ID   A0A2K6UM67_SAIBB        Unreviewed;       349 AA.
AC   A0A2K6UM67;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   24-JAN-2024, entry version 23.
DE   SubName: Full=SH3 domain containing GRB2 like 2, endophilin A1 {ECO:0000313|Ensembl:ENSSBOP00000032996.1};
GN   Name=SH3GL2 {ECO:0000313|Ensembl:ENSSBOP00000032996.1};
OS   Saimiri boliviensis boliviensis (Bolivian squirrel monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC   Saimiriinae; Saimiri.
OX   NCBI_TaxID=39432 {ECO:0000313|Ensembl:ENSSBOP00000032996.1, ECO:0000313|Proteomes:UP000233220};
RN   [1] {ECO:0000313|Ensembl:ENSSBOP00000032996.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the endophilin family.
CC       {ECO:0000256|ARBA:ARBA00006697}.
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DR   AlphaFoldDB; A0A2K6UM67; -.
DR   STRING; 39432.ENSSBOP00000032996; -.
DR   Ensembl; ENSSBOT00000049904.1; ENSSBOP00000032996.1; ENSSBOG00000032645.1.
DR   GeneTree; ENSGT00940000160529; -.
DR   Proteomes; UP000233220; Unplaced.
DR   GO; GO:0048471; C:perinuclear region of cytoplasm; IEA:Ensembl.
DR   GO; GO:0042802; F:identical protein binding; IEA:Ensembl.
DR   GO; GO:1905604; P:negative regulation of blood-brain barrier permeability; IEA:Ensembl.
DR   GO; GO:0010629; P:negative regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0001933; P:negative regulation of protein phosphorylation; IEA:Ensembl.
DR   CDD; cd07613; BAR_Endophilin_A1; 1.
DR   Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR   InterPro; IPR027267; AH/BAR_dom_sf.
DR   InterPro; IPR004148; BAR_dom.
DR   PANTHER; PTHR14167:SF50; ENDOPHILIN-A1; 1.
DR   PANTHER; PTHR14167; SH3 DOMAIN-CONTAINING; 1.
DR   Pfam; PF03114; BAR; 1.
DR   SMART; SM00721; BAR; 1.
DR   SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR   PROSITE; PS51021; BAR; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000233220}.
FT   DOMAIN          9..240
FT                   /note="BAR"
FT                   /evidence="ECO:0000259|PROSITE:PS51021"
FT   REGION          1..21
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          238..278
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        256..272
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   349 AA;  40293 MW;  CE3F61693FBD8189 CRC64;
     RKGRKNKVSE KVGGAEGTKL DDDFKEMERK VDVTSRAVME IMTKTIEYLQ PNPASRAKLS
     MINTMSKIRG QEKGPGYPQA EALLAEAMLK FGRELGDDCN FGPALGEVGE AMRELSEVKD
     SLDIEVKQNF IDPLQNLHDK DLREIQHHLK KLEGRRLDFD YKKKRQGKIP DEELRQALEK
     FDESKEIAES SMFNLLEMDI EQVSQLSALV QAQLEYHKQA VQILQQVTVR LEERIRQASS
     QPRREYQPKP RMSLEFPTGD STQPNGGLSH TGTPKPSGKE LRLQIVLHRP WHIHWHFSRN
     CRNNPIWLHR KYAVIYFLWG GLSGRNSVKE FLLSFFIDRF LSFLFSSSL
//