ID   A0A2K6UF49_SAIBB        Unreviewed;      1150 AA.
AC   A0A2K6UF49;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=Potassium sodium-activated channel subfamily T member 1 {ECO:0000313|Ensembl:ENSSBOP00000030548.1};
GN   Name=KCNT1 {ECO:0000313|Ensembl:ENSSBOP00000030548.1};
OS   Saimiri boliviensis boliviensis (Bolivian squirrel monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC   Saimiriinae; Saimiri.
OX   NCBI_TaxID=39432 {ECO:0000313|Ensembl:ENSSBOP00000030548.1, ECO:0000313|Proteomes:UP000233220};
RN   [1] {ECO:0000313|Ensembl:ENSSBOP00000030548.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; A0A2K6UF49; -.
DR   Ensembl; ENSSBOT00000047433.1; ENSSBOP00000030548.1; ENSSBOG00000031235.1.
DR   GeneTree; ENSGT00940000156880; -.
DR   Proteomes; UP000233220; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005216; F:monoatomic ion channel activity; IEA:UniProt.
DR   GO; GO:0071805; P:potassium ion transmembrane transport; IEA:UniProt.
DR   Gene3D; 1.10.287.70; -; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR   InterPro; IPR003929; K_chnl_BK_asu.
DR   InterPro; IPR013099; K_chnl_dom.
DR   InterPro; IPR047871; K_chnl_Slo-like.
DR   PANTHER; PTHR10027; CALCIUM-ACTIVATED POTASSIUM CHANNEL ALPHA CHAIN; 1.
DR   PANTHER; PTHR10027:SF14; POTASSIUM CHANNEL SUBFAMILY T MEMBER 1; 1.
DR   Pfam; PF03493; BK_channel_a; 1.
DR   Pfam; PF07885; Ion_trans_2; 1.
DR   SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
PE   4: Predicted;
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW   Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Potassium {ECO:0000256|ARBA:ARBA00022958};
KW   Potassium channel {ECO:0000256|ARBA:ARBA00022826};
KW   Potassium transport {ECO:0000256|ARBA:ARBA00022538};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233220};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        95..114
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        226..247
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        253..272
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        284..309
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          234..301
FT                   /note="Potassium channel"
FT                   /evidence="ECO:0000259|Pfam:PF07885"
FT   DOMAIN          459..531
FT                   /note="Calcium-activated potassium channel BK alpha
FT                   subunit"
FT                   /evidence="ECO:0000259|Pfam:PF03493"
FT   REGION          26..55
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          595..622
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          989..1020
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1124..1150
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        38..55
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1150 AA;  129770 MW;  5A39F4B0BD0DD437 CRC64;
     NGAQSPEGVY RETRCGVCTK RTFEFDGGGC APRHRPLRPP YTEAPVSPAP SGPEPPRPSL
     LLRVQVEFYV NENTFKERLK LFFIKNQRSS LRIRLFNFSL KLLTCLLYIV RVLLEDPALG
     IGCWGCPKQN YTFNDSTSEI NCFLETMLLI YLSYKGNIWE QIFRVSFVLE MINTLPFIIT
     IFWPPLRNLF IPVFLNCWLA KHALENMIND FHRAILRTQS AMFNQVLILF CTLLCLVFTG
     TCGIQHLERA GENLSLLTSF YFCIVTFSTV GYGDVTPKIW PSQLLVVIMI CVALVVLPLQ
     FEELVYLWME RQKSGGNYSR HRAQTEKHVV LCVSSLKIDL LMDFLNEFYA HPRLQDYYVV
     ILCPTEMDVQ VRRVLQIPLW SQRVIYLQGS ALKDQDLMRA KMDNGEACFI LSSRNEVDRT
     AADHQTILRA WAVKDFAPNC PLYVQILKPE NKFHVKFADH VVCEEECKYA MLALNCICPA
     TSTLITLLVH TSRGQEGQES PEQWQRMYGR CSGNEVYHIR MGDSKFFREY EGKSRLRPHA
     PSGRGGPGAG QLVILPEMTV CLFLELTGPG GWESGFGQAR SSFPGTVAMD LQGTEHRPTQ
     SVGGGGGSKL ALPTENGSGS RRPSIAPVLE LADSSALLPC DLLSDQSEDE VTPSDDEGLS
     VVEYVKGYPP NSPYIGSSPT LCHLLPVKAP FCCLRLDKGC KHNSYEDAKA YGFKNKLIIV
     SAETAGNGLY NFIVPLRAYY RSRKELNPIV LLLDNKPDHH FLEAICCFPM VYYMEGSVDN
     LDSLLQCGII YADNLVVVDK ESTMSAEEDY MADAKTIVNV QTMFRLFPSL SITTELTHPS
     NMRFMQFRAK DSYSLALSKL EKRERENGSN LAFMFRLPFA AGRVFSISML DTLLYQSFVK
     DYMITITRLL LGLDTTPGSG YLCAMKITEG DLWIRTYGRL FQKLCSSSAE IPIGIYRTES
     HVFSTSEPHD LRAQSQISVN MEDCEDTREV KGPWGARTGT GGSSHGRHTG GGDPTEHPLL
     RRKSLQWARR LSRRAPRQAG RAAAAEWISQ QRLSLYQRSE RQELSELVKN RMKHLGLPTT
     GYDEMNDHQN TLSYVLINPP PDTRLEPNDI VYLIRSDPLA HVASSSQSRK SSCSHKLSSC
     NPETRDETQL
//