ID A0A2K6U955_SAIBB Unreviewed; 305 AA.
AC A0A2K6U955;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=CD300a molecule {ECO:0000313|Ensembl:ENSSBOP00000028429.1};
GN Name=CD300A {ECO:0000313|Ensembl:ENSSBOP00000028429.1};
OS Saimiri boliviensis boliviensis (Bolivian squirrel monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Saimiriinae; Saimiri.
OX NCBI_TaxID=39432 {ECO:0000313|Ensembl:ENSSBOP00000028429.1, ECO:0000313|Proteomes:UP000233220};
RN [1] {ECO:0000313|Ensembl:ENSSBOP00000028429.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004251};
CC Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004251}.
CC Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane
CC protein {ECO:0000256|ARBA:ARBA00004479}.
CC -!- SIMILARITY: Belongs to the CD300 family.
CC {ECO:0000256|ARBA:ARBA00043958}.
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DR RefSeq; XP_003931818.1; XM_003931769.2.
DR STRING; 39432.ENSSBOP00000028425; -.
DR Ensembl; ENSSBOT00000045305.1; ENSSBOP00000028425.1; ENSSBOG00000030593.1.
DR Ensembl; ENSSBOT00000045309.1; ENSSBOP00000028429.1; ENSSBOG00000030593.1.
DR GeneID; 101049688; -.
DR KEGG; sbq:101049688; -.
DR CTD; 11314; -.
DR GeneTree; ENSGT00940000163943; -.
DR OMA; YANMELQ; -.
DR OrthoDB; 5360419at2759; -.
DR Proteomes; UP000233220; Unplaced.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008429; F:phosphatidylethanolamine binding; IEA:Ensembl.
DR GO; GO:0001786; F:phosphatidylserine binding; IEA:Ensembl.
DR GO; GO:0038023; F:signaling receptor activity; IEA:Ensembl.
DR GO; GO:0030889; P:negative regulation of B cell proliferation; IEA:Ensembl.
DR GO; GO:0050859; P:negative regulation of B cell receptor signaling pathway; IEA:Ensembl.
DR GO; GO:1902567; P:negative regulation of eosinophil activation; IEA:Ensembl.
DR GO; GO:2000417; P:negative regulation of eosinophil migration; IEA:Ensembl.
DR GO; GO:0048147; P:negative regulation of fibroblast proliferation; IEA:Ensembl.
DR GO; GO:0033007; P:negative regulation of mast cell activation involved in immune response; IEA:Ensembl.
DR GO; GO:0043305; P:negative regulation of mast cell degranulation; IEA:Ensembl.
DR GO; GO:0034125; P:negative regulation of MyD88-dependent toll-like receptor signaling pathway; IEA:Ensembl.
DR GO; GO:1902564; P:negative regulation of neutrophil activation; IEA:Ensembl.
DR GO; GO:0051134; P:negative regulation of NK T cell activation; IEA:Ensembl.
DR GO; GO:0060101; P:negative regulation of phagocytosis, engulfment; IEA:Ensembl.
DR GO; GO:0050856; P:regulation of T cell receptor signaling pathway; IEA:Ensembl.
DR CDD; cd05716; IgV_pIgR_like; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR013106; Ig_V-set.
DR PANTHER; PTHR11860:SF116; CMRF35-LIKE MOLECULE 8; 1.
DR PANTHER; PTHR11860; POLYMERIC-IMMUNOGLOBULIN RECEPTOR; 1.
DR Pfam; PF15330; SIT; 1.
DR Pfam; PF07686; V-set; 1.
DR SMART; SM00409; IG; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Reference proteome {ECO:0000313|Proteomes:UP000233220};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 18..305
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014561843"
FT TRANSMEM 182..202
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 13..124
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 279..305
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 287..305
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 305 AA; 33906 MW; 5EF28AF6CA3F17CA CRC64;
MWLPWTLLLL WVPGCFALSG PSTVAGPLGG SLSVQCGYEE EHRTLNKYWC RVRWTIRCDK
IVETKESAGK LRNSRVSIRD HPANLSFTVT LENLTEDDAG TYWCGVDTPL LRDLHDPIIK
VEVSVFPAST SATLTSVTAA RTSAITTAFP PVPSTTLLTV SATHSTGIQG DNEEVVNFKL
PLLLSLLALL LLLLVGASLL VWRMFQKRVK AGEHSELSQN HRQAVEESEQ HYANLELLTW
PLQEEPALPT QVEVEYSTVA APREELHYAS VVFDSQSQNS NANRIAAQRP REEEPDSNYS
VIRKT
//
