ID A0A2K6TPY8_SAIBB Unreviewed; 1400 AA.
AC A0A2K6TPY8;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=ERCC excision repair 6 like 2 {ECO:0000313|Ensembl:ENSSBOP00000021700.1};
GN Name=ERCC6L2 {ECO:0000313|Ensembl:ENSSBOP00000021700.1};
OS Saimiri boliviensis boliviensis (Bolivian squirrel monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Saimiriinae; Saimiri.
OX NCBI_TaxID=39432 {ECO:0000313|Ensembl:ENSSBOP00000021700.1, ECO:0000313|Proteomes:UP000233220};
RN [1] {ECO:0000313|Ensembl:ENSSBOP00000021700.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the SNF2/RAD54 helicase family.
CC {ECO:0000256|ARBA:ARBA00007025}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_010347070.1; XM_010348768.1.
DR Ensembl; ENSSBOT00000038536.1; ENSSBOP00000021694.1; ENSSBOG00000027390.1.
DR Ensembl; ENSSBOT00000038542.1; ENSSBOP00000021700.1; ENSSBOG00000027390.1.
DR GeneTree; ENSGT00940000163752; -.
DR OrthoDB; 5399336at2759; -.
DR Proteomes; UP000233220; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProt.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0140658; F:ATP-dependent chromatin remodeler activity; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd18005; DEXHc_ERCC6L2; 1.
DR CDD; cd18793; SF2_C_SNF; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.40.50.10810; Tandem AAA-ATPase domain; 1.
DR InterPro; IPR002464; DNA/RNA_helicase_DEAH_CS.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR029256; Heliccase-ass-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038718; SNF2-like_sf.
DR InterPro; IPR049730; SNF2/RAD54-like_C.
DR InterPro; IPR000330; SNF2_N.
DR PANTHER; PTHR45629:SF7; DNA EXCISION REPAIR PROTEIN ERCC-6-RELATED; 1.
DR PANTHER; PTHR45629; SNF2/RAD54 FAMILY MEMBER; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF00176; SNF2-rel_dom; 1.
DR Pfam; PF14773; VIGSSK; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00690; DEAH_ATP_HELICASE; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000233220}.
FT DOMAIN 1..172
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 363..513
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 568..593
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 616..636
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 766..810
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 904..943
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1200..1263
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1301..1320
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 574..593
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 776..808
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 920..940
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1200..1214
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1215..1236
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1237..1263
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1400 AA; 158735 MW; 0610A4FC8968D8C9 CRC64;
MGLGKTVQVI SFLAAVLHKK GTREDIENNM PEFLLRSMKK EPSSSTAKKM FLIVAPLSVL
YNWKDELDTW GYFRVTVLHG NRKDNELIRV KQRKCEIALT TYETLRLCLD ELNSLEWSAI
IVDEAHRIKN PKARVTEVMK ALKCNVRIGL TGTILQNNMK ELWCVMDWAV PGLLGSNSYF
KKQFSDPVEH GQRHTATKRE LATGRKAMQR LAKKMSGWFL RRTKTLIKDQ LPKKEDRMVY
CSLTDFQKAV YQTVLETEDV TLILQSSEPC TCSSGRKRRN CCYKTNSHGE TVKTLYLSYL
TVLQKVANHV ALLQAASTSK QQETLIKRIC DQVFSRFPDF VQKTKDAAFE TLSDPKYSGK
MKVLQQLLNH CRKNRDKVLL FSFSTKLLDV LQQYCMASGL DYRRLDGSTK SEERLKIVKE
FNSTQDVNVC LVSTMAGGLG LNFVGANVVV LFDPTWNPAN DLQAIDRAYR IGQCRDVKVL
RLISLGTVEE IMYLRQVYKQ QLHCVVVGSE NAKRYFEAVQ GSKEHQGELF GTHNLFRLRS
QGSCLTRDIL EREGQVEAGI MTATTWLKEG SPAHKPETPT EPDCQDRRGP EQAAEPLAKE
ACGFCSDFSD EDPVGAAGMQ TAKNKAPDSS KASTSPGQLT LLQCGFSKLF ETKCKAVEDS
DGNTASDDES SDEQPICLST EAKVADCGKN QDSLGTSKHQ KLDILNPKEK YIFYKNEKIL
EQNISSKSDD EKTFKNTDKH CILQNVSESE DSDVICPTQY TTERFPNNSI RFKQPLEGSE
DSETERSVKT RNDDGRKTDD RRDGIISKKL SPENTTLKSI VKRKVTSDIS DESDDIEISS
KSKVRKRVTS SLRFKRRKET RKELHRFPKT INKTKQLCAT DEDHNSQFID DYSSSDESLS
VSHFNFSKQS HRPRTIKDRT SFSSKLPSQN KKNSTVMPRK PVKCSNEKVV NQEQSYESMD
KFLDGVREVA YIHSNQNVIG SSKAENHMSR WAAHDVFELK QFSQLPANIA VCTSKTYKEK
VDADTLPHTK KGQQPSEGSI SLPLYISHPV SQKKKKVYRT HQTIFIIGET PKGIRRKQFE
EMASHFNSSS VNEFAKRITS ATSEERQKML RDFYASQYPE VKELFVDSAS EFNNSAFEKG
ERIRKKSEKR KPLVKARLSD SETLSFKDST NKISQIGCPK TYKGKSIKFQ NCHSCREEVF
SNDAETKKSP VSSTREIDSA KNSQASEGAA TSRSLNSESE ARERRFENTV KDPQDLTRTG
VSRKEPLLKL ENKKIENPVL EKTSVSSLLG DTSILDDLFK SHGNSPTQPP KKVLSRPMEK
AKQRPKDFWD ILNEQNDESL CKLTDLAVIE TLCEKAPLAA PSTRREEPAT SLWKSNEKFL
WKKFNSSDTD ENTTSTQSTI
//
