTA FFTWLREAEE
ESEDN
//
