ID A0A2K6UHP4_SAIBB Unreviewed; 1522 AA.
AC A0A2K6UHP4;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Dispatched RND transporter family member 1 {ECO:0000313|Ensembl:ENSSBOP00000031391.1};
GN Name=DISP1 {ECO:0000313|Ensembl:ENSSBOP00000031391.1};
OS Saimiri boliviensis boliviensis (Bolivian squirrel monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Saimiriinae; Saimiri.
OX NCBI_TaxID=39432 {ECO:0000313|Ensembl:ENSSBOP00000031391.1, ECO:0000313|Proteomes:UP000233220};
RN [1] {ECO:0000313|Ensembl:ENSSBOP00000031391.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the dispatched family.
CC {ECO:0000256|ARBA:ARBA00038046}.
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DR RefSeq; XP_010339220.1; XM_010340918.1.
DR RefSeq; XP_010339221.1; XM_010340919.1.
DR STRING; 39432.ENSSBOP00000031387; -.
DR Ensembl; ENSSBOT00000048275.1; ENSSBOP00000031387.1; ENSSBOG00000031918.1.
DR Ensembl; ENSSBOT00000048279.1; ENSSBOP00000031391.1; ENSSBOG00000031918.1.
DR GeneID; 101037815; -.
DR KEGG; sbq:101037815; -.
DR CTD; 84976; -.
DR GeneTree; ENSGT00940000157407; -.
DR OrthoDB; 2875706at2759; -.
DR Proteomes; UP000233220; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:1904680; F:peptide transmembrane transporter activity; IEA:Ensembl.
DR GO; GO:0007368; P:determination of left/right symmetry; IEA:Ensembl.
DR GO; GO:0060539; P:diaphragm development; IEA:Ensembl.
DR GO; GO:0009953; P:dorsal/ventral pattern formation; IEA:Ensembl.
DR GO; GO:0009880; P:embryonic pattern specification; IEA:Ensembl.
DR GO; GO:0007225; P:patched ligand maturation; IEA:Ensembl.
DR GO; GO:0015833; P:peptide transport; IEA:Ensembl.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR003392; Ptc/Disp.
DR InterPro; IPR000731; SSD.
DR PANTHER; PTHR45951:SF4; PROTEIN DISPATCHED HOMOLOG 1; 1.
DR PANTHER; PTHR45951; PROTEIN DISPATCHED-RELATED; 1.
DR Pfam; PF02460; Patched; 2.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR PROSITE; PS50156; SSD; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000233220};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 188..210
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 499..518
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 524..545
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 597..621
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 633..654
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 719..737
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 985..1004
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1010..1032
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1039..1059
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1079..1096
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1108..1127
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 524..658
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
FT REGION 1159..1181
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1417..1436
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1159..1175
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1417..1431
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1522 AA; 170648 MW; E8B00B4045C09A52 CRC64;
MAMSNGNNDF VVLSNSSITT SAANPNPLTL CDGDHAAQQL TPKEATRTKV SPNGCLQLNG
TVKSSLLPLD NQRTPQMLSQ CCHPCPYHHP LTSHSSHQEC HPEAGPAAPS ALASCCMQPH
SEYSASLCPN HSPVYQTTCC LQPSPSFCLH HPWPDHFQHQ PVQQHIANIR PSRPFKLPKS
YAALIADWPV GVLGMCTMFI VVCALVGILV PELPDFSDPL LGFEPRGTAI GQRLVTWNNM
VNNTGYKATL ANYPFKYADE QAKSHRDDRW SDDHYEREKR EVDWNFHKDS FFCDVPSDRY
SRMVFTSSGG ETLWNLPAIK SMCNVDNSRI RSHPQFGDLC QRTTAASCCP SWTLGNYIAI
LNNRSSCQKI VERDVSHTLK LLRTCAKHYQ NGTLGPDCWD MAARRKDQLK CTNVPRKCTK
YNAVYQILHY LVDKDFITPK TADYATPALK YSMLFSPTEK GESMMNIYLD NFENWNSSDG
VTTITGIEFG IKHSLFQDYL LMDTVYPAIA IVIVLLVMCV YTKSMFITLM TMFAIISSLI
VSYFLYRVVF HFEFFPFMNL TALIILVGIG ADDAFVLCDV WNYTKFDKPH AETSETVSIT
LQHAALSMFV TSFTTAAAFY ANYVSNITAI RCFGVYAGTA ILVNYVLMVT WLPAVVVLHE
RYLLNIFTCF KKPQQQICDN KSCWTVACRK CHKVLFAVSE ASRIFFEKVL PCIVIKFRYL
WLFWFLALTV GGAYIVCINP KMKLPSLELS EFQVFRSSHP FERYDAEYKK LFMFERVHHG
EELHMPITVI WGVSPEDNGN PLNPKNKGKL TLDSSFNIAS PASQAWILHF CQKLRNQTFF
YQTDEQDFTS CFIETFKQWM ENQDCDEPAL YPCCSHWSFP YKQEIFELCI KRAIMELERS
TGYHLYKKTP GPRFDINDTI RAVVLEFQST YLFTLAYEKM HQFYKEVDSW ISNELSSAPE
GLSNGWFVSN LEFYDLQDSL SDGTLIAMGL SVAVAFSVML LTTWNIVISL YAIISIAGTI
FVTVGSLVLL GWELNVLESV TISVAVGLSV DFAVHYGVAY RLAPDPDREG KVIFSLSRMG
SAIAMAALTT FVAGAMMMPS TVLAYTQLGT FMMLIMCISW AFATFFFQCM CRCLGPQGTC
GQIPLPRKLQ RSAFSQALSA SPSDKGQSKT HTINAYHLDP RSPKSELEHE FYELEPLASH
SSTASEKTTY EETHICSEFF NSQAKNLGMP VHAAYNSELS QSTKNDPGSA LLQPSLEQHT
MCHFFSLNQR CSCPNAYKCL KYGPHSCQQM GECLCHQCAP TASSFVQLQN GVASLKVTPQ
AAEGFVHPLT HIHPCPCLQG RVKPAGMQNS LSTNIFLHPA QQIQAQERIG KTNVHSLQST
EEHLPKMAAP SSFVCRSTGS LLKTCCDPEN KQREHCKNRD VGKESGGETE NKPGGKVELS
LSQMDASVNS EHLNQNEPKV IFNHLMGEAG CRSCPNNSQS CDRIVRMKCN SADCQMPNIE
ANVPAVLTHS ELSGESLLIK TL
//
