ID A0A2K8K5B9_9RHOB Unreviewed; 918 AA.
AC A0A2K8K5B9;
DT 25-APR-2018, integrated into UniProtKB/TrEMBL.
DT 25-APR-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=TIR domain-containing protein {ECO:0000259|PROSITE:PS50104};
GN ORFNames=BG454_01190 {ECO:0000313|EMBL:ATX64619.1};
OS Rhodobaca barguzinensis.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Paracoccaceae; Rhodobaca.
OX NCBI_TaxID=441209 {ECO:0000313|EMBL:ATX64619.1, ECO:0000313|Proteomes:UP000228948};
RN [1] {ECO:0000313|EMBL:ATX64619.1, ECO:0000313|Proteomes:UP000228948}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=alga05 {ECO:0000313|Proteomes:UP000228948};
RA Kopejtka K., Tomasch J.M., Bunk B., Koblizek M.;
RT "Revised Sequence and Annotation of the Rhodobaca barguzinensis strain
RT alga05 Genome.";
RL Submitted (NOV-2017) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP024899; ATX64619.1; -; Genomic_DNA.
DR RefSeq; WP_071480033.1; NZ_SODJ01000015.1.
DR AlphaFoldDB; A0A2K8K5B9; -.
DR STRING; 441209.GCA_001870665_00997; -.
DR KEGG; rbg:BG454_01190; -.
DR OrthoDB; 235631at2; -.
DR Proteomes; UP000228948; Chromosome.
DR GO; GO:0005829; C:cytosol; IEA:UniProt.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 1.25.40.370; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 3.
DR InterPro; IPR041452; APAF1_C.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000157; TIR_dom.
DR InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR19848:SF8; E3 UBIQUITIN-PROTEIN LIGASE TRAF7; 1.
DR PANTHER; PTHR19848; WD40 REPEAT PROTEIN; 1.
DR Pfam; PF17908; APAF1_C; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF13676; TIR_2; 1.
DR Pfam; PF00400; WD40; 6.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00320; WD40; 7.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50104; TIR; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 2.
DR PROSITE; PS50082; WD_REPEATS_2; 6.
DR PROSITE; PS50294; WD_REPEATS_REGION; 6.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000228948};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT DOMAIN 1..129
FT /note="TIR"
FT /evidence="ECO:0000259|PROSITE:PS50104"
FT REPEAT 627..668
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 670..711
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 713..754
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 756..787
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 799..840
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 842..883
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
SQ SEQUENCE 918 AA; 99678 MW; 185D72B1DE087FC2 CRC64;
MSARIFISYA RADGGDASER LIKLLASNGH SAWKDLRELG PEKTVWPQIE QALETAEFLI
VLITPAALKS EYIRKEWREA RRNGATMMPV MAMKQSRSTL PRWLRRGEVY DLTEPAHREK
FLARLNSTGG TFRADWDAGL EIETFIARPR LFAQIKAQLL SETSEPLSLT SALQGRGGYG
KSVLAGEIAR DPEIRDAYID GVFWVSLGQD NPDVLGQINH LIRRISGAGG APDVNTAAEE
LRRLLEKRDV LIILDDVWRR QDLYTFAKAT GQGNASLLAT TRKLDALPPS AQTIDISGME
PDEAVALLSY GLAPNATEQR ALSAFAADFW HWPQLLAIAK GLLRGRLRDG ETLLHALKTI
ADGARRGVVP GTDERERTIA NVMQMGIDDL DPADRERFKA LAVVPEDTAI PVAILAPLWR
LSQYEAEEFA RLLLDRRLIQ SRDLSDPSVG ARIRMHDDML WYLGAIADET SKRALHSALL
GLHRPASGNW AELGQDRSAL HYLWRYLLWH LEQAGEDETA NALRIDYAWI KAKLTLMGID
GLLTDYRLRP ADRSAALVGN ALQLSRHALD HDRGQLGFQL FGRLNDVCRN QFETLCTNAK
LDTSPLSPVL LRLALDGAEL DLRLMRLGGH EGSISSVACS PDNSCIVSGG IDGTLRLWDA
ETGAALGEPL HGHEGGFWSV AFSPDGSRII SGGDDGMLRL WDTATGAALG EPQRRQRGLV
RCFAFSPDGN RIAGCGRDGT LRLWDAATAA ALSKPLGGHE DMVSSAAFSP DGSRIVSGGA
DGTLCLWGGA TGAAMGEPLR GHEDWITSVA FSPCGRRFVS GCSDGMLCLW NTSTGAALSA
PLRGHEDMVL SVILTPDGSH IVSGAADGTL CLWSAVTGKV MGVMTFDAEI TSVAGSQTLL
AVGDALGNVH ILHWNVIT
//
