ID A0A2K6TXY0_SAIBB Unreviewed; 1905 AA.
AC A0A2K6TXY0;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=SH3 domain-containing protein {ECO:0000259|PROSITE:PS50002};
OS Saimiri boliviensis boliviensis (Bolivian squirrel monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Saimiriinae; Saimiri.
OX NCBI_TaxID=39432 {ECO:0000313|Ensembl:ENSSBOP00000024532.1, ECO:0000313|Proteomes:UP000233220};
RN [1] {ECO:0000313|Ensembl:ENSSBOP00000024532.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004389}; Single-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004389}. Membrane
CC {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004167}.
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DR RefSeq; XP_010339225.1; XM_010340923.1.
DR Ensembl; ENSSBOT00000041392.1; ENSSBOP00000024532.1; ENSSBOG00000028739.1.
DR GeneTree; ENSGT00950000182767; -.
DR OrthoDB; 5406966at2759; -.
DR Proteomes; UP000233220; Unplaced.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR CDD; cd11893; SH3_MIA3; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR23158; MELANOMA INHIBITORY ACTIVITY-RELATED; 1.
DR PANTHER; PTHR23158:SF54; TRANSPORT AND GOLGI ORGANIZATION PROTEIN 1 HOMOLOG; 1.
DR Pfam; PF07653; SH3_2; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Reference proteome {ECO:0000313|Proteomes:UP000233220};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..1905
FT /note="SH3 domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014387062"
FT DOMAIN 45..107
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 157..192
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 204..223
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 338..361
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 396..439
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 531..615
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 675..728
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 766..897
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1092..1119
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1422..1445
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1643..1905
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1222..1291
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1334..1396
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1494..1641
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 340..361
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 531..549
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 552..595
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 675..695
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 774..799
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 806..829
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 830..844
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 847..887
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1657..1673
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1726..1749
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1761..1811
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1854..1876
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1885..1905
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1905 AA; 213895 MW; 146A7CE3F870356A CRC64;
MAVVPGLLFW LFVVGLPWRV PGQPDPSTGR RFSDDKLCAD DECSMLMYRG EALEDFTGPD
CRFVNFKKGD PVYVYYKLAR GSPEVWAGSV GRLFGYFPKD LIQVVHEYTK EELQVPTDET
DFVCFDGGRD EFDNYNVEEL LGFLELYNSA TRDSEKAIEK MSQDVEKKPE LSKEREPELE
PVEANSEEND RVFSEKAKDL QEQFTAQKHH PHTNSQADHA QGEQPPFEAF EEMLQDKLKV
PESENNKTSN SSQVSNEQDK IDAYKLLKKE MTLDLKTKFG STADALVSDD ETTRLVTSLE
DDFDEDLDAE YYAVGKEDEE NQDFVKLPLL TFTDGEDIKT PAKSGVEKYS TDKEQNSNEE
DKLELTVHLG IKNDDKNILT TWGDTIFSLV TGGEEKTDTL DLESSNSEEE KDDDALVPES
KRGKPQSTAD YSDPDNVDDG LLIADIPKTN NDKGPEVNTE HHIKGKGWEV QESKKGLIQD
ETELEDEKQE GMTVYSFTHS NNLNSMPAGE KGKDTLKSAF DDKENDLKGA AIHISKGMPR
EEKPGEQILE GGSESESAQK AAGNGMNDRR IQQESLGTAP VTGDNHPNAS RDSVEGDASV
NGAKPHTLPV EHQREEFKEE LVLKTQNQPK FSSPDEIGLP RELEEKAPIL GRNLSWQQER
DVAATVNKQI SEKIRLSEGE AKEDSSDEEV FHHKAMQGAQ EVGQTDESDS TGEPALLSEA
EEDDYPPEEL LEDENAVSAK WSKEENPGIQ GRQFDVNLQV PERAVLGTTN PDPEIEESKQ
ETSNILDSEK KRETAAKGVK TGAREPYTMV EKERPPVDEK AHRPSEGSDF SDSMKTQTPE
LGEVFQNKDS DYLKNDNPEE HLKTSGLAEK PEGELSKEDH ENTEKHMGTE SQGSAAADLE
DDLFRWTPHT TVEPEYSDKW ENLPIISSFF KEQQSLQRFQ KYFNVHELES LLQEMSSKLK
SAQQESLPYN VEKVLDKVFR ASESQILSIA EKMLDTRVAE NRDLGMKENN VFEEAAVLDD
IQDLIYFVRY KHSTAEETAI LVMAPPLDEG LGGTMEEMQP PHEDNVSQEN TAELNVQVPE
EPAHLDQTVM RNTHASEVSP KPNTEKDLDP VLGPVTTEDP PMYAVEANKQ LEMVAEEPAS
VTPLENAILL ICSFTLYLTK LLVSTLPDDV QPGPDFYGLP WKPVLITAFL GIASVVVFFW
RTILVVKSKV YQVTEQQISE KLKIIMKENT ELVQKLSNYE QKIKESKKHV QETRKQNMIL
SDEAIKFKDK IKTLEKNNEI LGDRAKNLRV MLESEREQNV KNQDLISENK KSIEKLKDVI
SMNASEFSEV QIALNEAKLS EEKVKSECHR VQEENARLKK KKEQLQLEIE DWSKLHAELS
EQIKSFEKSQ KDLEVALTHK DDNINALTNC ITQLNRLECE SESEGQNKGG NDSDELANGE
VAGDRNEKMK NQIKQLMDVS RTQTAISVVE EDLKHLQLKL RASMSTKCNL EDQIKKLEDD
RNSLQSAKDG LEDECRTLRQ KVEILNELYQ QKEMALQKKL SQEEYERQER EQRLSAADEK
AVSAAEEVKT YKRRIEEMED ELQKTERLFK NQIATHEKKA HENWLKARAA ERAIAEEKRE
AANLRHKLLE LTQKMAMLQE EPVIVKPMPG RPNTQNPPRR GPLSQNGSFG PSPVSGGECS
PPPTVEPPVR LLSATLSRRD MPRSEFGSVD GPLPHPRWSA EASGKPSPSD PGSGTAAMMN
NSSRGSSPTR MMDEGKVNMT PKGPPPFPGV PLMSTPMGGP VPPPIRYGPP PQLCGPFGPR
PIPPPFGPGM RPPLGLREFA PGKRDLPLHP REFLPGHAPF RPLGPLGPRE YFIPGTRLPP
PTHVPQDYPP PPAARDLLQP GSREEPPPAS QSTSQDCSPA LKQSP
//
