ID   A0A2K6U5V8_SAIBB        Unreviewed;       734 AA.
AC   A0A2K6U5V8;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=Stromal interaction molecule 2 {ECO:0000313|Ensembl:ENSSBOP00000027250.1};
GN   Name=STIM2 {ECO:0000313|Ensembl:ENSSBOP00000027250.1};
OS   Saimiri boliviensis boliviensis (Bolivian squirrel monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC   Saimiriinae; Saimiri.
OX   NCBI_TaxID=39432 {ECO:0000313|Ensembl:ENSSBOP00000027250.1, ECO:0000313|Proteomes:UP000233220};
RN   [1] {ECO:0000313|Ensembl:ENSSBOP00000027250.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC       pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
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DR   AlphaFoldDB; A0A2K6U5V8; -.
DR   STRING; 39432.ENSSBOP00000027250; -.
DR   Ensembl; ENSSBOT00000044126.1; ENSSBOP00000027250.1; ENSSBOG00000030023.1.
DR   GeneTree; ENSGT00390000000214; -.
DR   Proteomes; UP000233220; Unplaced.
DR   GO; GO:0005783; C:endoplasmic reticulum; IEA:Ensembl.
DR   GO; GO:0005886; C:plasma membrane; IEA:Ensembl.
DR   GO; GO:0005246; F:calcium channel regulator activity; IEA:Ensembl.
DR   GO; GO:0005509; F:calcium ion binding; IEA:Ensembl.
DR   GO; GO:0015279; F:store-operated calcium channel activity; IEA:Ensembl.
DR   GO; GO:0006874; P:intracellular calcium ion homeostasis; IEA:Ensembl.
DR   GO; GO:0051928; P:positive regulation of calcium ion transport; IEA:Ensembl.
DR   CDD; cd09574; SAM_STIM2; 1.
DR   CDD; cd11722; SOAR; 1.
DR   Gene3D; 1.10.238.180; -; 1.
DR   Gene3D; 1.10.287.3550; -; 1.
DR   Gene3D; 1.20.5.340; -; 1.
DR   Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR   InterPro; IPR001660; SAM.
DR   InterPro; IPR013761; SAM/pointed_sf.
DR   InterPro; IPR032393; SOAR.
DR   InterPro; IPR037608; STIM.
DR   InterPro; IPR037610; STIM2_SAM.
DR   PANTHER; PTHR15136:SF2; STROMAL INTERACTION MOLECULE 2; 1.
DR   PANTHER; PTHR15136; STROMAL INTERACTION MOLECULE HOMOLOG; 1.
DR   Pfam; PF07647; SAM_2; 1.
DR   Pfam; PF16533; SOAR; 1.
DR   SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR   PROSITE; PS50105; SAM_DOMAIN; 1.
PE   4: Predicted;
KW   Calcium {ECO:0000256|ARBA:ARBA00022837};
KW   Calcium transport {ECO:0000256|ARBA:ARBA00022568};
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233220};
KW   Signal {ECO:0000256|ARBA:ARBA00022729};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989};
KW   Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   DOMAIN          124..182
FT                   /note="SAM"
FT                   /evidence="ECO:0000259|PROSITE:PS50105"
FT   REGION          469..547
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          673..734
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          243..277
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        492..516
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        673..695
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   734 AA;  83780 MW;  3ACB540F0B8F48C3 CRC64;
     MLNRIWLGGR RESFGVVRTR ERKGKTKAWR WDRKPGEKDP CMSLSPPCFT EEDRFSLEAL
     QTIHKQMDDD KDGGIEVDES DEFIREDMKY KDATNKHSHL HREDKHITVE DLWKRWKTSE
     VHNWTLEDTL QWLIEFVELP QYEKNFRDNN VKGTTLPRIA VHEPSFMISQ LKISDRSHRQ
     KLQLKALDVV LFGPITRPPH NWMKDFILTV SIVIGVGGCW FAYTQNKTSK EHVAKMMKDL
     ESLQTAEQSL MDLQERLDKA QEENRNVAVE KQNLERKMMD EINYAKEEAC RLRELREGAE
     CELSRRQYAE QELEQVRMAL KKAEKEFELR SSWSVPDALQ KWLQLTHEVE VQYYNIKRQN
     AEMQLAIAKD EAEKIKKKRS TVFGTLHVAH SSSLDEVDHK ILEAKKALSE LTTCLRERLF
     RWQQIEKICG FQIAHNSGLP SLTSSLYSDH SWVVMPRVSI PPYPIAGGVD DLDEDTPPIV
     SQFPGTMAKP PGSLARSSSL CRSRRSIVQS SPQPQRAQLP PHAPHPSQSR HPHHPQHTPH
     SLASPDPDIL SVSSCPALYR NEEEEEAIYF SAEKQWEVPD TASECDSLNS SIGRKQSPPL
     SLEIYQTLSP RKISRDEVSL EDSSRGDSPV TVDVSWGSPD CVGLTETKSM IFSPASKVYN
     GILEKSCSMN QLSSGIPVPK PRHTSCSSAG NDSKPVQEAP SVARISSIPH DLCHNGEKSK
     KPSKIKSLFK KKSK
//