ID   A0A2K6V7S3_SAIBB        Unreviewed;       921 AA.
AC   A0A2K6V7S3;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   24-JAN-2024, entry version 21.
DE   RecName: Full=RBR-type E3 ubiquitin transferase {ECO:0000256|ARBA:ARBA00012251};
DE            EC=2.3.2.31 {ECO:0000256|ARBA:ARBA00012251};
GN   Name=RNF31 {ECO:0000313|Ensembl:ENSSBOP00000040208.1};
OS   Saimiri boliviensis boliviensis (Bolivian squirrel monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC   Saimiriinae; Saimiri.
OX   NCBI_TaxID=39432 {ECO:0000313|Ensembl:ENSSBOP00000040208.1, ECO:0000313|Proteomes:UP000233220};
RN   [1] {ECO:0000313|Ensembl:ENSSBOP00000040208.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine +
CC         [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC         cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.;
CC         EC=2.3.2.31; Evidence={ECO:0000256|ARBA:ARBA00001798};
CC   -!- SIMILARITY: Belongs to the RBR family. {ECO:0000256|ARBA:ARBA00008278}.
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DR   AlphaFoldDB; A0A2K6V7S3; -.
DR   Ensembl; ENSSBOT00000057174.1; ENSSBOP00000040208.1; ENSSBOG00000036097.1.
DR   GeneTree; ENSGT00530000064112; -.
DR   Proteomes; UP000233220; Unplaced.
DR   GO; GO:0071797; C:LUBAC complex; IEA:InterPro.
DR   GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0019538; P:protein metabolic process; IEA:UniProt.
DR   CDD; cd19815; Bbox1_HOIP; 1.
DR   CDD; cd20337; BRcat_RBR_HOIP; 1.
DR   CDD; cd16631; mRING-HC-C4C4_RBR_HOIP; 1.
DR   CDD; cd20351; Rcat_RBR_HOIP; 1.
DR   CDD; cd14325; UBA_RNF31; 1.
DR   Gene3D; 1.20.120.1750; -; 1.
DR   Gene3D; 6.10.140.1100; -; 1.
DR   Gene3D; 1.10.8.10; DNA helicase RuvA subunit, C-terminal domain; 1.
DR   Gene3D; 4.10.1060.10; Zinc finger, RanBP2-type; 1.
DR   Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR   InterPro; IPR047543; Bbox1_RNF31-like.
DR   InterPro; IPR047540; BRcat_RBR_RNF31-like.
DR   InterPro; IPR002867; IBR_dom.
DR   InterPro; IPR047542; Rcat_RBR_RNF31-like.
DR   InterPro; IPR026254; RNF31-like.
DR   InterPro; IPR032065; RNF31-UBA.
DR   InterPro; IPR041031; RNF31_C.
DR   InterPro; IPR047541; RNF31_RBR_mRING-HC-like.
DR   InterPro; IPR044066; TRIAD_supradom.
DR   InterPro; IPR015940; UBA.
DR   InterPro; IPR047539; UBA_RNF31.
DR   InterPro; IPR001876; Znf_RanBP2.
DR   InterPro; IPR036443; Znf_RanBP2_sf.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   InterPro; IPR017907; Znf_RING_CS.
DR   PANTHER; PTHR16004:SF2; E3 UBIQUITIN-PROTEIN LIGASE RNF31; 1.
DR   PANTHER; PTHR16004; RING FINGER PROTEIN 31-RELATED; 1.
DR   Pfam; PF18091; E3_UbLigase_RBR; 1.
DR   Pfam; PF16678; HOIP-UBA; 1.
DR   Pfam; PF01485; IBR; 1.
DR   SMART; SM00647; IBR; 2.
DR   SMART; SM00547; ZnF_RBZ; 3.
DR   SUPFAM; SSF90209; Ran binding protein zinc finger-like; 1.
DR   SUPFAM; SSF57850; RING/U-box; 3.
DR   PROSITE; PS51873; TRIAD; 1.
DR   PROSITE; PS50030; UBA; 1.
DR   PROSITE; PS01358; ZF_RANBP2_1; 3.
DR   PROSITE; PS50199; ZF_RANBP2_2; 2.
DR   PROSITE; PS00518; ZF_RING_1; 1.
PE   3: Inferred from homology;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233220};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00322}.
FT   DOMAIN          148..178
FT                   /note="RanBP2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50199"
FT   DOMAIN          199..228
FT                   /note="RanBP2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50199"
FT   DOMAIN          413..464
FT                   /note="UBA"
FT                   /evidence="ECO:0000259|PROSITE:PS50030"
FT   DOMAIN          544..778
FT                   /note="RING-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51873"
FT   REGION          112..139
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          292..333
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   921 AA;  102618 MW;  A91C5ECD52662E6E CRC64;
     MDLCTRAGEL SLTQNTHPRQ QALEQLLEDK VEDDMLQLSE LDPLLREIAS GPLTTPSAPG
     STPGPCFLCG SAPGTLHCPS CKHALCPACD HLFHGHPSRA HHLRQTLPGV LQGTHLSPSL
     PASAQPRPQS TSLLALGDSS LSSPNPASAR LPWHCAACAM LNEPWAVLCV ACDRPRGCKG
     LGLGTDGPHG TGGLEPELAR GRWACQSCTF ENEAVAVLCS ICERPRLAQP PSLVVDSRDA
     GICLQPLQQG DTLLASAQTQ VWYCIHCTFC NSSPGWVCVM CNRTSNPIPV QHAPRPHASS
     LEKGLPKPGP PQRLSAPLPS SCGDPEKQRQ DKMREEGLQL VSMIQEGEAA GACPEEIFSA
     LQYSGTEVPL QWLRSELPYV LEMVAELAGQ QDPGLGAFSC QEARKAWLDR HGNLDEAVEE
     CVRTRRRKVQ ELQSLGFGPE EGSLQALFQH GGDVSRALTE LQRQRLEPFR QRLWDSGPEP
     TPSWDGPDKQ SLVRRLLAVY TLPSWGRAEL ALSLLQETPR NYELGDVVEA VRHSQDRAFL
     RRLLAQECAV CGWALPHNRM QALTSCECTI CPECFRQHFT IALKEKHITD MVCPACGRPD
     LTDDTQLLSY FSTLDIQLRE SLEPDAYALF HKKLTEGVLM RDPKFLWCAQ CSFGFIYERE
     QLEATCPQCH QTFCVRCKRQ WEEQHRGRSC EDFQNWKRMN DPEYQAQGLA MYLQENGIDC
     PKCKFSYALA RGGCMHFHCT QCRHQFCSGC YNAFYAKNKC PEPNCRVKKS LHGHHPRDCL
     FYLRDWTALR LQKLLQDNNI MFNTEPPAGA RAVPGGGCRV MEQKEVPNGL RDEACGKETP
     AGYAGLCQAH YKEYLVSLIN AHSLDPATLY EMEELETATE RYLHVRPQPL AGEDPPAYQA
     RLLQKLTEEV PLGQSIPRRR K
//