ID A0A2K6UKQ7_SAIBB Unreviewed; 2734 AA.
AC A0A2K6UKQ7;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Neurobeachin like 2 {ECO:0000313|Ensembl:ENSSBOP00000032500.1};
GN Name=NBEAL2 {ECO:0000313|Ensembl:ENSSBOP00000032500.1};
OS Saimiri boliviensis boliviensis (Bolivian squirrel monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Saimiriinae; Saimiri.
OX NCBI_TaxID=39432 {ECO:0000313|Ensembl:ENSSBOP00000032500.1, ECO:0000313|Proteomes:UP000233220};
RN [1] {ECO:0000313|Ensembl:ENSSBOP00000032500.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR Ensembl; ENSSBOT00000049401.1; ENSSBOP00000032500.1; ENSSBOG00000032401.1.
DR GeneTree; ENSGT00940000158454; -.
DR Proteomes; UP000233220; Unplaced.
DR CDD; cd06071; Beach; 1.
DR CDD; cd01201; PH_BEACH; 1.
DR Gene3D; 1.10.1540.10; BEACH domain; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000409; BEACH_dom.
DR InterPro; IPR036372; BEACH_dom_sf.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR046851; NBCH_WD40.
DR InterPro; IPR031570; NBEA/BDCP_DUF4704.
DR InterPro; IPR046852; Neurobeachin_a-sol.
DR InterPro; IPR023362; PH-BEACH_dom.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR13743; BEIGE/BEACH-RELATED; 1.
DR PANTHER; PTHR13743:SF111; NEUROBEACHIN-LIKE PROTEIN 2; 1.
DR Pfam; PF02138; Beach; 1.
DR Pfam; PF15787; DUF4704; 1.
DR Pfam; PF16057; DUF4800; 1.
DR Pfam; PF20426; NBCH_WD40; 1.
DR Pfam; PF20425; Neurobeachin; 1.
DR Pfam; PF14844; PH_BEACH; 1.
DR SMART; SM01026; Beach; 1.
DR SMART; SM00320; WD40; 3.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF81837; BEACH domain; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50197; BEACH; 1.
DR PROSITE; PS51783; PH_BEACH; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 2.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000233220};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT DOMAIN 1895..2020
FT /note="BEACH-type PH"
FT /evidence="ECO:0000259|PROSITE:PS51783"
FT DOMAIN 2033..2325
FT /note="BEACH"
FT /evidence="ECO:0000259|PROSITE:PS50197"
FT REPEAT 2478..2511
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 2529..2570
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 1282..1322
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1347..1421
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1990..2009
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1286..1310
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1347..1370
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1406..1421
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2734 AA; 299927 MW; 8E9C113961750942 CRC64;
KDLGYLQQWL KAFVGTFKKS ISLSSLEPRR PEEAGAEVPL LPLDALHVLA EQLHQEDLEQ
ALLLLKLFII LCRNLENIEA DRGQVLAPRV LALLTKLVAE LKGCPPPQGR GAQLENVALH
ALLLCEGLFD PYQTWRRQRS GEVISSKEKS KYKFPPAALP REFRAFFQES LQNADRLPPV
LLLRLIHLFC AVLAGGKENG QMAVSDGSVQ GLLSVVRGWG RGPAQDPHLV LLALEALVGA
VHVLHASRAP PRGPELRTLL ESYFHVLNAD WPAGVSSGPE EALVTLRVSM LDAIPMMLAC
EDRPVLQATF LSNNCFEHLT RLIQNSKLYL QARAPLEGDS DLATRLLTEP DVQKVLDQDT
DAIAVHVVRV LTCIMSGSPS AKEVFKERIG YPHLQEVLQS HGPPTHRLLQ ELLNMAVEGD
HSMCPPPPIC NEQPVLVLVQ WLPSLPTAEL RLFLAQRLRW LCDSCPASRA TCVQAGLVAC
LLETLSTGLA LGARCQEQLL ALLQALGRVS LRPMELRHLL RPPPGLDSEP GGAEAGKARH
AGAVIRALSG MARHQGPARA LRYFDLKPSM AGIMVPPVQR WPGPGFTFHA WLCLHPMDTA
PTPAPTQPLQ RKQLYSFFTS SGSGFEAFFT AAGTLVVAVC TRKEYLTMSL PEVSFADSAW
HCVAIIHVPG RRPFSQNLVH VYKDGLLVKT APLRCPSLSE PFSSCCIGSA GHRTTTTTTG
LPTPPVPATL ACSHPTLARS QSVPASTGLG WGSGLVAPLQ EGSINSTLAG TQDTRWGSPT
SLEGELGAVA IFHEALQAAA VRTLCILGPN ETAPFKPEGE LHELSTKLLL HYSPQACKNN
ICLDLSPSHG LDGRLTGHRV ETWDVKDVVN CVGGMGALLP LLERVAAQPQ EAEAGPAETH
DLVGPELTSG HNTQGLLLPL GKSSEERMER NAVAAFLLML RNFLQGHVVN QESLVQCQGA
AIIGALLRKV PSWAMDMNVL MSAQLLMEQL AAEGSRPLLY LLYQHLLFNF HLWTLSNFAV
RLGHIQYMSS IVREHRQKLR KKYGVQFILD ALRTHYSLQR ERPLAADDLR TVQTSLLGLV
REFLVRSLSA DDVQVMQILM GFLVATGDDG QVVGALDLLL ALLQGSLAQE SLAIFLLDPG
NLEVLLALLV RPGSLPLLPD RVCKILHRLQ QNERLPERSR QRLRLRECGL QGLVACLPEG
TVSPQLCQGL YKLFLGADCL NLSDLLAVVQ LSLQADLGVR LEICRQLFHL IYRQPDAVRL
LARQAGWQDV LTRLYVLEAA TAGSPAPASP EPPTSPEPAP PKPPTELPAE PSDVFLPSEA
PCPDPDGIYH ALSPFCTPFD LGLERASVGS GNTTGGGGSS GTLTPASQPG TPSPLDGPRP
FPAAPGRHSS SLSNVLEDGS LPEPIISGDD TSNTSNPQQT SEEELCNLLT NVLFSVTWRG
VEGSDEAAWR ERGQVFSVLT QLGASATLVR PPDCIKRSLL EMMLESVLTD IKEAPVGVLA
SLTQQALWLL RLLQDFLCAE GHGNQELWSE KLFEGVCSLL DRLEAWPHLA NGTADLREMA
QVGLRLVLGY ILLEDPQLHA QAYVKLHMLL QTVVPARREE ACYVLSKLEA ALGRALNTSS
SESAADEAGP PPAAAAATER CSWLVPLVRT LLDRAYEPLG LQWGLPSLPP TNGSPTFFED
FQAFCATPEW RHFIDKQVQP TMSQFEMDTY AKSHDLMSGF WNACYDMLMS SGQRRQRERA
QSRRAFQELV LEPAQRRARL EGLRYSAALK QRAAQHSTAL LHWGALWRQL SSPCGAWALR
DPPTPRWKLS SAETYSRMRL KLVPNHHFDP HLEASALRDN LGEVPLTPTE EASLPLAVTK
EAKVSTPPEE LQEDQLGEEE LAALETPMEA AELDEQREKL VLSAECQLVT VVAVVPGLLE
ITTQNVYFYD GSTERVETEE GIGYDFRRPL AQLREVHLRR FNLRRSALEL FFIDQANYFL
NFPCKVGTTP ASSPSQASRP QPSPSPPHTQ VRNQVYSWLL RLRPPSQGYL SSRSPQEMLR
ASGLTQKWVQ REISNFEYLM QLNTIAGRTY NDLSQYPVFP WVLQDYVSPT LDLSNPAVFR
DLSKPIGVVN PKHAQLVREK YESFEDPAGT IDKFHYGTHY SNAAGVMHYL IRVEPFTSLH
VQLQSGRFDC SDRQFHSVAA AWQARLESPA DVKELIPEFF YFPDFLENQN GFDLGCLQLT
NEKVGDVVLP PWASSPEDFI QQHRQALESE YVSAHLHEWI DLIFGYKQRG PAAEEALNVF
YYCTYEGAVD LDHVTDERER KALEGIISNF GQTPCQLLKE PHPTRLSAEE AALRLARLDT
NSPSIFQHLD QLKAFFAEVI SDGVPLVLAL VPHRQPHSFI TQGSPDLLVT VSANGLLGTH
SWLPYDRNIS NYFSFSKDPT MGSHKTQRLL SGPWAPGSGV SGQALAVAPD GKLLFSGGHW
DGSLRVTALS RGKLLSQLSR HLDVVTCLAL DTCGIYLISG SRDTTCMVWR LLHQGGLSVG
LAPKPVQVLY GHGAAVSCVA ISTELDMAVS GSEDGTVIIH TVRRGQFVAA LQPPGATFSG
PVSYLALGSE GQIVVQSSAW ERPGAQATYS LHLYSVNGKL RASLPLAERP TALTVTEDFV
LLGTAQCALH ILQLNTLLPA APPLTMKVAI RSVAVTKERS HVLVGLEDGK LIVVGAGQPS
EVRSSQFARR LWRSSRRISQ VSSGETEYNP TEAR
//
