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Database: UniProt
Entry: A0A2K6VSF6_ONCVO
LinkDB: A0A2K6VSF6_ONCVO
Original site: A0A2K6VSF6_ONCVO 
ID   A0A2K6VSF6_ONCVO        Unreviewed;       362 AA.
AC   A0A2K6VSF6;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   08-MAY-2019, entry version 9.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblMetazoa:OVOC1902.2};
OS   Onchocerca volvulus.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Onchocerca.
OX   NCBI_TaxID=6282 {ECO:0000313|EnsemblMetazoa:OVOC1902.2, ECO:0000313|Proteomes:UP000024404};
RN   [1] {ECO:0000313|EnsemblMetazoa:OVOC1902.2, ECO:0000313|Proteomes:UP000024404}
RP   NUCLEOTIDE SEQUENCE.
RA   Cotton J., Tsai J., Stanley E., Tracey A., Holroyd N., Lustigman S.,
RA   Berriman M.;
RT   "Genome sequencing of Onchocerca volvulus.";
RL   Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:OVOC1902.2}
RP   IDENTIFICATION.
RG   EnsemblMetazoa;
RL   Submitted (FEB-2018) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU003822};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU003822}.
CC   -!- SIMILARITY: Belongs to the inward rectifier-type potassium channel
CC       (TC 1.A.2.1) family. {ECO:0000256|RuleBase:RU003822,
CC       ECO:0000256|SAAS:SAAS00549381}.
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DR   EMBL; CMVM020000058; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EnsemblMetazoa; OVOC1902.1; OVOC1902.1; WBGene00238711.
DR   EnsemblMetazoa; OVOC1902.2; OVOC1902.2; WBGene00238711.
DR   OMA; KDMNVGY; -.
DR   Proteomes; UP000024404; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005242; F:inward rectifier potassium channel activity; IEA:InterPro.
DR   GO; GO:0034765; P:regulation of ion transmembrane transport; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.1400; -; 1.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR041647; IRK_C.
DR   InterPro; IPR016449; K_chnl_inward-rec_Kir.
DR   InterPro; IPR013518; K_chnl_inward-rec_Kir_cyto.
DR   InterPro; IPR040445; Kir_TM.
DR   PANTHER; PTHR11767; PTHR11767; 1.
DR   Pfam; PF01007; IRK; 1.
DR   Pfam; PF17655; IRK_C; 1.
DR   PRINTS; PR01320; KIRCHANNEL.
DR   SUPFAM; SSF81296; SSF81296; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000024404};
KW   Ion channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434609};
KW   Ion transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434639};
KW   Membrane {ECO:0000256|SAAS:SAAS00434581, ECO:0000256|SAM:Phobius};
KW   Potassium {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434575};
KW   Potassium transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434641};
KW   Reference proteome {ECO:0000313|Proteomes:UP000024404};
KW   Transmembrane {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434543, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00036756,
KW   ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00036755};
KW   Voltage-gated channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00048561}.
FT   TRANSMEM     61     84       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    134    161       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       26    163       IRK. {ECO:0000259|Pfam:PF01007}.
FT   DOMAIN      170    343       IRK_C. {ECO:0000259|Pfam:PF17655}.
SQ   SEQUENCE   362 AA;  41932 MW;  1D73DDB963546016 CRC64;
     MDDNDNHEAL LSLPLKENKI CRPRLVAKNG RCILRQIGMP NPCRSIYRNW FHLVIECSWR
     VILCVFASGF IITWITFALI YYIIVLPDQS LQKPENEQCI ANVYDLKTAF LFSLETQHTI
     GYGFRYVTDA CLSLVFFLSL QCIAGVFMQT MLSGIVVAKL LRPKKRKQEI RFSQVAVIGP
     MSDTDRRPAL MIRIADIQNN LYIAEPHVRL YIATSQINKK GERELAHFKD LNVGYDSGWD
     RVLLLWPITV KHLIDDQSPL FTMTPDEIHN AHFELIMIVE GIVEATGMTF QARTSFLPNE
     ILWGYRFRSM VILNEKIGRY EIQYKLFDEI ESIDGINFKV MEIDDDDDND NYDSSRNHSG
     FI
//
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