ID   A0A2K6U8F7_SAIBB        Unreviewed;       553 AA.
AC   A0A2K6U8F7;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   RecName: Full=Translation initiation factor eIF2B subunit delta {ECO:0000256|ARBA:ARBA00044147};
DE   AltName: Full=eIF2B GDP-GTP exchange factor subunit delta {ECO:0000256|ARBA:ARBA00044356};
GN   Name=EIF2B4 {ECO:0000313|Ensembl:ENSSBOP00000028202.1};
OS   Saimiri boliviensis boliviensis (Bolivian squirrel monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC   Saimiriinae; Saimiri.
OX   NCBI_TaxID=39432 {ECO:0000313|Ensembl:ENSSBOP00000028202.1, ECO:0000313|Proteomes:UP000233220};
RN   [1] {ECO:0000313|Ensembl:ENSSBOP00000028202.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC       {ECO:0000256|ARBA:ARBA00004514}.
CC   -!- SIMILARITY: Belongs to the eIF-2B alpha/beta/delta subunits family.
CC       {ECO:0000256|ARBA:ARBA00007251, ECO:0000256|RuleBase:RU003814}.
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DR   AlphaFoldDB; A0A2K6U8F7; -.
DR   STRING; 39432.ENSSBOP00000028202; -.
DR   Ensembl; ENSSBOT00000045081.1; ENSSBOP00000028202.1; ENSSBOG00000030402.1.
DR   GeneTree; ENSGT00550000075009; -.
DR   Proteomes; UP000233220; Unplaced.
DR   GO; GO:0005851; C:eukaryotic translation initiation factor 2B complex; IEA:Ensembl.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:Ensembl.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:Ensembl.
DR   GO; GO:0002183; P:cytoplasmic translational initiation; IEA:Ensembl.
DR   GO; GO:0042552; P:myelination; IEA:Ensembl.
DR   GO; GO:0014003; P:oligodendrocyte development; IEA:Ensembl.
DR   GO; GO:0001541; P:ovarian follicle development; IEA:Ensembl.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; IEA:Ensembl.
DR   InterPro; IPR000649; IF-2B-related.
DR   InterPro; IPR042529; IF_2B-like_C.
DR   InterPro; IPR037171; NagB/RpiA_transferase-like.
DR   PANTHER; PTHR10233; TRANSLATION INITIATION FACTOR EIF-2B; 1.
DR   PANTHER; PTHR10233:SF14; TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT DELTA; 1.
DR   Pfam; PF01008; IF-2B; 1.
DR   SUPFAM; SSF100950; NagB/RpiA/CoA transferase-like; 1.
PE   3: Inferred from homology;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Initiation factor {ECO:0000256|ARBA:ARBA00022540};
KW   Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233220}.
FT   REGION          1..170
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        10..28
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        115..139
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   553 AA;  60867 MW;  6C3FD0F9421EFE5C CRC64;
     MPTQQPAAPS TRAPKPSRSL SGSLCALFSD ADSGSGMKAE LPPGPGAVGR EMTKEEKLQL
     RKEKKQQKKK RKEEKVAEPE TGSAVSAAQC QVGPTRELPE SGIQLGTTGE KVPAGRSKAE
     LRAERRAKQE AERALKQARK EQGGPPPKAC PTTSSTAGET PSGVKHLPEY PQVDDLLLRR
     LVKKPERQQV PTRKDYGSKV SLFSHLPQYS RQNSLTQFMS IPSSVIHPAM VRLGLQYSQG
     LVSGSNARCI ALLRALQQVI QDYTTPPNEE LSRDLVNKLK PYMSFVRCAE FFLTQCRPLS
     ASMHNAIKFL NKEITGVSSS KREEEAKSEL RAAIDRYVQE KIVLAAQAIS RFAYKKISNG
     DVILVYGCSS LVSRILQEAW IEGRQFRVVV VDSRPRLEGR HMLRSLVRAG VPASYLLIPA
     ASYVLPEVSK VLLGAHALLA NGSVMSRVGT AQLALVARAH NVPVLVCCET YKFCERVQTD
     AFVSNELDDP DDLQYKRGEH VTLANWQNHT SLRLLNLVYD VTPPELVDLV ITELGMIPCS
     SVPVVLRVKS SDQ
//