ID A0A2K6TS04_SAIBB Unreviewed; 408 AA.
AC A0A2K6TS04;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=TNF receptor superfamily member 11b {ECO:0000313|Ensembl:ENSSBOP00000022440.1};
GN Name=TNFRSF11B {ECO:0000313|Ensembl:ENSSBOP00000022440.1};
OS Saimiri boliviensis boliviensis (Bolivian squirrel monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Saimiriinae; Saimiri.
OX NCBI_TaxID=39432 {ECO:0000313|Ensembl:ENSSBOP00000022440.1, ECO:0000313|Proteomes:UP000233220};
RN [1] {ECO:0000313|Ensembl:ENSSBOP00000022440.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00206}.
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DR AlphaFoldDB; A0A2K6TS04; -.
DR Ensembl; ENSSBOT00000039290.1; ENSSBOP00000022440.1; ENSSBOG00000027754.1.
DR GeneTree; ENSGT00940000155167; -.
DR OMA; CENGVQR; -.
DR Proteomes; UP000233220; Unplaced.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd01670; Death; 2.
DR CDD; cd10581; TNFRSF11B; 1.
DR Gene3D; 1.10.533.10; Death Domain, Fas; 1.
DR Gene3D; 2.10.50.10; Tumor Necrosis Factor Receptor, subunit A, domain 2; 3.
DR InterPro; IPR011029; DEATH-like_dom_sf.
DR InterPro; IPR000488; Death_domain.
DR InterPro; IPR001368; TNFR/NGFR_Cys_rich_reg.
DR InterPro; IPR022323; TNFR_11.
DR InterPro; IPR017371; TNFR_11B.
DR PANTHER; PTHR23097; TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER; 1.
DR PANTHER; PTHR23097:SF90; TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 11B; 1.
DR Pfam; PF00531; Death; 1.
DR Pfam; PF00020; TNFR_c6; 4.
DR PIRSF; PIRSF038065; TNFR_11B; 1.
DR PRINTS; PR01961; TNFACTORR11.
DR PRINTS; PR01975; TNFACTORR11B.
DR SMART; SM00005; DEATH; 1.
DR SMART; SM01411; Ephrin_rec_like; 2.
DR SMART; SM00208; TNFR; 4.
DR SUPFAM; SSF47986; DEATH domain; 2.
DR SUPFAM; SSF57586; TNF receptor-like; 2.
DR PROSITE; PS50050; TNFR_NGFR_2; 2.
PE 4: Predicted;
KW Apoptosis {ECO:0000256|ARBA:ARBA00022703};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157,
KW ECO:0000256|PIRSR:PIRSR038065-2};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Reference proteome {ECO:0000313|Proteomes:UP000233220};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 71..112
FT /note="TNFR-Cys"
FT /evidence="ECO:0000259|PROSITE:PS50050"
FT REPEAT 71..112
FT /note="TNFR-Cys"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT REPEAT 113..149
FT /note="TNFR-Cys"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT DOMAIN 113..149
FT /note="TNFR-Cys"
FT /evidence="ECO:0000259|PROSITE:PS50050"
FT SITE 407
FT /note="Involved in dimerization"
FT /evidence="ECO:0000256|PIRSR:PIRSR038065-1"
FT DISULFID 48..61
FT /evidence="ECO:0000256|PIRSR:PIRSR038065-2"
FT DISULFID 51..69
FT /evidence="ECO:0000256|PIRSR:PIRSR038065-2"
FT DISULFID 72..87
FT /evidence="ECO:0000256|PIRSR:PIRSR038065-2,
FT ECO:0000256|PROSITE-ProRule:PRU00206"
FT DISULFID 90..104
FT /evidence="ECO:0000256|PIRSR:PIRSR038065-2"
FT DISULFID 94..112
FT /evidence="ECO:0000256|PIRSR:PIRSR038065-2,
FT ECO:0000256|PROSITE-ProRule:PRU00206"
FT DISULFID 114..125
FT /evidence="ECO:0000256|PIRSR:PIRSR038065-2"
FT DISULFID 131..149
FT /evidence="ECO:0000256|PIRSR:PIRSR038065-2,
FT ECO:0000256|PROSITE-ProRule:PRU00206"
FT DISULFID 152..167
FT /evidence="ECO:0000256|PIRSR:PIRSR038065-2"
FT DISULFID 173..192
FT /evidence="ECO:0000256|PIRSR:PIRSR038065-2"
SQ SEQUENCE 408 AA; 47031 MW; C0BECFF6D0A08B1D CRC64;
LFGIICCNYF FTYYCLHFLD ISIKWTTQET FPPKYLHYDA ETSHQLLCDK CPPGTYLKQH
CTAKWKTVCA PCPDHYYTDS WHTSDECLYC SPVCKELQYI KQECNRTHNR VCECKEGRYL
EVEFCLKHRS CPPGFGVVQA GTPERNTVCR RCPDGFFSNE TSSKAPCRKH TNCSVFGLLL
TQKGNATHDN VCSGNNESTQ KCGIDVTLCE EAFFRFAVPT KFTPNWLSVL VDNLPGTKVN
AESVERIKRQ HSSQEQTFQL LKLWKHQNKD QDMVKKIIQD IDLCENSVLR HIGHANLTFE
QLRSLMESLP GKKVGAEDIE KTTKACKSSE QILKLLSLWR IKNGDQDTLK GLMHALKHSK
TYHFPKTVTQ SLKKTIRFLH SFTMYKLYQK LFLEMIGNQV QSVKISCL
//
