ID   A0A2K6U9Q8_SAIBB        Unreviewed;       353 AA.
AC   A0A2K6U9Q8;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   24-JAN-2024, entry version 22.
DE   SubName: Full=Karyopherin subunit alpha 3 {ECO:0000313|Ensembl:ENSSBOP00000028647.1};
GN   Name=KPNA3 {ECO:0000313|Ensembl:ENSSBOP00000028647.1};
OS   Saimiri boliviensis boliviensis (Bolivian squirrel monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC   Saimiriinae; Saimiri.
OX   NCBI_TaxID=39432 {ECO:0000313|Ensembl:ENSSBOP00000028647.1, ECO:0000313|Proteomes:UP000233220};
RN   [1] {ECO:0000313|Ensembl:ENSSBOP00000028647.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the importin alpha family.
CC       {ECO:0000256|ARBA:ARBA00010394}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; A0A2K6U9Q8; -.
DR   Ensembl; ENSSBOT00000045527.1; ENSSBOP00000028647.1; ENSSBOG00000030689.1.
DR   GeneTree; ENSGT01050000244891; -.
DR   Proteomes; UP000233220; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0061608; F:nuclear import signal receptor activity; IEA:InterPro.
DR   GO; GO:0006606; P:protein import into nucleus; IEA:InterPro.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR000225; Armadillo.
DR   InterPro; IPR002652; Importin-a_IBB.
DR   PANTHER; PTHR23316; IMPORTIN ALPHA; 1.
DR   PANTHER; PTHR23316:SF6; IMPORTIN SUBUNIT ALPHA-4; 1.
DR   Pfam; PF00514; Arm; 5.
DR   Pfam; PF01749; IBB; 1.
DR   SMART; SM00185; ARM; 5.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   PROSITE; PS50176; ARM_REPEAT; 3.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233220};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        330..352
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          4..69
FT                   /note="IBB"
FT                   /evidence="ECO:0000259|Pfam:PF01749"
FT   REPEAT          90..134
FT                   /note="ARM"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT   REPEAT          133..160
FT                   /note="ARM"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT   REPEAT          260..298
FT                   /note="ARM"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
SQ   SEQUENCE   353 AA;  39109 MW;  7D603886F6A79B23 CRC64;
     LEIRRHTNVV KTVGNKRDEH LLKKRNVPQE ESLEDSDVDA DFKAQNVTLE AILQNATSDN
     PVVQLSAVQA ARKLLSSDRN PPIDDLIKSG ILPILVKCLE RDDNPSLQFE AAWALTNIAS
     GTSAQTQAVV QSNAVPLFLR LLHSPHQNVC EQAVWALGNI IGDGPQCRDY VISLGVVKPL
     LSFINPSIPI TFLRNVTWVI VNLCRNKDPP PPMETVQEIL PALCVLIYHT DINILVDTVW
     ALSYLTDGGN EQIQMVIDSG VVPFLVPLLS HQEVKVQTAA LRAVGNIVTG TDEQTQVVLN
     CDVLSHFPNL LSHPKEKINK VRHIMPSSCY FFLFLYLIFN CLLVSIATCL CFS
//