ID A0A2K6TQC0_SAIBB Unreviewed; 150 AA.
AC A0A2K6TQC0;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE SubName: Full=von Hippel-Lindau tumor suppressor {ECO:0000313|Ensembl:ENSSBOP00000021772.1};
GN Name=VHL {ECO:0000313|Ensembl:ENSSBOP00000021772.1};
OS Saimiri boliviensis boliviensis (Bolivian squirrel monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Saimiriinae; Saimiri.
OX NCBI_TaxID=39432 {ECO:0000313|Ensembl:ENSSBOP00000021772.1, ECO:0000313|Proteomes:UP000233220};
RN [1] {ECO:0000313|Ensembl:ENSSBOP00000021772.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the VHL family. {ECO:0000256|ARBA:ARBA00010057}.
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DR AlphaFoldDB; A0A2K6TQC0; -.
DR Ensembl; ENSSBOT00000038615.1; ENSSBOP00000021772.1; ENSSBOG00000027433.1.
DR GeneTree; ENSGT00390000014353; -.
DR Proteomes; UP000233220; Unplaced.
DR CDD; cd05468; pVHL; 1.
DR Gene3D; 1.10.750.10; von Hippel-Lindau disease tumour suppressor, alpha domain; 1.
DR Gene3D; 2.60.40.780; von Hippel-Lindau disease tumour suppressor, beta domain; 1.
DR InterPro; IPR024048; VHL_alpha_dom.
DR InterPro; IPR037139; VHL_alpha_dom_sf.
DR InterPro; IPR024053; VHL_beta_dom.
DR InterPro; IPR037140; VHL_beta_dom_sf.
DR InterPro; IPR036208; VHL_sf.
DR InterPro; IPR022772; VHL_tumour_suppress_b/a_dom.
DR Pfam; PF01847; VHL; 1.
DR Pfam; PF17211; VHL_C; 1.
DR SUPFAM; SSF49468; VHL; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000233220}.
FT DOMAIN 42..93
FT /note="von Hippel-Lindau disease tumour suppressor beta"
FT /evidence="ECO:0000259|Pfam:PF01847"
FT DOMAIN 94..142
FT /note="von Hippel-Lindau disease tumour suppressor alpha"
FT /evidence="ECO:0000259|Pfam:PF17211"
FT REGION 1..44
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 150 AA; 17114 MW; 592CF7A3F039B0A8 CRC64;
MPRRAEVGAE ESGASESGPE ESIPEGPGAE KEMEAGRPRP VLRSVNSREP SQVIFCNRSP
RVVLPVWLNF DGEPQPYPTL PPGTGRRIHS YRVYTLKERC LQVVRSLVKP ENYRRLDIVR
SLYEDLEDHP NVQKDLERLT QEHIANQQMA
//
