ID   A0A2K6TRN4_SAIBB        Unreviewed;       248 AA.
AC   A0A2K6TRN4;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   RecName: Full=Apolipoprotein A-I {ECO:0000256|ARBA:ARBA00040759};
GN   Name=APOA1 {ECO:0000313|Ensembl:ENSSBOP00000022315.1};
OS   Saimiri boliviensis boliviensis (Bolivian squirrel monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC   Saimiriinae; Saimiri.
OX   NCBI_TaxID=39432 {ECO:0000313|Ensembl:ENSSBOP00000022315.1, ECO:0000313|Proteomes:UP000233220};
RN   [1] {ECO:0000313|Ensembl:ENSSBOP00000022315.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- FUNCTION: Participates in the reverse transport of cholesterol from
CC       tissues to the liver for excretion by promoting cholesterol efflux from
CC       tissues and by acting as a cofactor for the lecithin cholesterol
CC       acyltransferase (LCAT). As part of the SPAP complex, activates
CC       spermatozoa motility. {ECO:0000256|ARBA:ARBA00037354}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC   -!- SIMILARITY: Belongs to the apolipoprotein A1/A4/E family.
CC       {ECO:0000256|ARBA:ARBA00008788}.
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DR   AlphaFoldDB; A0A2K6TRN4; -.
DR   Ensembl; ENSSBOT00000039162.1; ENSSBOP00000022315.1; ENSSBOG00000027691.1.
DR   GeneTree; ENSGT00950000182929; -.
DR   Proteomes; UP000233220; Unplaced.
DR   GO; GO:0034364; C:high-density lipoprotein particle; IEA:UniProtKB-KW.
DR   GO; GO:0008289; F:lipid binding; IEA:InterPro.
DR   GO; GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
DR   GO; GO:0042157; P:lipoprotein metabolic process; IEA:InterPro.
DR   Gene3D; 1.20.5.20; -; 1.
DR   Gene3D; 6.10.140.380; -; 1.
DR   Gene3D; 1.20.120.20; Apolipoprotein; 1.
DR   InterPro; IPR000074; ApoA_E.
DR   PANTHER; PTHR18976; APOLIPOPROTEIN; 1.
DR   PANTHER; PTHR18976:SF11; APOLIPOPROTEIN A-I; 1.
DR   Pfam; PF01442; Apolipoprotein; 1.
DR   SUPFAM; SSF58113; Apolipoprotein A-I; 1.
PE   3: Inferred from homology;
KW   Cholesterol metabolism {ECO:0000256|ARBA:ARBA00022548};
KW   HDL {ECO:0000256|ARBA:ARBA00022850};
KW   Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW   Lipid transport {ECO:0000256|ARBA:ARBA00023055};
KW   Lipoprotein {ECO:0000256|ARBA:ARBA00023288};
KW   Oxidation {ECO:0000256|ARBA:ARBA00023097};
KW   Palmitate {ECO:0000256|ARBA:ARBA00023139};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233220};
KW   Secreted {ECO:0000256|ARBA:ARBA00022525};
KW   Steroid metabolism {ECO:0000256|ARBA:ARBA00023221};
KW   Sterol metabolism {ECO:0000256|ARBA:ARBA00023166};
KW   Transport {ECO:0000256|ARBA:ARBA00022448}.
SQ   SEQUENCE   248 AA;  28439 MW;  8FC7EFA5BBD36377 CRC64;
     MSRGARGFCM LETHPSHRHS AKLFFSSRSP TALQDESCGA DLGRALPDGL KLLDNWDSLT
     STVNKLREQL GPVTQEFWDN LEKETEQLRQ EMNKDLEEVK AKVQPYLDDF QKKWQEEMNL
     YSQKLEPLRT EFQEGAFQKL QDLREKLRPV AEQVRDRARA HVDTLRTQLA PYSDELRQRL
     ATRLEALKES GATLAEYQAK ASEHLSALGE KAKPAFEDLR QGLLPVLESF KVSFLSALDE
     YAKKLSSQ
//