ID   A0A2K6U1P5_SAIBB        Unreviewed;      1094 AA.
AC   A0A2K6U1P5;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   RecName: Full=PDZ domain-containing protein {ECO:0000259|PROSITE:PS50106};
OS   Saimiri boliviensis boliviensis (Bolivian squirrel monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC   Saimiriinae; Saimiri.
OX   NCBI_TaxID=39432 {ECO:0000313|Ensembl:ENSSBOP00000025791.1, ECO:0000313|Proteomes:UP000233220};
RN   [1] {ECO:0000313|Ensembl:ENSSBOP00000025791.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cell junction, tight junction
CC       {ECO:0000256|ARBA:ARBA00004435}. Endomembrane system
CC       {ECO:0000256|ARBA:ARBA00004308}.
CC   -!- SIMILARITY: Belongs to the PAR3 family.
CC       {ECO:0000256|ARBA:ARBA00005358}.
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DR   AlphaFoldDB; A0A2K6U1P5; -.
DR   STRING; 39432.ENSSBOP00000025791; -.
DR   Ensembl; ENSSBOT00000042660.1; ENSSBOP00000025791.1; ENSSBOG00000029272.1.
DR   GeneTree; ENSGT00950000183214; -.
DR   Proteomes; UP000233220; Unplaced.
DR   GO; GO:0005923; C:bicellular tight junction; IEA:UniProtKB-SubCell.
DR   GO; GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.
DR   CDD; cd00992; PDZ_signaling; 3.
DR   Gene3D; 2.30.42.10; -; 3.
DR   InterPro; IPR021922; Par3/HAL_N.
DR   InterPro; IPR001478; PDZ.
DR   InterPro; IPR036034; PDZ_sf.
DR   PANTHER; PTHR16484:SF10; PARTITIONING DEFECTIVE 3 HOMOLOG; 1.
DR   PANTHER; PTHR16484; PARTITIONING DEFECTIVE 3 RELATED; 1.
DR   Pfam; PF12053; Par3_HAL_N_term; 1.
DR   Pfam; PF00595; PDZ; 3.
DR   SMART; SM00228; PDZ; 3.
DR   SUPFAM; SSF50156; PDZ domain-like; 3.
DR   PROSITE; PS50106; PDZ; 3.
PE   3: Inferred from homology;
KW   Cell junction {ECO:0000256|ARBA:ARBA00022427};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233220};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Tight junction {ECO:0000256|ARBA:ARBA00022427}.
FT   DOMAIN          205..281
FT                   /note="PDZ"
FT                   /evidence="ECO:0000259|PROSITE:PS50106"
FT   DOMAIN          384..469
FT                   /note="PDZ"
FT                   /evidence="ECO:0000259|PROSITE:PS50106"
FT   DOMAIN          500..575
FT                   /note="PDZ"
FT                   /evidence="ECO:0000259|PROSITE:PS50106"
FT   REGION          89..201
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          340..363
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          759..781
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          821..893
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          927..954
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        89..121
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        122..136
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        137..158
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        166..185
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        853..871
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        872..893
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1094 AA;  121919 MW;  F9ECC6A7F88247DA CRC64;
     MKVTVCFGRT WVVVPCGDGH MKVFSLIQQA VTRYRKAIAK DPNYWIQVHR LEHGDGGILD
     LDDILCDVNM PLHVRCSSDP ALIGLSTSIS DNNFSSEEPS RKNPTRWSTT AGFLKQNTAG
     SPKTCDRKKD ENYRSLPRDT SNWSNQFQRE NARSSLSASH PMVGKWLEKQ EQDEDGTEEG
     SSRVEPVGHA DTGLENIPNF SPDDTVKLVQ VPNDGGPLGI HVVPFSARGG RTLGVLVKRL
     EKGGKAEHEN FFHENDCIIR INDGDLRNRR FEQAQHMFRQ AVRTPIIWFH VVPAANKEQY
     EQLSQSEKNN YYSSRFSPYS QYIDNRSVNS AGLHAVQRAP RLNHPPDAHP WGKSPSAPAP
     APQNVFSTTI NSGYNTKKIG KRLNIQLKKG TEGLGFSITS RDVTIGGSAP IYVKNILPRG
     AAIQDGRLKA GDRLTEVNGV DLAGKSQEEV VSLLRSTKME GTVSLLVFRQ EDAFHPRELK
     AEDEDIVLTP DGTREFLTFE VPLNDSGSAG LGVSVKGNRS KENHADLGIF VKSIINGGAA
     SKDGRLRVND QLIAVNGESL LGKTNQDAME TLRRSMSTEG MIQLIVLKSP GSPPGPELPI
     ETALDDRERK ISHSLYGGIE GLDESPSRNA ALSRIMGKYQ LSPTVNMPQD DTVIIEDDRL
     PVLPPHLSDQ SSSSSHDDVG FVTTDAGTWA KAAISDSADC SLNPDVDPVL TFQREGFGRQ
     SMSEKRTKQF SDASQLDFFK TQKSKSMDLG IADETKLNTV DDQKAGSPSR DVGPSLGLKK
     SSSLESLQTT VAAVTLNGDI PFHRPRPRMI RGRGCNESFR TAIDKSYDKP AADDDDEGME
     TLEEDTEESS RSGRESVSTA SDQPSHSLER QMNGNQEKEE RDKEKDKMKA KKGMLKGLGD
     MFGFGKHRKD DKIEKTGKIK IQESFTSEEE RIRMKQEQER IQAKTREFRE RQARERDYAE
     IQDFHRTFGC DDELMYGGVS SYEGSMALNA RPQSPREGHL MDALYAQVMR AAVLSYFYPS
     QPDRYQWRAT GETEPNHHPA ETKSPSTNVA AMMQLAEKAI YKRVHNTQEK SKQRYRYIKK
     KSQMGTLKQK YTML
//