ID   A0A2K6TQW8_SAIBB        Unreviewed;       730 AA.
AC   A0A2K6TQW8;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   24-JAN-2024, entry version 23.
DE   SubName: Full=RAP1 GTPase activating protein 2 {ECO:0000313|Ensembl:ENSSBOP00000022051.1};
GN   Name=RAP1GAP2 {ECO:0000313|Ensembl:ENSSBOP00000022051.1};
OS   Saimiri boliviensis boliviensis (Bolivian squirrel monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC   Saimiriinae; Saimiri.
OX   NCBI_TaxID=39432 {ECO:0000313|Ensembl:ENSSBOP00000022051.1, ECO:0000313|Proteomes:UP000233220};
RN   [1] {ECO:0000313|Ensembl:ENSSBOP00000022051.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   RefSeq; XP_003933129.1; XM_003933080.2.
DR   AlphaFoldDB; A0A2K6TQW8; -.
DR   Ensembl; ENSSBOT00000038897.1; ENSSBOP00000022051.1; ENSSBOG00000027571.1.
DR   GeneID; 101041129; -.
DR   KEGG; sbq:101041129; -.
DR   CTD; 23108; -.
DR   GeneTree; ENSGT00940000160935; -.
DR   OrthoDB; 25782at2759; -.
DR   Proteomes; UP000233220; Unplaced.
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.
DR   Gene3D; 6.10.140.210; -; 1.
DR   Gene3D; 3.40.50.11210; Rap/Ran-GAP; 1.
DR   InterPro; IPR035974; Rap/Ran-GAP_sf.
DR   InterPro; IPR000331; Rap/Ran_GAP_dom.
DR   PANTHER; PTHR15711; RAP GTPASE-ACTIVATING PROTEIN; 1.
DR   PANTHER; PTHR15711:SF17; RAP1 GTPASE-ACTIVATING PROTEIN 2; 1.
DR   Pfam; PF21022; Rap-GAP_dimer; 1.
DR   Pfam; PF02145; Rap_GAP; 1.
DR   SUPFAM; SSF111347; Rap/Ran-GAP; 1.
DR   PROSITE; PS50085; RAPGAP; 1.
PE   4: Predicted;
KW   GTPase activation {ECO:0000256|ARBA:ARBA00022468, ECO:0000256|PROSITE-
KW   ProRule:PRU00165}; Reference proteome {ECO:0000313|Proteomes:UP000233220}.
FT   DOMAIN          248..464
FT                   /note="Rap-GAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50085"
FT   REGION          33..53
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          509..533
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          551..730
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        579..616
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        632..689
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   730 AA;  80114 MW;  2FAA0452D7DB4E77 CRC64;
     MFGRKRSVSF GGFGWIDKTM LASLKVKKQD LANSSDVTLP DRPLSPPLTA PPTMKSSEFF
     EMLEKMQGIK LEEQKPGPQK NKDDYIPYPS IDEVVEKGGP YPQVILPQFG GYWIEDPENV
     GTPTSLGSSI CEEEEEDNLS PNTFGYKLEC KGEARAYRRH FLGKDHLNFY CTGSSLGNLI
     LSVKCEEAEG IEYLRIILRS KLKTVHERIP LVGLSKLPSV PQIAKAFCDD AVGLKFNPVL
     YPKASQMIVS YDEHDVNNTF KFGVIYQKAR QTLEEELFGN NEESPAFKEF LDLLGDTITL
     QDFKGFRGGL DVTHGQTGVE SVYTTFRDRE IMFHVSTKLP FTEGDAQQLQ RKRHIGNDIV
     AIIFQEENTP FVPDMIASNF LHAYIVVQVE APGTETPSYK VSVTAREDVP TFGPPLPSPP
     VFQKGAEFRE FLLTKLTNAE NACCKSDKFA KLEDRTRAAL LDNLHDELHA HTQAMLGLGP
     EEDKFENGGH GGFLESFKRA IRVRSHSMET MVGGQKKSHS GGIPGSLSGG ISHNSMEVTK
     TTFSPPVVVA TAKNQSRSPI KRRSGLFPRL HTGSEGQGDS RARCDSVSST PKTPDGGHSS
     QEIKSETSSN PSSPEICPNR EKPFMKLKEN GRAISRSSSS TSSVSSTTGE GEAMEEGDSG
     SSQPSTTSPF KQEVFVYSPS PSSESPSLGA AATPIIMSRS PTDAKSRNSP RSNLKFRFDK
     LSHASSGAGH
//