ID A0A2K6U635_SAIBB Unreviewed; 385 AA.
AC A0A2K6U635;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE RecName: Full=Transcription factor {ECO:0000256|PIRNR:PIRNR009404};
GN Name=TFDP2 {ECO:0000313|Ensembl:ENSSBOP00000027364.1};
OS Saimiri boliviensis boliviensis (Bolivian squirrel monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Saimiriinae; Saimiri.
OX NCBI_TaxID=39432 {ECO:0000313|Ensembl:ENSSBOP00000027364.1, ECO:0000313|Proteomes:UP000233220};
RN [1] {ECO:0000313|Ensembl:ENSSBOP00000027364.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PIRNR:PIRNR009404,
CC ECO:0000256|RuleBase:RU003796}.
CC -!- SIMILARITY: Belongs to the E2F/DP family.
CC {ECO:0000256|ARBA:ARBA00010940, ECO:0000256|PIRNR:PIRNR009404,
CC ECO:0000256|RuleBase:RU003796}.
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DR RefSeq; XP_010328712.1; XM_010330410.1.
DR AlphaFoldDB; A0A2K6U635; -.
DR Ensembl; ENSSBOT00000044240.1; ENSSBOP00000027364.1; ENSSBOG00000029977.1.
DR GeneID; 101045140; -.
DR CTD; 7029; -.
DR GeneTree; ENSGT00940000157909; -.
DR OrthoDB; 1343784at2759; -.
DR Proteomes; UP000233220; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005667; C:transcription regulator complex; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0051726; P:regulation of cell cycle; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd14458; DP_DD; 1.
DR Gene3D; 1.20.140.80; Transcription factor DP; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR037241; E2F-DP_heterodim.
DR InterPro; IPR003316; E2F_WHTH_DNA-bd_dom.
DR InterPro; IPR038168; TF_DP_C_sf.
DR InterPro; IPR014889; Transc_factor_DP_C.
DR InterPro; IPR015648; Transcrpt_fac_DP.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR12548; TRANSCRIPTION FACTOR DP; 1.
DR PANTHER; PTHR12548:SF5; TRANSCRIPTION FACTOR DP-2; 1.
DR Pfam; PF08781; DP; 1.
DR Pfam; PF02319; E2F_TDP; 1.
DR PIRSF; PIRSF009404; Transcription_factor_DP; 1.
DR SMART; SM01138; DP; 1.
DR SMART; SM01372; E2F_TDP; 1.
DR SUPFAM; SSF144074; E2F-DP heterodimerization region; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE 3: Inferred from homology;
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW DNA-binding {ECO:0000256|PIRNR:PIRNR009404, ECO:0000256|RuleBase:RU003796};
KW Nucleus {ECO:0000256|PIRNR:PIRNR009404, ECO:0000256|RuleBase:RU003796};
KW Reference proteome {ECO:0000313|Proteomes:UP000233220};
KW Transcription {ECO:0000256|PIRNR:PIRNR009404,
KW ECO:0000256|RuleBase:RU003796};
KW Transcription regulation {ECO:0000256|PIRNR:PIRNR009404,
KW ECO:0000256|RuleBase:RU003796}.
FT DOMAIN 66..147
FT /note="E2F/DP family winged-helix DNA-binding"
FT /evidence="ECO:0000259|SMART:SM01372"
FT DOMAIN 154..298
FT /note="Transcription factor DP C-terminal"
FT /evidence="ECO:0000259|SMART:SM01138"
FT REGION 348..385
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 348..365
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 369..385
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 385 AA; 42816 MW; 55472B8308ED88D8 CRC64;
MIISTPQRLT SSGSVLIGSP YTPAPAMVTQ THIAEATGWV PGDRKRAREF IDSDFSESKR
SKKGDKNGKG LRHFSMKVCE KVQRKGTTSY NEVADELVSE FTNSNNHLAA DSAYDQKNIR
RRVYDALNVL MAMNIISKEK KEIKWIGLPT NSAQECQNLE IEKQRRIERI KQKRAQLQEL
LLQQIAFKNL VQRNRQNEQQ NQGPPALNST IQLPFIIINT SRKTVIDCSI SSDKFEYLFN
FDNTFEIHDD IEVLKRMGMS FGLESGKCSL EDLKLAKSLV PKALEGYITD ISTGPSWLNQ
GLLLNSTQSG SNLDLTTGAT LPQSSVNQGL CLDAEVALAT GQFLAPNSHQ SSSAASHCSE
SRGETPCSFN DEDEEDDEED SSSPE
//
