ID   A0A2K6U0V7_SAIBB        Unreviewed;       323 AA.
AC   A0A2K6U0V7;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   RecName: Full=Mitochondrial-processing peptidase subunit alpha {ECO:0000256|ARBA:ARBA00016741};
DE   AltName: Full=Alpha-MPP {ECO:0000256|ARBA:ARBA00030006};
GN   Name=PMPCA {ECO:0000313|Ensembl:ENSSBOP00000025548.1};
OS   Saimiri boliviensis boliviensis (Bolivian squirrel monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC   Saimiriinae; Saimiri.
OX   NCBI_TaxID=39432 {ECO:0000313|Ensembl:ENSSBOP00000025548.1, ECO:0000313|Proteomes:UP000233220};
RN   [1] {ECO:0000313|Ensembl:ENSSBOP00000025548.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- FUNCTION: Substrate recognition and binding subunit of the essential
CC       mitochondrial processing protease (MPP), which cleaves the
CC       mitochondrial sequence off newly imported precursors proteins.
CC       {ECO:0000256|ARBA:ARBA00002123}.
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DR   AlphaFoldDB; A0A2K6U0V7; -.
DR   Ensembl; ENSSBOT00000042415.1; ENSSBOP00000025548.1; ENSSBOG00000029246.1.
DR   GeneTree; ENSGT00940000156724; -.
DR   Proteomes; UP000233220; Unplaced.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   Gene3D; 3.30.830.10; Metalloenzyme, LuxS/M16 peptidase-like; 2.
DR   InterPro; IPR011249; Metalloenz_LuxS/M16.
DR   InterPro; IPR011765; Pept_M16_N.
DR   InterPro; IPR007863; Peptidase_M16_C.
DR   PANTHER; PTHR11851; METALLOPROTEASE; 1.
DR   PANTHER; PTHR11851:SF49; MITOCHONDRIAL-PROCESSING PEPTIDASE SUBUNIT ALPHA; 1.
DR   Pfam; PF00675; Peptidase_M16; 1.
DR   Pfam; PF05193; Peptidase_M16_C; 1.
DR   SUPFAM; SSF63411; LuxS/MPP-like metallohydrolase; 2.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000233220}.
FT   DOMAIN          46..95
FT                   /note="Peptidase M16 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00675"
FT   DOMAIN          168..229
FT                   /note="Peptidase M16 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF05193"
SQ   SEQUENCE   323 AA;  37308 MW;  1DA1B7EE27DF74DE CRC64;
     MKQNILVELL TFWKNWHFRL LLDLTAKMKF CLHWKSMGVF VTARHQDEEV EMTRMAVQFE
     LEDLNMRPDP EPLLTEMIHE AAYRENTVGL HRFCPAENIA KMSREVLHSY LRNYYTPDRM
     VLAGVGVEHE QLVGCAHKYL LGVQPAWGSV EAVDVDRSVA QYTGGIVKHH WMYNATSYHH
     SYEDTGLLCI HASADPRQVR EMVEIITKEF ILMGGTVDEV ELERAKTQLM SMLMMNLESR
     PVIFEDVGRQ VLATRSRKLP HELCTLIRNV KPEDVKRVAS KMLRGKPAVA ALGDLTDLPT
     YEHIQTALSS KDGRLPRMYR LFR
//