ID A0A2K6URF1_SAIBB Unreviewed; 837 AA.
AC A0A2K6URF1;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE SubName: Full=L3MBTL histone methyl-lysine binding protein 1 {ECO:0000313|Ensembl:ENSSBOP00000034501.1};
GN Name=L3MBTL1 {ECO:0000313|Ensembl:ENSSBOP00000034501.1};
OS Saimiri boliviensis boliviensis (Bolivian squirrel monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Saimiriinae; Saimiri.
OX NCBI_TaxID=39432 {ECO:0000313|Ensembl:ENSSBOP00000034501.1, ECO:0000313|Proteomes:UP000233220};
RN [1] {ECO:0000313|Ensembl:ENSSBOP00000034501.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR AlphaFoldDB; A0A2K6URF1; -.
DR STRING; 39432.ENSSBOP00000034501; -.
DR Ensembl; ENSSBOT00000051424.1; ENSSBOP00000034501.1; ENSSBOG00000033395.1.
DR GeneTree; ENSGT00940000159708; -.
DR Proteomes; UP000233220; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd20131; MBT_L3MBTL1_rpt1; 1.
DR CDD; cd20134; MBT_L3MBTL1_rpt2; 1.
DR CDD; cd20137; MBT_L3MBTL1_rpt3; 1.
DR Gene3D; 2.30.30.140; -; 3.
DR Gene3D; 4.10.320.30; -; 1.
DR InterPro; IPR004092; Mbt.
DR InterPro; IPR047361; MBT_L3MBTL1_rpt1.
DR InterPro; IPR047362; MBT_L3MBTL1_rpt3.
DR InterPro; IPR002515; Znf_C2H2C.
DR InterPro; IPR036060; Znf_C2H2C_sf.
DR PANTHER; PTHR12247:SF69; LETHAL(3)MALIGNANT BRAIN TUMOR-LIKE PROTEIN 1; 1.
DR PANTHER; PTHR12247; POLYCOMB GROUP PROTEIN; 1.
DR Pfam; PF02820; MBT; 3.
DR Pfam; PF01530; zf-C2HC; 1.
DR SMART; SM00561; MBT; 3.
DR SUPFAM; SSF103637; CCHHC domain; 1.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 3.
DR PROSITE; PS51079; MBT; 3.
DR PROSITE; PS51802; ZF_CCHHC; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000233220};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU01143}.
FT REPEAT 274..374
FT /note="MBT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00459"
FT REPEAT 382..481
FT /note="MBT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00459"
FT REPEAT 490..585
FT /note="MBT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00459"
FT REGION 127..275
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 657..694
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 143..157
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 162..211
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 222..246
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 254..269
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 673..691
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 837 AA; 92253 MW; 644ACDA3F5D503ED CRC64;
VHLVARDSPG SGPHLPATAF IIPASSATLS LPSSALDVSC FPREPIHVGV PEQVAGSEPV
PAAVLPQLSA GPASSSASTV RLLEWTEAVA PPPGSGLRFR ISEYKPLNMA AVEQPPTPEL
RREGVTEYKD GGAPAGNGEA HLAPAEDHPH NPPEEPSQEP PEDDSTCQCQ ACGPQQAAGP
DLGSSNDGCP QLFQERSVIV ENSSGSTSTS EHLKPMKKRK RREYQSPSEE ESEPEAMEKQ
EEGKDPEGQP TAGTPESEEW SSNQPATGEK KEGWSWESYL EEQKAITAPV SLFQDSQAVT
HNKNGFKLGM KLEGIDPQHP SMYFILTVAE VCGYRLRLHF DGYSECHDFW VNANSPDIHP
AGWFEKTGHK LQPPKGYKEE EFSWSQYLRS TRAQAAPKHL FVSQSHSPPP LGFQVGMKLE
AVDRMNPSLV CVASVTDVVD SRFLVHFDNW DDTYDYWCDS SSPYIHPVGW CQKQGKPLTP
PQDYPDPDNF CWEKYLEETG ASAVPAWAFK VRPPHSFLVN MKLEAVDRRN PALIRVASVE
DVEDHRIKIH FDGWSHGYDF WIDADHPDIH PAGWCSKTGH PLQPPLRLRE PSSASPGGCP
PLSCRSLPHT RTSKYSFHHR KCPTPGCDGS GHVTGKFTAH HCLSGCPLAE RNQSRLKAEL
SDSEASARKK NLSGFSPRKK PRHHGRIGRP PKYRKIPQED FQTLTPDAVH QSLFMSALSA
HPDRSLSVCW EQHCKLLPGV AGISASTVAK WTIDEVFGFV QTLTGCEDQA RLFKDEVRCK
VTHVSEMNVV WTVAQLRDLV CSNLQEGNGI LETGVRSLLC SLPTHVLAKL SFTSDSK
//
